Patents Examined by Emily Cordas
  • Corn blends that include high oil corn and methods of making one or more biochemicals using high oil corn or corn blends that include high oil corn
    Patent number: 10889837
    Abstract: The present invention relates to using high oil corn to make a biochemical such as ethanol. More particularly, the invention relates to methods of making a biochemical using relatively low temperature saccharification followed by fermentation or simultaneous saccharification and fermentation of high oil corn.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: January 12, 2021
    Assignee: POET Research, Inc.
    Inventors: Stephen M. Lewis, John Kenneth Grearson, Neelakantam V. Narendranath, Francis Michael Swain, Brett Yerdon, Camille Kelly Nelson
  • Whole blood separation sampling apparatus
    Patent number: 10883977
    Abstract: The present invention provides systems, devices, kits, and methods for separating blood plasma or serum from whole blood. The present invention further provides systems, devices, and methods for separating a volume of blood plasma or serum from whole blood.
    Type: Grant
    Filed: December 20, 2014
    Date of Patent: January 5, 2021
    Assignee: Spot Bioscience, LLC
    Inventors: Jason Wright, James Hill
  • Cell culture kit, screening method, and method of manufacturing cell culture kit
    Patent number: 10836996
    Abstract: To provide a cell culture kit including cultured living cells of various donors, and a manufacturing method thereof. The cell culture kit includes a culture plate and living cells cultured thereon. The culture plate includes a plurality of microchambers (33) and living cells derived from various donors are adhered to surfaces of the plurality of microchambers (33). Specifically, living cells D1, D2, and D3 derived from various donors are adhered to the plurality of microchambers (33). In each microchamber (33), living cells derived from one donor or living cells derived from various donors may be cultured. The living cells derived from various donors are adhered and cultured in the cell culture kit as a whole, which makes it possible to provide a cell culture kit to conduct a test using cells derived from various donors.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: November 17, 2020
    Assignees: Corning Incorporated, Public University Corporation Yokohama City University
    Inventors: Yoko Itchoda, Go Tazaki, Motohiro Fukuda, Hitoshi Tsuruta, Hideki Taniguchi
  • Lipid membrane structure, lipid-membrane-structure-immobilization carrier, and method of fusing vesicles
    Patent number: 10807061
    Abstract: In methods of separating, moving, and detecting a vesicle of the present invention, either a vesicular-shaped lipid membrane structure containing a membrane-fusogenic lipid capable of being fused with a vesicle having a lipid bilayer membrane, or a lipid-membrane-structure-immobilization carrier, in which a lipid membrane structure containing a membrane-fusogenic lipid capable of being fused with a vesicle having a lipid bilayer membrane is immobilized on a carrier, is brought into contact with a sample containing the vesicle such that membrane fusion occurs between the lipid membrane structure and the vesicle.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: October 20, 2020
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Takumi Hirase, Rii Morimura, Masato Nakayama
  • Erythrocyte sedimentation inhibitor
    Patent number: 10788502
    Abstract: The present invention addresses a problem in which, when examining blood properties in measurements of thrombus formation capacity and platelet function or the like, measurement data is changed as a result of sedimentation of blood in reservoirs during measurement. An erythrocyte membrane ion transport inhibitor, such as disodium 4,4?-dinitrostilbene-2,2?-disulfonate (DNDS) or 4,4?-diisothiocyanatostilbene-2,2?-disulfonic acid (DIDS), is used to inhibit erythrocyte sedimentation, and accurate measurement data is obtained.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: September 29, 2020
    Assignee: FUJIMORI KOGYO CO., LTD.
    Inventors: Kazuya Hosokawa, Tomoko Wada
  • Method of producing sugar liquid
    Patent number: 10781466
    Abstract: A method of producing a sugar liquid includes: (A) reacting mannanase with a liquid component obtained by hydrolysis treatment of woody biomass to obtain a saccharified liquid; and (B) filtering the saccharified liquid in Step (A) through a microfiltration membrane and/or ultrafiltration membrane to collect a sugar liquid from a permeate side.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: September 22, 2020
    Assignee: Toray Industries, Inc.
