Patents Examined by Ernst Arnold
  • Patent number: 8808743
    Abstract: Benzonatate resinates of weak acid ion exchange resins having the same distribution of butyl 4-aminobenzoate homologs as exist in the benzonatate listed in the F.D.A. Orange Book as Application No. N011210. These resinates, in simulated gastrointestinal dissolution, release essentially the same distribution of butyl-4 aminobenzoate homologs as exist in the benzonatate listed in the F.D.A. Orange Book as Application No. N011210.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: August 19, 2014
    Inventors: William Wayne Howard, Russell Francis Somma
  • Patent number: 8795741
    Abstract: Disclosed are methods of reducing the risk that a medical treatment comprising inhalation of nitric oxide gas will induce an increase in pulmonary capillary wedge pressure in the patient, leading to pulmonary edema.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: August 5, 2014
    Assignee: INO Therapeutics LLC
    Inventor: James S. Baldassarre
  • Patent number: 8795635
    Abstract: The present invention relates to stable substantially non-aqueous, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum or mixtures thereof, at least one foam agent, at least one propellant, and with and without the addition of an active agent. The formulations may contain a solvent substantially miscible therein. The present invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject in need thereof, comprising administering the above-mentioned compositions to an afflicted target site of said mammalian subject.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: August 5, 2014
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Doron Friedman, Enbal Ziv, Meir Eini, Tal Berman, Jorge Danziger, Rita Keynan, David Schuz
  • Patent number: 8790668
    Abstract: The present invention relates to a personal care composition that contains a rinse-off composition which deposits at least 0.5 ?g/cm2 of shiny particles on the skin. Preferably, the shiny particles are hydrophobically modified interference pigments. The inventors have found that hydrophobically modifying the particles significantly improves the deposition of the particles on skin from rinsable compositions.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: July 29, 2014
    Assignee: The Procter & Gamble Company
    Inventors: Mannie Lee Clapp, Cynthia Ann Garza, Qing Stella, Paul Robert Tanner, Rebecca Ann Taylor
  • Patent number: 8784892
    Abstract: The present invention is directed to the use of an agent selected from ethyl alcohol, isopropyl alcohol or a mixture thereof and a topically acceptable polymeric carrier in the preparation of a composition for the treatment of burns.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: July 22, 2014
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Elka Touitou
  • Patent number: 8784884
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: July 22, 2014
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Patent number: 8771748
    Abstract: Methods are provided for producing compositions, e.g. pastes or clays, which rapidly set into high-strength calcium phosphate products. In the subject methods, dry reactants that include calcium and phosphate sources, as well as a monovalent cation dihydrogen phosphate salt, are combined with a setting fluid and the combined reactants are mixed to produce the settable composition. A feature of the invention is that cements rapidly set into high strength product compositions. Also provided are the compositions themselves as well as kits for preparing the same. The subject methods and compositions produced thereby find use in a variety of applications, including hard tissue repair applications.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: July 8, 2014
    Assignee: Skeletal Kinetics, LLC
    Inventors: Brent R. Constantz, David Delaney, Duran Yetkinler
  • Patent number: 8771739
    Abstract: The present invention provides a pharmaceutical composition of a practically insoluble drug, wherein the composition may be administered with food or without food. The composition may be in the form of a solid dispersion of the practically insoluble drug and a polymer having acidic functional groups, and the composition may in vitro form a suspension.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: July 8, 2014
    Assignee: Mayne Pharma International Pty Ltd
    Inventors: David Hayes, Angelo M. Morella
  • Patent number: 8765719
    Abstract: An object is to provide a novel therapeutic drug for adult T-cell leukemia having an ATL cell specific antitumor effect. The therapeutic drug for adult T-cell leukemia according to the invention is characterized by containing a compound represented by the formula I or a prodrug thereof, wherein R1 is H, OH, an alkoxy group, an acyl group, or a thioacyl group, R2 is an acyl group, a thioacyl group, CONR7R8, or CSNR7R8 (R7 and R8 being each independently H, an alkyl group containing 1 to 3 carbon atoms, or a phenyl group), or R1 and R2 together may form a ring, X1 and X2 may be the same or different and are each —CR3R4—, —SiR3R4— or oxygen, and R3 and R4 may be the same or different and are each an alkyl group containing 1 to 6 carbon atoms.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: July 1, 2014
    Assignee: Kagoshima University
    Inventors: Masanori Baba, Yuichi Hashimoto
  • Patent number: 8758789
    Abstract: The present invention relates to compositions including medium chain peroxycarboxylic acid, methods for making these compositions, and methods for reducing the population of a microorganism. The compositions can include advantageously high levels of the medium chain peroxycarboxylic acid, can be readily made, and/or can exhibit reduced odor.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: June 24, 2014
    Assignee: Ecolab USA Inc.
