Patents Examined by Esther L. Keppkinger
  • Rapamycin assay
    Patent number: 5322772
    Abstract: A competitive protein binding assay for rapamycin and biologically-active metabolites, derivatives and analogues thereof in blood and other biological fluids is disclosed, wherein the binding reagent is a specific rapamycin binding protein either substantially purified from the soluble cytoplasm of target cells of rapamycin action, particularly normal or transformed lymphocytes, freshly collected or in established cell lines, or synthesized by recombinant DNA techniques. Solution phase and solid state assay systems are disclosed.
    Type: Grant
    Filed: April 9, 1991
    Date of Patent: June 21, 1994
    Assignee: Children's Research Institute
    Inventor: Steven J. Soldin