Patents Examined by Emily R. Berkeley
-
Determination of the distribution of reactive and non-reactive sulfur in petroleum and its fractions
Patent number: 10048244Abstract: A method to determine the distribution of non-reactive sulfur compounds and reactive sulfur compounds in petroleum samples by separating non-reactive sulfur compounds from reactive sulfur compounds in a petroleum composition includes the step of contacting the petroleum composition with a Ag-containing cation exchange media. The petroleum composition and the Ag-containing cation exchange media are contacted with a non-reactive sulfur compound solvent capable of eluting the non-reactive sulfur compounds in the presence of the Ag-containing cation exchange media and incapable of eluting the reactive sulfur compounds in the presence of the Ag-containing cation exchange media at the conditions of the exchange. The non-reactive sulfur compounds are eluted from the media with the non-reactive sulfur compound solvent to provide a first fraction. The amount of non-reactive sulfur compounds in the first fraction is then determined.Type: GrantFiled: March 13, 2014Date of Patent: August 14, 2018Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: Ryan P. Rodgers, Winston K. Robbins, Vladislav V. Lobodin -
Patent number: 10029825Abstract: A material for use in vacuum bagging a component. The material includes a compound sensitive to moisture, such that an exposure of the compound to moisture or wetting causes a physical and/or chemical change in the compound that is visually detectable in the cover material. A method of leak detection during vacuum bagging involves the steps of: arranging a component in a vacuum bagging assembly, such as to form a fiber-reinforced plastic component; arranging a material according to the invention in the vacuum bagging assembly such that the compound sensitive to wetting or moisture is under, or on an inner side of, a sealing film or vacuum bag of the assembly; applying a vacuum to the vacuum bagging assembly to evacuate a space containing the component and sealed by the sealing film or vacuum bag; and wetting an outer surface of the sealing film or vacuum bag.Type: GrantFiled: June 3, 2013Date of Patent: July 24, 2018Assignee: AIRBUS OPERATIONS GMBHInventors: Hauke Seegel, Claus Fastert, Paulin Fideu
-
Patent number: 10024803Abstract: A method for determining an analyte of a liquid sample in a cuvette includes providing a cuvette, a reagent, a barcode, an icon on the cuvette and a liquid analysis device comprising a photometer, a rotation device, a camera, a calibration data memory storing first calibration data, and an input device which manually inputs second calibration data. The cuvette is inserted into the liquid analysis device and is rotated to align the icon with the camera. The icon is read with the camera and the icon read compared with an icon model stored in the liquid analysis device to determine whether it corresponds thereto. The liquid sample is subjected to photometry based on the first calibration data if the icon read corresponds to the icon model. If not, the input apparatus is activated and the liquid sample is subjected to photometry on the basis of the second calibration data.Type: GrantFiled: August 9, 2011Date of Patent: July 17, 2018Assignee: HACH LANGE GMBHInventors: Markus Lenhard, Manfred Battefeld, Bernd Gassner, Baas De Heij, Clemens Hanschke
-
Patent number: 10024866Abstract: A device for the microstructured grafting of proteins onto a substrate, comprising a substrate (7), a layer comprising a polyethylene glycol and being placed on the substrate, a matrix (10) of micromirrors for propagating the light in a first pattern and for replacing the first pattern with a second pattern. The microfluidic circuit is filled so as to bring a first aqueous solution containing a first protein into contact with the layer, a first microstructured image of the first pattern being formed on the layer to photoprint the first protein on the layer, and the microfluidic circuit is adapted to replace the first aqueous solution with a second aqueous solution containing a second protein so as to bring the second aqueous solution and the layer into contact, the first pattern being replaced with the second pattern in order to photoprint the second protein on the layer.Type: GrantFiled: March 14, 2013Date of Patent: July 17, 2018Assignees: ALVEOLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, Universite de Bordeaux SegalenInventors: Vincent Studer, Ammar Azioune
-
Patent number: 10018543Abstract: A method includes supplying a reagent to a column, where the column is configured to purify an element from a sample matrix for isotopic analysis. The method also includes loading the column with the sample matrix, and supplying a second reagent to collect the element retained by the column. The method further includes loading the column with a second sample mixture, and collecting an element from the second sample mixture retained by the column. A column configured to separate an element from a sample matrix for isotopic analysis includes a resin configured to retain the element. The column also includes a first frit disposed of a first end of the column and a second frit disposed of a second end of the column. The column is configured to receive a first reagent in a first flow direction and a second reagent in a second flow direction different from the first flow direction.Type: GrantFiled: June 5, 2014Date of Patent: July 10, 2018Assignee: ELEMENTAL SCIENTIFIC, INC.Inventors: Daniel R. Wiederin, Paul Field
