Abstract: The present disclosure discloses a flat panel detector, a driving method thereof and a detection device. The flat panel detector includes: at least one stage of first demultiplexer, wherein signal output terminals of a first stage of first demultiplexer are connected with the scanning signal lines in one-to-one correspondence, signal output terminals of other stage of first demultiplexer serves as signal input terminals of the previous stage of first demultiplexer, the first demultiplexers are configured to provide signals of the signal input terminals to all the signal output terminals in time division, the signal input terminals and the signal output terminals included in the different stages of first demultiplexers differ from one another, and the quantity of the signal input terminals and the quantity of the signal output terminals are reduced stage by stage from the first stage of first demultiplexer to the last stage of first demultiplexer.

Abstract: The present invention relates to the dose adjustment device mountable to diagnostic radiation equipment and the dose adjustment system which allows radiation exposure in each portion of in the irradiation area to be prevented, and are configured as modules that are attachable to diagnostic radiation equipment, thus having the effect of allowing a radiation shielding function to be easily added to existing equipment without changing the structure thereof.

Abstract: An estimation device includes at least one processor, in which the processor functions as a learned neural network that derives a result of estimation of at least one emphasis image in which a specific composition of a subject including a plurality of compositions is emphasized from a simple two-dimensional image acquired by simply imaging the subject. The learned neural network is learned by using, as teacher data, a composite two-dimensional image representing the subject, which is derived by combining a three-dimensional CT image of the subject, and an emphasis image for learning in which the specific composition of the subject is emphasized, which is derived from the CT image.

Abstract: For decision support in a medical therapy, machine learning provides a machine-learned generator for generating a prediction of outcome for therapy personalized to a patient. Deep learning may result in features more predictive of outcome than handcrafted features. More comprehensive learning may be provided by using multi-task learning where one of the tasks (e.g., segmentation, non-image data, and/or feature extraction) is unsupervised and/or draws on a greater number of training samples than available for outcome prediction alone.

Abstract: Disclosed herein are MEMS devices and systems and methods of manufacturing or operating the MEMS devices and systems. In some embodiments, the MEMS devices and systems are used in imaging applications.

Abstract: There is provided a method for determining presence of a person comprising a) receiving IR sensor data (50) during a first time period from a thermopile and using the IR sensor data to determine an IR background signal baseline (51) for the time period, and determining a variability of the IR sensor data (50), b) using the IR background signal baseline (51) and the variability of the IR background signal level to determine a threshold (52) with a value higher than the background signal baseline (51), and in such a way so that greater variability in the IR background signal (50) results in a higher threshold (52), then c) receiving further IR sensor data (50) during a second time period, which is after the first time period, and using the further IR sensor data (50), and the threshold (52) determined in step b) to determine that a person is present when the further IR sensor data (50) comprises a value that is higher than the threshold.

Abstract: A radioactivity measurement device for measuring an activity level of a radioisotope source is provided. The radioactivity measurement device comprises a housing and a self-powered detector. The housing comprises an outer shell and an inner shell, wherein the inner shell is adapted to house an insertable radioisotope source, and wherein the outer shell and the inner shell are configured to form a hollow annular region. The self-powered detector, positioned within the hollow annular region of the housing, comprises at least one tubular emitter configured to provide a source of electron emission proportional to a radioisotope activity level of the insertable radioisotope source and at least one tubular collector configured to sink the electron emission. A radioactivity level measurement system comprising at least one radioactivity measurement device, a shipping cask incorporating the radioactivity level measurement system and a method for shipping the shipping cask are also provided.

Abstract: An apparatus for detecting X-ray, comprising an X-ray absorption layer comprising an electrode, an electronics layer and a wall sealing a space among electrical connections between the X-ray absorption layer and the electronics layer. The electronics layer comprises: a first and second voltage comparators configured to compare a voltage of an electrode to a first and second thresholds respectively; a counter configured to register a number of X-ray photons absorbed by the X-ray absorption layer; and a controller configured to: start a time delay from a time at which an absolute value of the voltage equals or exceeds an absolute value of the first threshold; activate the second voltage comparator during the time delay; cause the number registered by the counter to increase by one, if, during the time delay, an absolute value of the voltage equals or exceeds an absolute value of the second threshold.

Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.

Abstract: The invention provides a detection system for ionizing radiation, a method of manufacturing a detection system for ionizing radiation, a method of detecting ionizing radiation, a detection chamber for detecting ionizing radiation by liquid scintillation counting, and a method of detecting ionizing radiation by liquid scintillation counting. The detection system for ionizing radiation comprises a detector with a detection surface. The detector is configured to detect ionizing radiation that is incident on the detection surface. An adsorption layer is provided on said detection surface, the adsorption layer being configured to bind target particles, wherein the target particles are radioactive atoms or molecules.

