Patents Examined by Erid Olson
  • Glycosylation reactions using phenyl(trifluoroethyl)iodonium salts
    Patent number: 9422325
    Abstract: Provided are methods for the preparation of glycosylation products, including those represented by formula I: Sugar-O—R???I comprising the step of combining R?—OH, a glycosyl sulfide glycosyl donor (“thioglycoside donor”), a hypervalent iodine alkyl-transfer activating reagent, and a base. In an embodiment, the hypervalent iodine alkyl-transfer activating reagent is (phenyl(trifluoroethyl)iodonium triflimide).
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: August 23, 2016
    Assignee: Trustees of Tufts College
    Inventors: Clay S. Bennett, An-Hsiang A. Chu