Patents Examined by Elli Peselev
  • Patent number: 9259389
    Abstract: The present invention concerns a pharmaceutical formulation intended for oral administration containing a synthetic oligosaccharides containing one to 18 monosaccharide units and having a therapeutical activity or a pharmaceutically acceptable additions salt or solvate thereof wherein the formulation contains: a) the synthetic oligosaccharide (A) in an amount of up to 5% by weight of the total weight of the formulation, advantageously up to 1% by weight of the total weight of the formulation, b), a lipophilic phase (B) consisting of triglyceride of fatty acids in an amount of 50 to 80% by weight of the total weight of the formulation, advantageously of 50 to 70% by weight of the total weight of the formulation, c) at least one lipophilic surfactant (C) with HLB below 7 consisting of partial esters of polyol and fatty acids in an amount of 10 to 30% by weight of the total weight of the formulation, advantageously of 15 to 30% by weight of the total weight of the formulation, d) at least one hydrophilic surfact
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: February 16, 2016
    Assignees: ENDOTIS PHARMA, CATALENT FRANCE BEINHEIM SA
    Inventors: Julien Meissonnier, Nathalie Sicre, Guillaume Sabate, Guy Dubreucq, Vanessa Nancy-Portebois, Maurice Petitou
  • Patent number: 9247742
    Abstract: A synergistic fungicidal mixture contains a fungicidally effective amount of a compound of Formula I and at least one fungicide selected from the group consisting of tricyclazole, azoxystrobin, carpropamid, probenazole, kasugamycin, and boscalid.
    Type: Grant
    Filed: December 28, 2013
    Date of Patent: February 2, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: David Ouimette, Richard K. Mann, John Todd Mathieson, Olavo Correa da Silva
  • Patent number: 9241890
    Abstract: The present invention relates to a topical composition, in particular a cosmetic and/or dermatological composition, to be used for preventing and/or treating stretch marks, including, in a physiologically acceptable medium, an effective amount of at least one synthetic polysulfated oligosaccharide having 1 to 4 glycose units, the salts thereof, and/or the derivatives thereof. The invention also relates to a cosmetic method, in particular for treating stretch marks, including at least one step of applying said composition to the skin.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: January 26, 2016
    Assignees: SOCIETE DE DEVELOPPEMENT ET DE RECHERCHE INDUSTRIELLE, LABORATOIRES URGO
    Inventors: Laurent Apert, Marielle Bouschbacher
  • Patent number: 9238670
    Abstract: This disclosure relates generally to aminoglycoside derivatives of Formula (I) as described herein. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating bacterial infections by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 19, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Anthony J. Ricci, Robert J. Greenhouse, Alan G. Cheng
  • Patent number: 9233117
    Abstract: Methods for safe and effective treatment of inflammatory lesions of rosacea in a subject are described. The methods involve once daily topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. It has been demonstrated that once daily topical treatment with ivermectin is significantly superior than twice-daily topical treatment with metronidazole in reducing inflammatory lesion counts.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 12, 2016
    Assignee: Galderma S. A.
    Inventors: Jean Jacovella, Jean-Paul Chappuis, Nathalie Sordello Wagner, Michael Graeber, Alexandre Kaoukhov, Laurence Salin, Michel Poncet, Philippe Briantais, Khaled Benkali
  • Patent number: 9233118
    Abstract: Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an affected skin area a topical composition containing ivermectin and a pharmaceutically acceptable carrier. Treatment with ivermectin represents an innovative therapy that is more robust and effective than the conventional treatments.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 12, 2016
    Assignee: Galderma S.A.
    Inventors: Jean Jacovella, Jean-Paul Chappuis, Alexandre Kaoukhov, Michael Graeber, Michel Poncet, Philippe Briantais, Laurence Salin
  • Patent number: 9220719
    Abstract: This invention provides a single-dose oral formulation of spinosad for the extended control of a C. felis infestation on a cat at a predictable dose of spinosad that is suitable for administration once every 30 days (i.e., one month). The invention also provides methods of using the formulation of spinosad.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: December 29, 2015
    Assignee: ELI LILLY AND COMPANY
    Inventors: Kari Lynette Riggs, Daniel Earl Snyder, Michelle Leigh Totten
  • Patent number: 9221862
    Abstract: An anti-infective drug-macrolide derivate, preparation and uses thereof. Macrolide derivate, namely erythromycin ethylsuccinate crystalline hydrate. Preparation of erythromycin ethylsuccinate crystalline hydrate medicaments for the treatment and prevention of human or animal infectious diseases caused by Gram-positive or negative bacteria.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: December 29, 2015
    Inventor: Li Liu
  • Patent number: 9216187
    Abstract: A soy saponin composition is provided high bodily absorption characteristics. In an embodiment, a soyasapogenol composition comprises soyasapogenol B and 3-O-D-glucuronopyranosyl soyasapogenol B. The weight ratio (B/A) of the 3-O-D-glucuronopyranosyl soyasapogenol B to the soyasapogenol B is in the range of 0.001-10. The composition can be produced by partial decomposition of a sugar chain residue of a soy saponin B group glycoside utilizing an acid.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: December 22, 2015
    Assignee: J-Oil Mills, Inc.
    Inventors: Shuichi Kamo, Toshiro Sato, Shunsuke Suzuki
  • Patent number: 9211305
    Abstract: The invention relates to a composition of glycosaminoglycans for the treatment of diabetic foot ulcer, it specifically relates to low molecular weight heparins (LMWHs) and very low molecular weight heparins (VLMWHs) in the treatment of chronic ulcers, particularly of diabetic foot ulcers, and more specifically in the manufacture of a medicinal product for the treatment of chronic ulcers, and particularly diabetic foot ulcers and pressure ulcers.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: December 15, 2015
    Assignee: Laboratories Farmaceuticos Roui, S.A.
