Abstract: The present invention relates to systems of methods of measuring selected analytes in blood and tissue using Raman spectroscopy to aid in diagnosis. More particularly, Raman spectra are collected and analyzed to measure the concentration of dissolved gases and other analytes of interest in blood. Methods include in vivo transdermal and continuous monitoring as well as in vitro blood analysis.
Type:
Grant
Filed:
March 27, 1995
Date of Patent:
April 1, 1997
Assignee:
Massachusetts Institute of Technology
Inventors:
Andrew J. Berger, James F. Brennan, III, Ramanchandra R. Dasari, Michael S. Feld, Irving Itzkan, Kaz Tanaka, Yang Wang