Patents Examined by Everett White
  • Patent number: 8642574
    Abstract: A method of preventing or reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: February 4, 2014
    Assignee: Innovata Limited
    Inventor: Colin Brown
  • Patent number: 8637661
    Abstract: A process is described for the preparation of water-soluble cellulose hydrolysis product. The process comprise admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprises solely of cations and anions and which exists in a liquid state at a temperature at or below 150° C., and in which the anions are selected from halide and cyanate; and treating the resulting solvate or solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25° C.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: January 28, 2014
    Assignee: Petroliam Nasional Berhad
    Inventors: Markus Fanselow, John Holbrey, Kenneth Richard Seddon
  • Patent number: 8637660
    Abstract: A process for the preparation of water-soluble cellulose hydrolysis products, which comprises admixing cellulose with an ionic liquid in which the cellulose has at least some solubility, said ionic liquid state at a temperature at or below 150 -C, and treating the resulting solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25 -C.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: January 28, 2014
    Assignee: Petroliam Nasional Berhad
    Inventors: Markus Fanselow, John Holbrey, Kenneth Richard Seddon
  • Patent number: 8637487
    Abstract: Indigestible oligosaccharides having a molecular weight of 450 Da to 3700 Da are used for the improvement of insulin resistance, the prevention of post-prandial glycaemic dip, and/or the decrease of the post-prandial glucose response of a meal, which is consumed within 72 hours after the consumption of the first product. The oligo-saccharides are especially galacto-oligosaccharides, and are advantageously administered a few hours prior to having the meal.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: January 28, 2014
    Inventors: Hubertus Josephus Maria Van De Heijning, Houkje Bouritius, Katrien Maria Jozefa Van Laere, Robert Johan Joseph Hageman
  • Patent number: 8633166
    Abstract: This present provides kaempferol-3-(2-E,3-Z-di-p-coumaroyl)-rhamnoside, kaempferol-3-(2-Z-3-E-di-p-coumaroyl)-rhamnoside, and kaempferol-3-(2,3-di-Z-p-coumaroyl)-rhamnoside compounds useful as a new class of anti-bacterial agents. These compounds are extracted from Platanus occidentalis. These compounds were found to exhibit anti-bacterial activity against methicillin resistant Staphylococcus aureus (MRSA).
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: January 21, 2014
    Inventors: Mark T. Hamann, Mohamed Ali
  • Patent number: 8633303
    Abstract: Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: January 21, 2014
    Assignee: Glycomimetics, Inc.
    Inventors: John L. Magnani, John T. Patton, Jr., Arun K. Sarkar, Sergei A. Svarovsky, Beat Ernst
  • Patent number: 8629267
    Abstract: A method for producing starch hydrolysate that includes processing in a high shear device a hydrolytic solution having a component selected from the group consisting of acids, hydrolytic enzymes, and combinations thereof, and an aqueous starch solution to produce a dispersion, wherein the high shear device is configured with a rotor and a stator; and transferring the dispersion from the high shear device to a reactor from which a starch hydrolysate product comprising dextrose is removed, wherein the operating temperature within the reactor is maintained at a temperature of less than about 160° C.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: January 14, 2014
    Assignee: H R D Corporation
    Inventors: Abbas Hassan, Ebrahim Bagherzadeh, Rayford G. Anthony, Gregory Borsinger, Aziz Hassan
  • Patent number: 8618067
    Abstract: Disclosed is L-glucose monohydrate and compositions thereof. Also disclosed are methods for making L-glucose monohydrate and compositions thereof. Further disclosed are methods for colonic cleansing using L-sugars, such as L-glucose monohydrate, and compositions and kits useful for colonic cleansing.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: December 31, 2013
    Assignee: Aptalis Pharma US, Inc.
    Inventors: Michael Caswell, Edward Delaney, Mohammad Rahman
  • Patent number: 8575333
    Abstract: The present invention relates to a novel family of alkylated halogenated di- and trisaccharides which exhibit pharmaceutical efficacy in the areas of permeation enhancers, anti-microbial effects, anti-fugal effects, facilitation of diagnostic procedures. The invention further includes methods of treatment and diagnostic kits.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: November 5, 2013
    Inventor: Bahram Memarzadeh
  • Patent number: 8557968
    Abstract: The invention concerns novel biotinylated hexadecasaccharides of general formula (I) wherein: Biot is a biotin derivative; R, R1 and R2, represent independently of one another a C1-C6 alkoxy or and —OSO3; R3 represents a C1-C6 alkoxy or an —OSO3, or R3 constitutes a —O—CH2— bridge; Pe represents a saccharide concatenation; as well as their pharmaceutically acceptable salts, and their use as medicines.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 15, 2013
    Assignee: Sanofi
    Inventors: Philippe Duchaussoy, Jean Pascal Herault, Jean Marc Herbert, Maurice Petitou, Pierre Savi
  • Patent number: 8551974
    Abstract: Ophthalmic compositions are provided that include a lubricant, a deturgescent agent, a glycosaminoglycan, and water. Methods of using the ophthalmic compositions are also provided.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: October 8, 2013
    Inventor: Richard L. Lindstrom
  • Patent number: 8552164
    Abstract: The invention relates to a novel method for production of nanofibrillar chitin, sustainable from an industrial manufacturing standpoint and suitable for producing chitin nanofibrils having improved properties and free from less crystalline components. The invention also relates to novel chitin nanofibrils obtained with said method and characterized by an increased dispersibility in aqueous media. The invention further relates to uses of nanofibrils in pastes and aqueous gels useful for topical on-skin application, to the manufacturing of materials of biomedical interest, as well as to the deposition of chitin nanofibrils on coating surfaces or the incorporation of the same inside of items like, e.g., fibers and fabrics of any Origin, natural as well as synthetic or mixed ones.
