Abstract: Solid phase extraction devices including a plurality of packed nominally aligned capillary-channeled polymeric fibers for use as stationary phase materials are disclosed. A plurality of fibers are packed together in a casing so as to provide good flow characteristics through the fibers and high surface area contact between a sample and the fibers. Different polymer compositions of the fibers permit the “chemical tuning” of the extraction process. The fibers can be physically or chemically derivatized to target specific analytes for separation from a test sample. Use of the fibers allows a wide range of liquid flow rates with very low backpressures. The fibers are easily packed into a micropipette tip or a conduit for use with a fluid flow device such as an aspirator or a pump. The devices can be used for isolation and pre-concentration of analytes from samples, for instance for proteins from buffer solutions or extraction of pollutants from remote locations.
Type:
Grant
Filed:
March 13, 2006
Date of Patent:
June 22, 2010
Inventors:
R. Kenneth Marcus, Philip J. Brown, Igor A. Luzinov, Yonnie S. Wu
Abstract: A cucurbituril-bonded silica gel and its use are provided. The cucurbituril-bonded silica gel is useful for removal of air pollutants or water contaminants, and separation and purification of biological, organic, inorganic, or ionic substances.
Type:
Grant
Filed:
February 11, 2004
Date of Patent:
March 17, 2009
Assignee:
Postech Foundation
Inventors:
Kimoon Kim, Rengarajan Balaji, Dong Hyun Oh, Young Ho Ko, Sang Yong Jon