-
Patent number: 10001431Abstract: A device (1) for extracting an extraction material, in particular for solid-phase micro-extraction, comprises an extractor (130) and a tip (100) for penetrating a separating layer, wherein the extractor (130) is connected to the tip (100). In a method for extracting an extraction material from a container with an extraction device (1), a separating layer of the container is penetrated by a tip (100) of an extractor (130), and the extraction material is extracted.Type: GrantFiled: February 4, 2014Date of Patent: June 19, 2018Assignee: CTC ANALYTICS AGInventors: Kai Heinrich Schueler, Christophe Schillig
-
Patent number: 9994713Abstract: Fluorescent Schiff base compounds comprising a xanthene dye based moiety and an alkyl imidazole moiety. Methods of assessing these fluorescent Schiff base compounds as fluorescent probes for metal ions in Cu2+ chemosensing applications, methods of preparing the fluorescent Schiff base compounds and methods of detecting Cu2+ ions with the same are also provided.Type: GrantFiled: March 28, 2016Date of Patent: June 12, 2018Assignee: King Fahd University of Petroleum and MineralsInventor: Aasif Helal
-
Patent number: 9988664Abstract: A bioparticle collection device and an aerosol collection system. The bioparticle collection device includes a collection medium including a plurality of fibers formed into a fiber mat and configured to collect bioparticles thereon, and includes a viability enhancing material provider disposed in a vicinity of the plurality of fibers and configured to provide a viability enhancing material to the collected bioparticles to maintain viability of the bioparticles collected by the fiber mat. The aerosol collection system includes an aerosol pumping device configured to entrain particles in an gas stream, an aerosol saturation device configured to saturate the particles in the gas stream with a biocompatible liquid, and an aerosol collection medium downstream from the aerosol saturation device and including a plurality of fibers formed into a fiber mat for collection of the saturated aerosol particles.Type: GrantFiled: November 24, 2015Date of Patent: June 5, 2018Assignee: Research Triangle InstituteInventors: David Samuel Ensor, Howard Jerome Walls, Karin K Foarde
-
Patent number: 9983187Abstract: The present invention is a system for the extraction and quantification of tetraprotic naphthenic acids present in oils, precursors of the formation of calcium naphthenates, which are potential formers of deposits, causing of damage to pieces of equipment used in the oil production industry.Type: GrantFiled: September 22, 2015Date of Patent: May 29, 2018Assignee: PETROLEO BRASILEIRO S.A.-PETROBRASInventors: Flávio Cortiñas Albuquerque, Rafael dos Santos Nascimento de Brito, Marcele Abreu Lopes
-
Patent number: 9983105Abstract: Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved.Type: GrantFiled: June 22, 2017Date of Patent: May 29, 2018Assignee: Biosurfit, S.A.Inventors: Carlota Albuquerque, Tânia Tenreiro, Nuno Reis, João Garcia Da Fonseca, Ricardo Marques Caleiro Cabeça
-
Patent number: 9983185Abstract: A chemosensing hydrogel is provided that undergoes a colorimetric reaction in response to the detection of a biogenic amine vapor, such as a biogenic amine vapor that is a by-product resulting from food spoilage. In an embodiment, an apparatus for detection of biogenic amines, is provided that includes a hydrogel having a bimetallic iron(II)-iron(III) complex disposed within the hydrogel, wherein the hydrogel is configured to change from a first color to a second color in response to exposure to a biogenic amine.Type: GrantFiled: February 1, 2016Date of Patent: May 29, 2018Assignee: CITY UNIVERSITY OF HONG KONGInventor: Hon-Wah Lam
-
Patent number: 9975913Abstract: The present invention relates to a method for in-gel visual detection and quantitative detection of proteins in activity based protein profiling (ABPP) using horseradish peroxidase mimic FeIII-TAML complex of ligand as a catalytic probe. The invention further relates to kit comprising compounds of formula (I) and method for the detection of bioanalytes using kit comprising compounds of formula (I).Type: GrantFiled: July 5, 2016Date of Patent: May 22, 2018Assignee: Council of Scientific & Industrial ResearchInventors: Sayam Sen Gupta, Sushma Kumari, Chakadola Panda
-
Patent number: 9962692Abstract: In one aspect, the present invention provides methods, devices, and systems for ensuring that multiple components of a mixture are fully mixed in a continuous flow microfluidic system while ensuring that mixing between segments flowing through the chip is minimized. In some embodiments, the present invention includes mixing fluids in a droplet maintained at the tip of a pipette before the mixture is introduced to the microfluidic device. In another aspect, the present invention provides a pipette tip having a ratio of an outside diameter to an inside diameter that provides sufficient surface area for a droplet comprising up to the entire volume of the liquid to suspend from the pipette tip intact. In yet another aspect, the present invention provides methods, devices, and systems for delivering a reaction mixture to a microfluidic chip comprising a docking receptacle, an access tube and a reservoir.Type: GrantFiled: August 31, 2011Date of Patent: May 8, 2018Assignee: Canon U.S. Life Sciences, Inc.Inventors: Ivor T. Knight, Scott Corey, Ben Lane, Conrad Laskowski, Alex Flamm, Brian Murphy
