Abstract: An electrochemical method for measuring the activity of biomarkers using microelectrode arrays functionalized with peptide consensus sequences and redox reporter moieties. Contact of the arrays with a biological sample containing one or more target biomarkers results in cleavage of the peptides and changes the electric current across the array in a quantifiable manner indicating not just the presence of the target biomarker in the sample, but its activity.
Type:
Grant
Filed:
April 26, 2022
Date of Patent:
May 5, 2026
Assignees:
Kansas State University Research Foundation, United States of America as Represented by the Administer of NASA
Inventors:
Jun Li, Duy H. Hua, Morgan James Anderson, Jessica Erin Koehne, Meyya Meyyappan