    Inventors: Atsushi Minamino, Yuka Asahi, Hiroyuki Kurihara, Jumpei Kishimoto, Masashi Higasa, Katsushige Yamada
  • Method for rapid testing allergy
    Patent number: 10746722
    Abstract: The present invention provides a method for testing an allergy capable of rapidly and highly accurately testing an allergic reaction. The method can determine whether or not a patient has an allergy or whether or not an agent that may be allergenic to a patient has an allergenicity (an allergic reactivity) in the patient. The method may comprise the steps of causing migration of leukocytes separated from a healthy human or cells of an established cell line with a chemotactic factor contained in a sample such as body fluid or blood of the patient to be tested or a sample stimulated with the agent that may be allergenic to the patient and analyzing the cell kinetics such as migration velocity, migration distance, and migration direction.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: August 18, 2020
    Inventor: Hirotomo Shibaguchi
  • Method for rapid testing allergy
    Patent number: 10746721
    Abstract: The present invention provides a method for testing an allergy capable of rapidly and highly accurately testing an allergic reaction. The method can determine whether or not a patient has an allergy or whether or not an agent that may be allergenic to a patient has an allergenicity (an allergic reactivity) in the patient. The method may comprise the steps of causing migration of leukocytes separated from a healthy human or cells of an established cell line with a chemotactic factor contained in a sample such as body fluid or blood of the patient to be tested or a sample stimulated with the agent that may be allergenic to the patient and analyzing the cell kinetics such as migration velocity, migration distance, and migration direction.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: August 18, 2020
    Inventor: Hirotomo Shibaguchi
  • Process for implementing in vitro spermatogenesis and associated device
    Patent number: 10723999
    Abstract: The present invention relates to a process for in vitro spermatogenesis from male germinal tissue comprising conducting maturation of testicular tissue comprising germ cells in a bioreactor which is made of a biomaterial and comprises at least one cavity wherein the germinal tissue is placed, and recovering elongated spermatids and/or spermatozoa.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: July 28, 2020
    Assignees: KALLISTEM, UNIVERSITÉ CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), ECOLE NORMALE SUPERIEURE DE LYON
    Inventors: Marie-Hélène Perrard, Philippe Durand, Laurent David
  • Methods for the production and use of mycelial liquid tissue culture
    Patent number: 10709157
    Abstract: A method enhancing the taste of a food product, which includes the steps of culturing a mycelial liquid tissue culture in a media, collecting a mycelium-free portion of the mycelial liquid tissue culture, e.g., the supernatant fluid of the mycelial liquid tissue culture, and adding the collected supernatant fluid to a food product in an amount sufficient to enhance the food product's taste. The mycelial liquid tissue culture may include C. sinensis, and the culture step may be carried out for between about one and sixty days. The food products include non-nutritive sweeteners, alcoholic beverages, teas, coffees, bitter tasting foods such as cranberry, grapefruit, pomegranate, and coconut, as well as dietary supplements, food additives, pharmaceuticals, and nutraceuticals. The present invention also includes compositions of food products in combination with mycelium-free fluids.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: July 14, 2020
    Assignee: MycoTechnology, Inc.
    Inventors: James Patrick Langan, Brooks John Kelly, Huntington Davis, Bhupendra Kumar Soni
  • Herbaceous selenium-enriched SOD non-antibiotic feed additive and method of use thereof
    Patent number: 10709155
    Abstract: A non-antibiotic feed additive including various ingredients, including selenium and superoxide dismutase (SOD). Also provided is a feed including the feed additive.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: July 14, 2020
    Assignee: NE PLUS ENTERPRISES, LLC
    Inventors: Lijun Zhu, Lijun Qing, Qing Yang, Xiang Feng, Wuping Chen, Sixiang Chen
  • Lactic acid bacterium
    Patent number: 10675311
    Abstract: This invention provides lactic acid bacteria that have one or more effects selected from among fatigue-ameliorating effect, blood circulation-improving effect, stool odor-reducing effect, and growth-promoting effect and that can be used with high safety. This invention further provides a pharmaceutical preparation comprising, as an active ingredient, lactic acid bacteria that have one or more effects selected from among fatigue-ameliorating effect, blood circulation-improving effect, stool odor-reducing effect, and growth-promoting effect. According to the invention, novel lactic acid bacteria belonging to the Enterococcus faecium species having particular mycological properties and exhibiting viability of 40% or higher when freeze-dried in the absence of a dispersion medium and viability of 80% or higher in a probiotic preparation when stored at 40° C.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: June 9, 2020
    Assignee: KANEKA CORPORATION
    Inventors: Airo Tategaki, Taizo Kawabe, Hozumi Tanaka
  • Adherent cell culture method
    Patent number: 10655107
    Abstract: Provided are a method capable of evaluating adherent cells under an environment similar to an in vivo environment by a culture method similar to a two-dimensional culture, and applications thereof. An adherent cell culture method uses, as a culture chamber (10), a chamber in which two or more culture spaces each having an equivalent diameter (D) that is 1 to 5 times the diameter of a desired spheroid and each having a height (H) that is 0.3 to 5 times the equivalent diameter are arranged and a surface of each of the culture spaces has a water contact angle of 45 degrees or less. Spheroids of adherent cells are cultured in the respective culture spaces (11) arranged in the culture chamber (10).
