Abstract: The invention relates to human Interleukin-1 Receptor-Associated Protein Kinases (IRAKs), nucleic acids which encode IRAKs and hybridization probes and primers capable of hybridizing with IRAK genes and methods of using the subject compositions; in particular, methods such as IRAK-based in vitro binding assays and phosphorylation assays for screening chemical libraries for lead compounds for pharmacological agents.
Type:
Grant
Filed:
January 16, 1996
Date of Patent:
August 5, 1997
Assignee:
Tularik, Inc.
Inventors:
Zhaodan Cao, David V. Goeddel, Glenn E. Croston