Abstract: Image information regarding a particular patient is provided, which image information includes, at least in part, a tumor to be irradiated. These teachings can also include providing non-image clinical information that corresponds to the particular patient. A control circuit accesses the foregoing image information and non-image clinical information and automatically generates a clinical target volume that is larger than the tumor as a function of both the image information and the non-image clinical information. The control circuit can then generate a corresponding radiation treatment plan based upon that clinical target volume, which plan can be utilized to irradiate the clinical target volume.

Abstract: Techniques are presented for optimizing a treatment plan for charged particle therapy. The method includes obtaining medical image data voxels inside a subject in a reference frame of a radiation source that emits a beam of charged particles at multiple tracks with a controlled emitted energy at each track. Hydrogen density (HD) is determined based on the medical image data. Stopping power ratio (SPR) along a first beam having a first track and first emitted energy is calculated based on HD. A range to a Bragg peak is calculated along the first beam based on the SPR and the first emitted energy. The first beam track or the first emitted energy, or both, is modified based at least in part on the beam range to determine a second track and second emitted energy. Output data that indicates the second track and second emitted energy are sent.

Abstract: An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.

Abstract: A system for imaging particles in a fluid includes a substrate holder for holding a substrate comprising a channel or reservoir for containing the fluid in the substrate, a radiation source for providing irradiation in the substrate and a radiation detection unit for detecting particles in the fluid in the substrate. At least one of the radiation source and the radiation detection unit) are configured to obtain detection in one or more distinct detection sheets in the substrate. The system further comprises an actuator configured for imparting an oscillating mechanical movement of the substrate holder regarding the radiation detection unit and the radiation source, the oscillating mechanical movement being a movement comprising a movement component in a direction perpendicular to the plane wherein the one or more detection sheets are extending.

Abstract: The treatment couch includes a couch panel, a main supporting structure, an auxiliary supporting structure and a supporting beam. Both ends of the supporting beam are respectively connected to the main supporting structure and the auxiliary supporting structure.

Abstract: A method comprises inputting a treatment planning image of a target subject into a machine learning system. The method further comprises determining, by the machine learning system, a first target-subject-specific model of the treatment planning image. The method further comprises applying, by a processing device, the first target-subject-specific model to the treatment planning image to generate a transformed treatment planning image corresponding to a first position of a plurality of positions of the target subject. The method further comprises comparing the transformed treatment planning image to a reference image. The method further comprises, based on the comparing, modifying one or more parameters of the first target-subject-specific model to generate a second target-subject-specific model corresponding to a second position of the plurality of positions.

Abstract: A method for generating a response function of a scintillator to incident gamma rays of energy within a range of energies of interest, the method including: obtaining the responses {Si} of the scintillator to a plurality of known radionuclides i (i=1, . . . N), each radionuclide i emitting gamma rays with known energetic properties (Eij, Yij), decomposing, for each radionuclide i, response Si into primary responses of the scintillator Sij=ƒ(?ij, Yij, Xij), each primary response corresponding to the response of the scintillator to a received gamma ray of a known energy Eij for this radionuclide i, deriving from the primary responses {Sij} the response function ƒ(?, X) of the scintillator to an incident gamma ray of any energy E within the range of energies of interest.

Abstract: A device for performing a radiological examination on a patient having a part of the body examined includes a housing with an openable containment portion and an examination portion. The containment portion and the examination portion together substantially enclose the patient. The examination portion is substantially transparent to X-rays and is configured to contain the part of the body to be examined.

Abstract: A method of imaging comprises disposing a population of first targeting ultrasound-switchable fluorophores and a population of second non-targeting ultrasound-switchable fluorophores in an environment; detecting a first photoluminescence signal emitted by the population of first targeting fluorophores, and a second photoluminescence signal emitted by the population of second non-targeting fluorophores; determining a photoluminescence property of the population of second non-targeting fluorophores from the second photoluminescence signal; and using the determined photoluminescence property of the population of second non-targeting fluorophores to deconvolute the first photoluminescence signal into the population of first targeting fluorophores bound and unbound to a first target binding element in the environment.

Abstract: For determining whether oil waste at a field testing site is exempt from selected naturally occurring radioactive material (NORM) waste regulations, a measurement apparatus including a detection module that determine radioactivity counts per minute for an oil waste sample is utilized. The measurement apparatus includes an analysis module that uses a first nonlinear transfer function to determine a mass for the oil waste based on a volume of solids determined via BS&W testing. The analysis module uses a second nonlinear transfer function to determine a maximum radioactivity level for the sample which is then normalized to picoCuries/g. The normalized maximum radioactivity level per gram is compared to a NORM exemption level for a selected region and communicated to entities at the field-testing site and optionally to other entities. A system and a method perform the functions of the measurement apparatus.