Abstract: This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information.

Abstract: A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.

Abstract: The invention lies in the domain of medical technology and relates to a diagnosis and monitoring device for the rapid diagnosis and monitoring of vital parameters of the human or animal body, in particular of the heart and/or lungs, said device being compact, without cables and/or tubes and easy to use for the user. Devices such as a bell (1) comprising a membrane (2) and/or measuring electrodes (4, 5) for receiving and forwarding acoustic and/or electric signals of the body are arranged in a housing with a cross-section that is approximately the size of the palm of a hand and a height of approximately half a hand-width, on the side of a housing that is to be placed on the body.

Abstract: The present invention is directed to a novel shape-transferring cannula system, which provides access to tortuous and unsupported paths. The shape-transferring cannula system and method enables exploration of hollow body structures, and creates a custom-contoured access port for insertion and removal of, for example, diagnostic, surgical, or interventional instruments to and from a site within the body to which the physician does not have line-of-sight access.

Abstract: A medical thermometer with a miniature sensor that touches the patient's skin by a spring-loaded probe. The device computes a deep body temperature by using data of probe housing temperature and accounting for multiple responses of skin contact temperature sensor before and after touching the skin. A motion detector is employed to turn power on automatically.

Abstract: An integrated lancing test strip includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing a lancet to maintain the sterility of the lancet and prevent cross-contamination between the test strip and the lancet. The sterility sheet allows the lancet to be sterilized separately from the test strip. In one form, a firing mechanism has a blade that punctures and slits the sterility sheet during the firing cycle to reduce the chance of cross contamination between the lancet and the test strip prior to use. This allows an operator to load and subsequently remove an unused integrated lancing test strip without compromising the sterility of the lancet. The lancet includes an engagement opening in which the blade of the firing mechanism engages the lancet. The engagement opening is configured to reduce the chance of the blade becoming dull.

Abstract: A body fluid sampling device includes a firing mechanism that is configured to be automatically cocked and fired. In one form, the device includes an electric motor that is operable to cock the firing mechanism and fire an integrated lancet/sampling device to form an incision in skin. Subsequent to formation of the incision, the integrated lancet device is temporarily removed from the skin to promote bleeding from the incision. After a specified period of time, the integrated lancet device is then repositioned against the skin in order to collect a fluid sample.

Abstract: A media-dispensing apparatus for testing body fluids and a method of using the same are disclosed. The apparatus includes a housing having a lower portion and an upper portion, and an elongated tubular member having a distal opening adjacent a distal end thereof. The elongated tubular member includes a first lumen within the elongated tubular member extending from the lower portion of the housing to the distal opening and includes a second lumen within the elongated tubular member extending from the upper portion of the housing to the distal opening. A media strip is dispensable from the lower portion of the housing, through the first lumen, out the distal opening of the elongated tubular member, through the second lumen and into the upper portion of the housing.

Abstract: A surgical access system including a tissue distraction assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site. Some embodiments of the surgical access system may be particularly suited for establishing an operative corridor to a surgical target site in the spine. Such an operative corridor may be established through the retroperitoneal space and the psoas muscle during a direct lateral, retroperitoneal approach to the spine.

Abstract: An apparatus (10) and method for excising tissue (208) and closing a wound (156) that results from excision of the tissue (208) is provided. The apparatus (10) includes structure (14) defining an aperture (34) into which tissue (208) to be excised is exposed and a cutting member (96). The apparatus (10) also includes an adhesive bandage (140) for closing the wound (156). The adhesive bandage (140) is secured relative to a lower surface (20) of the structure (14) in a location for contacting skin (154) adjacent to the tissue (208) to be excised. The apparatus (10) further includes a device (150) that is actuatable for closing the wound (156) with the adhesive bandage (140) and actuators (108 and 182) for moving the cutting member (96) relative to the structure (14) for excising the tissue (208) exposed in the aperture (34) and for actuating the device (150).

Abstract: Skin test device has a film backing. The film backing is made of silicone, and is marked off into divisions by grooves. The divisions each have a different sample containing a suspected allergen. The film backing has a see-through feature and the condition of the skin can visually be checked when the film backing is staying on the skin. The divisions are easily separable from each other. When certain samples cause significant allergic reactions, the divisions corresponding to those samples can be removed immediately.

Abstract: A method for scaling the impedance measured during the course of an electrophysiology study accounts for impedance drifts. By scaling the impedance there is greater assurance that previously recorded positional information can be used to accurately relocate an electrode at a prior visited position. The scale factor may be based upon a mean value across several sensing electrodes. Alternatively, the scale factor may be calculated specifically with respect to an orientation of a dipole pair of driven electrodes.