    Inventors: Victor F. Man, Joshua P. Magnuson, Steven E. Lentsch
  • Patent number: 8758788
    Abstract: Active compound mixtures comprising ipconazole and at least one further fungicidally active compound are highly suitable for protecting industrial materials against colonization and destruction by microorganisms.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: June 24, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Rainer Bruns, Martin Kugler, Thomas Jaetsch
  • Patent number: 8747886
    Abstract: The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk fibroin-based films can be nanoimprinted at room temperature, by locally decreasing the glass transition temperature of the silk film. Such nanoimprinting process increases high throughput and improves potential for incorporation of silk-based photonics into biomedical and other optical devices.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: June 10, 2014
    Assignee: Tufts University
    Inventors: Jason J. Amsden, David L. Kaplan, Fiorenzo Omenetto
  • Patent number: 8748419
    Abstract: Provided are methods of treating obesity and effecting desired weight loss or preventing undesired weight gain by administration of a preferential muscarinic acetylcholine receptor M1 antagonist, optionally with at least one antidepressant other than a selective muscarinic acetylcholine receptor M1 antagonist. The preferential muscarinic acetylcholine receptor M1 antagonist, optionally can be administered with an anti-obesity agent, for example, an anorexiant. The invention also provides for pharmaceutical compositions and kits for administration of at least one selective muscarinic acetylcholine receptor M1 antagonist in combination with at least one antidepressant other than a selective muscarinic acetylcholine receptor M1 antagonist.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: June 10, 2014
    Assignee: Theracos, Inc.
    Inventors: Brian Seed, Jordan Mechanic
  • Patent number: 8748487
    Abstract: Disclosed is a raw material for cosmetic preparations having excellent gloss imparting properties and oxidation stability. Also disclosed is a cosmetic preparation having excellent gloss and feeling of use. The raw material for cosmetic preparations contains an ester compound of (A) benzoic acid, (B) an alcohol selected from the group consisting of neopentyl glycol, dineopentyl glycol, trineopentyl glycol, trimethylolpropane, ditrimethylolpropane, tritrimethylolpropane, dipentaerythritol and tripentaerythritol, and (C) a fatty acid having 3-28 carbon atoms and/or a hydroxycarboxylic acid having 3-28 carbon atoms. The cosmetic preparation contains this raw material for cosmetic preparations.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: June 10, 2014
    Assignee: The Nisshin Oillio Group, Ltd.
    Inventor: Keiji Yasuno
  • Patent number: 8747879
    Abstract: The invention provides a method for fabricating an implantable medical device to increase biocompatibility of the device, the method comprising: heat setting a polymer construct, wherein the polymer construct is at a temperature range of from about Tg to about 0.6(Tm?Tg)+Tg such that the set polymer construct comprises a crystalline structure having crystals at a size less than about 2 microns; and fabricating an implantable medical device from the heat set polymer construct.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: June 10, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale
  • Patent number: 8747878
    Abstract: A method of fabricating an implantable medical device that includes deforming and heating setting a polymer construct, for use in fabricating the device, in a temperature range in which the crystal nucleation rate is greater than the crystal growth rate is disclosed.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: June 10, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale
  • Patent number: 8747912
    Abstract: A drug delivery system for the controlled release of a pharmaceutically-active compound by oral route comprises an intercalate of a layered double hydroxide having, before intercalation, layers of metal hydroxides, and having intercalated therein a pharmaceutically-active compound having at least one anionic group. A preferred layered double hydroxide is one that has layers which comprise [LiAl2(OH)6]+. The drug delivery system has use in the delivery of drugs such as 4-biphenylacetic acid, Diclofenac, Gemfibrozil, Ibuprofen, Naproxen, 2-Propylpentanoic acid and Tolfenamic acid.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 10, 2014
    Assignee: Isis Innovation Limited
    Inventor: Dermot Michael O'Hare
  • Patent number: 8741875
    Abstract: The present invention relates to novel amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: June 3, 2014
    Assignee: Allergan, Inc.
    Inventors: Todd M. Heidelbaugh, Phong X. Nguyen, John Cappiello
  • Patent number: 8741328
    Abstract: The present invention provides a nerve regeneration-inducing tube in which collagen having excellent adhesive property, cell growth property and differentiation inducing property to nerve cells is used as a scaffold for the nerve regeneration. The nerve regeneration-inducing tube is characterized in using the collagen which is made the concentration of sodium chloride contained therein not more than 2.0% by weight or, preferably, 0.1 to 1.5% by weight in a dry state. Purification of collagen is carried out by means of an isoelectric precipitation where the pH is 6.0 or higher and is lower than 10.0.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: June 3, 2014
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Michiko Suzuki, Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara
  • Patent number: 8735436
    Abstract: The present disclosure relates to lipid compounds of the general formula (I): R1-O—C(R2)(R3)-X??(I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be chosen from different substituents; and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide; or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: May 27, 2014
    Assignee: Pronova Biopharma Norge AS
    Inventors: Ragnar Hovland, Anne Kristin Holmeide, Tore Skjæret, Morten Brændvang