Abstract: A microorganism resistant to a nicotinic acid analogue, which has a plasmid containing part or whole of a biotin operon; and a process for producing biotin, which comprises culturing a microorganism described above in a medium to produce and accumulate biotin in the medium, and collecting biotin.
Type:
Grant
Filed:
December 14, 1995
Date of Patent:
December 2, 1997
Assignees:
Takeda Chemical Industries, Ltd., Shiseido Company, Limited