-
Patent number: 9958422Abstract: This disclosure provides methods and devices for quantitating, separating and/or detecting water in a liquid, gas or solid sample comprising one or more chemicals, the method comprising: providing the liquid, gas or solid sample comprising water and the one or more chemicals; and exposing said liquid, gas or solid sample to at least one solid support including at least one dicationic and/or tricationic species of Formula I or II adsorbed, absorbed or immobilized on the solid support.Type: GrantFiled: October 22, 2015Date of Patent: May 1, 2018Assignee: Sigma-Aldrich Co. LLCInventor: Daniel W. Armstrong
-
Patent number: 9958361Abstract: A test device for analyzing fluid samples. The test device includes a planar support member for supporting reagent pads, and a handle attached to, or for attaching to the planar support member. The test device can be treated with a fluid sample by disposing a fluid sample on the reagent pads. The fluid sample can be disposed onto the reagent pads by the handle, or by dipping the test device into the fluid sample.Type: GrantFiled: June 7, 2012Date of Patent: May 1, 2018Assignee: Siemens Healthcare Diagnostics Inc.Inventor: Paul William Cotton
-
Patent number: 9958363Abstract: A method for removing an ionic liquid from an aqueous sample is provided. In some embodiments, the method includes: (a) combining an aqueous sample including an ionic liquid with an ion exchanger composition including an ion exchanger counterion to produce a solution including a fluorous salt of the ionic liquid, where at least one of the ionic liquid and the ion exchanger counterion is fluorinated; (b) contacting the solution with a fluorous affinity material, thereby removing fluorous salt from the solution and producing an aqueous eluate; and (c) collecting the aqueous eluate. In certain embodiments, the method further includes: contacting a cell with an ionic liquid composition to lyse the cell and produce an aqueous sample; and contacting the aqueous sample with a reverse phase substrate, thereby adsorbing proteins and/or lipids of the cell on the substrate. Compositions, kits and systems for practicing the subject methods are also provided.Type: GrantFiled: May 28, 2015Date of Patent: May 1, 2018Assignee: Agilent Technologies, Inc.Inventors: Brian Phillip Smart, Brooks Bond-Watts, James Alexander Apffel, Jr.
-
Patent number: 9952231Abstract: Embodiments of methods and compounds for isolating and detecting lysophosphatidic acids (LPAs) are disclosed. Kits for performing the methods also are disclosed. LPAs are isolated from biological samples by liquid-liquid extraction followed by solid phase extraction. LPA species may be separated by HPLC, and the separated species may be identified and quantified. Also disclosed are embodiments of compounds capable of universally detecting a plurality of LPA species with substantially equivalent sensitivity. Embodiments of the disclosed compounds are useful for determination of total LPA concentration in a sample comprising a plurality of LPA species without separation of individual LPA species.Type: GrantFiled: March 14, 2014Date of Patent: April 24, 2018Assignee: Portland State UniversityInventors: Robert Strongin, Martha Sibrian-Vazquez, Jialu Wang, Lei Wang, Jorge O. Escobedo-Cordova
-
Patent number: 9945761Abstract: In some embodiments, a system may function to transfer samples in a controlled environment. The system may include a sample container configured to convey a sample from a first device to a second device. The first device may be under pressure and the second device may be under vacuum. The second device may include a load chamber which functions to accept the sample from the sample container and a pump chamber coupled to the load chamber. The second device may include a high vacuum pump coupled to the pump chamber and a vacuum pump coupled to the pump chamber through the high vacuum pump in sequence. The second device may include an orifice sized to significantly restrict the flow of fluids through the conduit coupling the pump chamber to the load chamber, wherein the orifice is configured to allow for a transition from a viscous into a molecular flow.Type: GrantFiled: July 29, 2014Date of Patent: April 17, 2018Assignee: Board of Regents of the University of Texas SystemInventor: Hugo Celio
-
Patent number: 9933340Abstract: A method for controlled movement of magnetic carriers in a sample volume for performing immunoassays under weightless or reduced-weight conditions, wherein the magnetic carriers are moved inside the sample volume by means of permanent magnets movably arranged relative to at least one spatial axis of the sample volume.Type: GrantFiled: February 15, 2013Date of Patent: April 3, 2018Assignee: Airbus DS GmbHInventors: Peter Kern, Herbert Backes
-
Patent number: 9933408Abstract: Method for characterizing the hydrocarbon content of a reformate sample stream comprising methane, water, carbon monoxide, ammonia, and hydrogen from a steam-hydrocarbon reforming process. Water and ammonia are removed from the reformate sample stream and the hydrocarbon content of the reformate sample stream depleted in water and ammonia is measured using a chemical component analyzer.Type: GrantFiled: November 10, 2014Date of Patent: April 3, 2018Assignee: Air Products and Chemicals, Inc.Inventor: Matthew H. MacConnell