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 19, 2020
    Assignee: Corning Incorporated
    Inventors: Yoko Ejiri, Satoru Ayano, Masaya Hosoda, Go Tazaki
  • Selective enrichment media and uses thereof
    Patent number: 10619130
    Abstract: Selective enrichment media and methods for selectively growing and detecting Salmonella spp. and/or Shiga toxin-producing E. coli. The media may comprise a carbon and nitrogen source, an inorganic salt, a fermentable sugar, one or more selective agents, and an efflux pump inhibitor. Various selective agents include sulfa drugs, surfactants, aminocoumarins, cycloheximide, supravital stains, ascorbic acid, bromobenzoic acid, myricetin, nitrofurantoin, rifamycins, polyketides, and oxazolidinones. Various efflux pump inhibitors include arylpiperazines, such as 1-(1-naphthylmethyl)piperazine, and quinoline derivatives, such as 4-chloroquinoline. Methods of selectively growing and detecting Salmonella and/or Shiga toxin-producing E. coli are provided.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: April 14, 2020
    Assignee: PARADIGM DIAGNOSTICS, INC.
    Inventor: Alan D Olstein
  • Treating rotator cuff conditions
    Patent number: 10610570
    Abstract: This document provides methods and materials related to treating rotator cuff conditions (e.g., rotator cuff tendonitis or rotator cuff injuries such as partial rotator cuff tears). For example, methods and materials for using BMP-5 polypeptides to treat rotator cuff conditions as well as methods and materials for using inhibitors of SIRT6, SIRT7, and/or HDAC10 polypeptide expression or activity to treat rotator cuff conditions are provided.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: April 7, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Scott M. Riester, John W. Sperling, Andre J. van Wijnen
  • Plant derived cell culture material
    Patent number: 10612003
    Abstract: The present invention relates material that is useful in culturing and transferring cells as well as delivering cells. The material comprises plant derived cellulose nanofibers or derivatives thereof, wherein the cellulose nanofibers are in a form of a hydrogel or membrane. The invention also provides methods for producing these materials and compositions and uses thereof.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: April 7, 2020
    Assignee: UPM-KYMMENE CORPORATION
    Inventors: Marjo Yliperttula, Patrick Laurén, Madhushree Bhattacharya, Yanru Lou, Antti Laukkanen
  • Brown fat cell compositions and methods
    Patent number: 10597638
    Abstract: Methods of developing and using cell lines, such as stem cell lines, for therapeutic or cosmetic use. In one embodiment the cell lines are used to treat a wide range of degenerative and metabolic disorders including, but not limited to, obesity, diabetes, hypertension, and cardiac deficiency. Also described are methods of using such cell lines to screen for compounds that play a role in regulating a variety of processes.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: March 24, 2020
    Assignee: BIORESTORATIVE THERAPIES, INC.
    Inventors: Francisco Javier Silva, Mark Weinreb, Amit N. Patel, David A. Bull
  • Cohesive thin liquids to promote safe swallowing in dysphagic patients
    Patent number: 10582722
    Abstract: Nutritional products having improved cohesiveness for promoting safer swallowing of food boluses for patients having swallowing conditions are provided as well as methods of making and using such products. The nutritional products may include nutritional compositions and high molecular weight, water-soluble polymers such that the nutritional products have extensional viscosities that provide improved cohesiveness to the nutritional products. Methods of administering such nutritional products to patients having impaired swallowing ability and/or dysphagia are also provided.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: March 10, 2020
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Adam Burbidge, Jan Engmann, Simina Popa Nita
  • Extensional viscosity to promote safe swallowing of food boluses
    Patent number: 10583097
    Abstract: Nutritional products having improved cohesiveness of food boluses and methods of making and using same are provided. The nutritional products may include nutritional compositions and high molecular weight, water-soluble polymers such that the nutritional products have extensional viscosities that provide improved cohesiveness to the nutritional products and Trouton ratios of at least 6. Methods of administering such nutritional products to patients having impaired swallowing ability and/or dysphagia are also provided.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: March 10, 2020
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Adam Stewart Burbidge, Jan Engmann, Simina Popa Nita
  • Methods and devices for analysis of defined multicellular combinations
    Patent number: 10578633
    Abstract: Methods for cell analysis are provided, comprising cell capturing, characterization, transport, and culture. In an exemplary method individual cells (and/or cellular units) are flowed into a microfluidic channel, the channel is partitioned into a plurality of contiguous segments, capturing at least one cell in at least one segment, A characteristic of one or more captured cells is determined and the cell(s) and combinations of cells are transported to specified cell holding chamber(s) based on the determined characteristic(s). Also provided are devices and systems for cell analysis.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 3, 2020
    Assignee: FLUIDIGM CORPORATION
    Inventors: Jason A. A. West, Brian Fowler