    Inventors: Ivan Lopez-Belmonte Encina, Maria De Los Angeles Canales Mayordomo, Elena Cebadera Miranda
  • Patent number: 9212201
    Abstract: In certain aspects, the present disclosure provides for novel, water-soluble polyene macrolides and salts or solvates thereof and methods of making the water-soluble polyene macrolides. Also provided are compositions and methods for inhibiting, preventing, and/or treating fungal and parasitic diseases in a subject.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: December 15, 2015
    Assignee: ACEA Biotech, Inc.
    Inventor: Josefino B. Tunac
  • Patent number: 9206407
    Abstract: The present disclosure provides a sophorolipid composition that can be used for inducing protein expression in a fermentation host. The sophorolipid composition described herein can be prepared from a natural sophorolipid mixture. Acid treatment of the natural sophorolipid mixture results in a mixture of monoacetylated, deacetylated, and/or diacetylated sophorolipids. The chemically modified sophorolipid composition, or isolated components of the chemically modified sophorolipid composition, can be used as inducers for protein production in filamentous fungi.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: December 8, 2015
    Assignee: Sophoro Biotechnologies, LLC
    Inventor: Tom Tao Huang
  • Patent number: 9206214
    Abstract: The inventions discloses a process for preparation of compounds of Formula (IX), Wherein, R is C1-C6 alkyl, R1 is hydrogen or a hydroxyl protecting group, and R2 is hydrogen or fluorine.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: December 8, 2015
    Assignee: Wockhardt Ltd.
    Inventors: Vijaykumar Jagdishwar Patil, Satish Birajdar, Bharat Dond, Bharat Kalidas Trivedi
  • Patent number: 9200026
    Abstract: Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: December 1, 2015
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Chang-Hsing Liang, Jonathan Duffield, Alex Romero, Yu-Hung Chiu, Steve Sucheck, Kenneth Marby, Youe-Kong Shue, Yoshitaka Ichikawa, Chan-Kou Hwang, David Rabuka, Sulan Yao
  • Patent number: 9198862
    Abstract: Disclosed herein is a dispersible tablet composition including a pharmacologically active ingredient and at least one excipient that reduces the sedimentation rate of the active ingredient and a process for preparing the same.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: December 1, 2015
    Assignee: Rubicon Research Private Limited
    Inventors: Pratibha Sudhir Pilgaonkar, Maharukh Tehmasp Rustomjee, Anilkumar Surendrakumar Gandhi, Pradnya Bagde, Varsha Barve
  • Patent number: 9198430
    Abstract: This invention relates to a veterinary antiparasitic solubilized composition including a macrocyclic lactone or a pharmaceutically equivalent salt thereof, and levamisole or a pharmaceutically equivalent salt thereof, characterized in that the pH of the composition is in the range of 2.0 to 5.0 and wherein the composition includes at least one surfactant and at least one antioxidant.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: December 1, 2015
    Assignee: BAYER NEW ZEALAND LIMITED
    Inventors: Wayne Frederick Leech, Fadil Al Alawi, Karthigeyan Nanjan
  • Patent number: 9187513
    Abstract: A compound of the formula (1) wherein R1 is a group removable by hydrogenolysis, and wherein R2 is OH or R2 is —NHR3 wherein R3 is a group removable by hydrogenolysis. The compound can be made from fructose by a Heyns-rearrangement. The compound can be used then to make free D-mannosamine or its salts, D-mannosamine building blocks and mannosamine containing oligo- or polysaccharides, N-acetyl-D-mannosamine and its hydrates and solvates, neuraminic acid derivatives, and viral neuraminidase inhibitors.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: November 17, 2015
    Assignee: GLYCOM A/S
    Inventors: Ioannis Vrasidas, Gyula Dekany, Ågnes Jánosi, Markus Hederos, Christoph Röhrig
  • Patent number: 9175031
    Abstract: The invention relates to ketolide compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, hydrates, polymorphs and stereoisomers having antimicrobial activity. The invention also provides pharmaceutical compositions containing the compounds of invention and methods of treating or preventing microbial infections with the compounds of invention, wherein, T is —C*H(R1)—P-Q; R1 is hydrogen; unsubstituted or substituted lower alkyl, cycloalkyl or aryl; P is heteroaryl ring; Q is unsubstituted or substituted aryl or heteroaryl ring; and P is attached to Q via carbon-carbon link; and R3 is hydrogen or fluorine, With the provision that when R1 is hydrogen, R3 is fluorine.
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: November 3, 2015
    Assignee: WOCKHARDT LIMITED
    Inventors: Bharat Trivedi, Prasad Deshpande, Ravikumar Tadiparthi, Sunil Gupta, Santosh Diwakar, Shivaji Pawar, Vijay Patil, Deepak Dekhane, Mahesh Patel, Satish Bhavsar, Amit Mishra, Manish Solanki, Mohammad Jafri, Sachin Bhagwat
  • Patent number: 9173892
    Abstract: Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: November 3, 2015
    Assignees: Universite Nice Sophia Antipolis, Centre National De La Recherche Scientifique, Institut National De La Sante De La Recherche Medicale
    Inventors: Rachid Benhida, Patrick Auberger, Vincent Malnuit, Mohsine Driowya, Alexandre Puissant, Guillaume Robert
  • Patent number: 9167822
    Abstract: The present invention relates to new antifungal compositions and their use in the treatment of agricultural products.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: October 27, 2015
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jacobus Stark, Angelique De Rijk