    Type: Grant
    Filed: November 23, 2006
    Date of Patent: October 8, 2013
    Assignee: Mavi Sud S.r.l.
    Inventors: Pierfrancesco Morganti, Corrado Muzzarelli
  • Patent number: 8541571
    Abstract: The invention is directed to a simple and new method for the homogeneous synthesis of cellulose ethers. Ionic liquids are not only used as solvent, but also as reaction media for the homogeneous etherification of cellulose. The dissolved cellulose is treated with the etherification agent in the absence of organic and/or inorganic bases and in the absence and/or in the presence of moderate amounts of water. The obtained cellulose ethers show new distributions of substitution on the polymer chain, resulting in new properties and applications.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: September 24, 2013
    Assignee: SE Tylose GmbH & Co. KG
    Inventors: Eugen Moellmann, Thomas Heinze, Tim Liebert, Sarah Koehler
  • Patent number: 8541392
    Abstract: The present invention relates generally to a method of blunting the postprandial glycemic response in a human by feeding an induced viscosity fiber system. The invention also relates to an induced viscosity fiber system and the liquid products that incorporate the induced viscosity fiber system. Further, the invention relates to a method of incorporating soluble fiber into a liquid product without the typical negative organoleptic or physical stability issues. The invention also relates to a method of inducing the feeling of fullness and satiety by feeding the induced viscosity fiber system.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: September 24, 2013
    Assignee: Abbott Laboratories
    Inventors: Bryan W. Wolf, Bruce B. Blidner, Keith A. Garleb, Chron-Si Lai, Timothy W. Schenz
  • Patent number: 8536317
    Abstract: A process for producing a polysaccharide sponge comprises the steps of (A) freezing a photoreactive polysaccharide solution, and (B) irradiating the frozen photoreactive polysaccharide solution with light to crosslink the photoreactive polysaccharide, thereby obtaining the polysaccharide sponge. The process includes simplified steps requiring no removal of solvent, and has such an advantage that impurities are easily removed therefrom.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: September 17, 2013
    Assignee: Seikagaku Corporation
    Inventor: Tomoya Sato
  • Patent number: 8530450
    Abstract: Disclosed are acid polysaccharides characterized by the concomitant presence of alcohol groups esterified with butyric and formic acids.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: September 10, 2013
    Assignee: Sigea S.R.L.
    Inventors: Marco Bosco, Luca Stucchi, Rita Gianni, Antonia Trevisan
  • Patent number: 8524889
    Abstract: An object of the present invention is to provide a novel starchy substance having a retrogradation-resistance, a process for producing the starchy substance efficiently from a material starch by enzymatic reaction, and uses thereof. The present invention attains the above object by providing branched starch having 6-?-maltosyl- and/or 6-?-maltotetraosyl-structure(s) with a marked retrogradation-resistance, a process for producing the branched starch without lowering the molecular weight of material starch, and uses thereof.
    Type: Grant
    Filed: April 10, 2012
    Date of Patent: September 3, 2013
    Assignee: Hayashibara Co., Ltd.
    Inventors: Tomoyuki Nishimoto, Katsuhiko Hino, Takanori Okura, Hiroto Chaen, Shigeharu Fukuda, Toshio Miyake
  • Patent number: 8524887
    Abstract: This invention relates a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate and processes to produce the cellulose solution. Another aspect of this invention relates to shaped articles prepared from a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate. Another embodiment of this invention relates to compositions comprising derivatives of cellulose prepared from a cellulose solution comprising at least one tetraalkylammonium alkylphosphate. Another embodiment of this invention relates to compositions comprising regioselectively substituted cellulose esters prepared from a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate. In another embodiment of the invention, the cellulose esters of the present invention are used as protective and compensation films for liquid crystalline displays.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: September 3, 2013
    Assignee: Eastman Chemical Company
    Inventors: Charles Michael Buchanan, Norma Lindsey Buchanan, Elizabeth Guzman-Morales
  • Patent number: 8524768
    Abstract: Antioxidant compositions for the treatment and prophylaxis of illnesses associated with oxidative stress and lack of oxygen in the human body, comprising a complex of a metal selected from the group consisting of iron, copper, zinc and manganese with rutin and ascorbic acid and/or dihydroascorbic acid. Methods for synthesizing the antioxidant compositions and granulates, tablets and capsules containing antioxidant compositions are also provided.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: September 3, 2013
    Inventor: Isaak Grigorievich Gitlin
  • Patent number: 8481695
    Abstract: Kits and compositions for producing an alginate gel are disclosed. The kits and compositions comprise soluble alginate and insoluble alginate/gelling ion particles. Methods for dispensing a self-gelling alginate dispersion are disclosed. The methods comprise forming a dispersion of insoluble alginate/gelling ion particles in a solution containing soluble alginate, and dispensing the dispersion whereby the dispersion forms an alginate gel matrix. The methods may include dispensing the dispersion into the body of an individual. An alginate gel having a thickness of greater than 5 mm and a homogenous alginate matrix network and homogenous alginate gels free of one or more of: sulfates citrates, phosphates, lactatates, EDTA or lipids are disclosed. Implantable devices comprising a homogenous alginate gel coating are disclosed. Methods of improving the viability of pancreatic islets, or other cellular aggregates or tissue, following isolation and during storage and transport are disclosed.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: July 9, 2013
    Assignee: FMC Biopolymer AS
    Inventors: Jan Egil Melvik, Michael Dornish, Edvar Onsoyen, Astrid B. Berge, Terje Svendsen