Abstract: A multiple use analyte sensing assembly that includes a long, thin conductor. A plurality of sensing sites are spaced along the conductor and each sensing site includes a membrane system adapted to create a current when placed into contact with body fluid containing the analyte. The assembly also includes a housing, having an aperture, an uptake spool and a payout spool, the conductor being wrapped about the payout spool before the sensing assembly is used. A sensor positioning actuator turns the uptake spool to move each sensing site, in sequence, to the housing aperture and then to the uptake spool. The assembly also includes a skin broaching assembly, having a multiplicity of lancets and a lancet positioning actuator adapted to move each lancet to the aperture. In addition, a lancet use actuator is adapted to move each lancet at least partially through the aperture and then back again.

Abstract: A surgical instrument including an elongate member having opposite ends, and a clevis attached to one end of the opposite ends. The clevis has a pair of spaced arms. The instrument includes a pin extending between the spaced arms of the clevis, and a pair of end effectors. Each of the end effectors has a pivot hole adapted for receiving the pin extending between the spaced arms of the clevis for pivotal movement relative to the clevis and a control arm for pivoting the respective end effector about the pin. The control arm includes an actuation hole and a tang adjacent the actuation hole. The instrument includes an actuator wire extending longitudinally to a laterally extending end received within the actuation hole. A portion of the longitudinally extending wire adjacent the laterally extending end and actuation hole is engaged by the tang to maintain the wire in the actuation hole.

Abstract: An imaging endoscope comprising a shaft having a proximal end adapted to be secured to a handle, and a distal end having a biopsy forceps disposed therein. The biopsy forceps includes one or more end-effector elements that are actuated with a control cable that may be connected to the handle. The endoscope shaft includes a biopsy sample lumen that is configured to receive a biopsy sample obtained from the forceps assembly. A sample collection apparatus is attached to the handle to capture multiple biopsy samples. In some embodiments, the endoscope is a single-use endoscope.

Abstract: A temperature sensing device accurately determines the core temperature of a warm blooded animal or human based on at least one measurement of the temperature of the skin of the warm blooded animal or human. The device includes a housing, and a first contact type temperature sensing element coupled to the housing. The first contact type temperature sensing element includes a first temperature sensor that is operative to measure the temperature of the skin when the first contact type temperature sensing element is in contact with the skin. The first temperature sensor produces at least a first signal representative of the measured skin temperature. An electronic circuit uses the first signal to determine the core temperature of the warm blooded animal or human. An electronic communication device, such as a display, is coupled to the electronic circuit for communicating the core temperature to a user.

Abstract: A device, method, and system are provided for immobilizing and stabilizing a breast in preparation for tumor ablation or biopsy while the patient is lying supine. The breast is lifted away from the chest wall of the patient, so that the tissue abnormality to be treated is also lifted away from the chest wall. This reduces the possibility of damage to the neighboring costochondral wall and the surrounding healthy tissue. The device includes a medical device holder that can be used to accurately aim a medical probe, and hold it in place during treating.

Abstract: The invention is directed to devices and methods for separating and collecting a tissue specimen from a patient's target site. The device includes a probe member with a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having an tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member.

Abstract: An integrated lancing test strip includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing a lancet to maintain the sterility of the lancet and prevent cross-contamination between the test strip and the lancet. The sterility sheet allows the lancet to be sterilized separately from the test strip. The sterility sheet gives the integrated strip a low profile, which is attractive for packaging multiple integrated strips in cassettes, drums, magazines or the like. In one form, the integrated strip is loaded in a meter that includes an adjustment mechanism that adjusts the position of the test strip relative to the skin being sampled. This allows the user to adjust the position of the test strip so as to not apply excessive pressure against skin, which could hamper bleeding from the incision in the skin.

Abstract: In a body fat measuring apparatus, a constant electric-current is flowed between hand electric-current electrodes and leg electric-current electrodes. From two detected voltages generated between an annular-shaped voltage electrode placed on an abdominal portion and two voltage electrodes placed at the both sides of a lumbar portion, two abdominal impedances are determined. Two electric-current electrodes and two voltage electrodes are placed such that they are spaced apart by a small interval from one another at an umbilicus portion. A constant electric current is flowed between the two electric-current electrodes and the impedance in the vicinity of the subcutaneous of the abdominal portion is determined from the detected voltage generated between the two voltage electrodes. From the two abdominal impedances, the impedance in the vicinity of the subcutaneous of the abdominal portion, and the input physique information, a viscera impedance is calculated.