Abstract: Disclosed is a method for preparing an aqueous phytosphingosine solution containing as much as 5-10 weight % of phytosphingosine without using any solvents other than water. A high content of phytosphingosine is dissolved in water and lactic acid with the help of a willow bark extract. In addition to being clear, the aqueous phytosphingosine solution is able to recover damaged skin with activity against bacteria and inflammation. Also, when being applied for cosmetics, the aqueous phytosphingosine solution allows them to contain as much as 1-2 weight % of phytosphingosine by virtue of its high content of phytosphingosine. Further, the phytosphingosine solution is greatly improved in compatibility with cosmetic components so that it can be readily applied for aqueous cosmetics such as skin lotions, essence lotions, aqueous pack products, body essence compositions, etc., for which phytosphingosine has not yet been applied, thus far.
Type:
Grant
Filed:
October 18, 2000
Date of Patent:
June 11, 2002
Assignee:
Doosan Corporation
Inventors:
Chang Seo Park, Jin Wook Kim, Jee Hean Jeong
Abstract: The present invention relates to an Extract of Echinops spinosus L (Asteraceae) and organic solvent soluble fractions of the extract that may be used in the treatment of cancer.
Type:
Grant
Filed:
September 28, 2000
Date of Patent:
May 28, 2002
Assignee:
McGill University
Inventors:
Moulay A. Alaoui-Jamali, Gerald Batist, Lolita Zamir
Abstract: The present invention is related a high viscosity xanthan and processes for producing said high viscosity xanthan. In particular, the invention relates to a process for increasing the viscosity of xanthan comprising the steps of: (i) diluting xanthan in a fermentation broth with more than 30 percent by volume of a diluent to said fermentation broth volume; and (ii) pasteurizing said diluted xanthan fermentation broth. A particularly preferred pasteurization process is to utilize steam from a direct steam injection system. Xanthans with increased viscosities have improved product functionality for a number of different commercial applications are produced using the processes of the present invention.
Type:
Grant
Filed:
September 19, 2000
Date of Patent:
May 21, 2002
Assignee:
CP Kelco U.S., Inc.
Inventors:
Todd A. Talashek, William Scott Bousman
Abstract: Novel microorganisms, which can be obtained by the following selection method:
(a) microorganisms which grow using N-acetylglucosamine as the sole carbon source are cultivated in a customary manner,
(b) from the resulting culture, these microorganisms are then selected which are stable and have the property to metabolize N-acetylglucosamine rapidly in the presence of N-Acetylmannosamine.
Furthermore, a novel process for preparing NAM starting from a mixture of NAM and NAG.
Abstract: A microorganism having indolmycin-producing ability and tryptophan analogue resistance is provided, and indolmycin or its salt can be produced efficiently by cultivating such microorganism in a medium to produce and accumulate indolmycin or its salt in the culture broth followed by recovering a product.
Abstract: The present invention relates to a novel bacterial consortium EBC1000 (KCTC 0652 BP) and a method for remedying biologically a chlorine compound and recalcitrant toxic chemicals contained in industrial wastewater, waste materials and soils using the bacterial consortium EBC1000. The novel bacterial consortium EBC1000(KCTC 0652 BP) is composed of aerobic bacterium easy to culture and useful for decomposing a chlorine compound and waste acidic or alkaline recalcitrant toxic chemicals of high concentration contained in the industrial waste materials, such as IPA, MC, DMA, AN, SHS, BD, Tamol-SN, EDTA, FES, TDDM, PMH, DEHA, MeOH, NaOH and CH3CN, thus preventing and recovering environmental pollutions.
Abstract: The present invention pertains to a method of identifying and selecting desiccation tolerant strains of bacteria and a method of producing a desiccated formulation of the identified strains.
Abstract: A process has been developed for production of a food flavoring compound maltol which comprises (a) extracting the dried and pulverized leaves of the plants belonging to the genus Abies with an alcohol at 20-40° C. and concentrating the solvent to obtain an alcoholic extract, (b) adsorbing the alcoholic extract with an adsorbent and drying the adsorbed material at a temperature ranging between 20-50° C., (d) partitioning of the adsorbed material between selected solvents consisting of aliphatic hydrocarbon and chlorinated solvent successively, (d) concentrating the chlorinated solvent to a residue and crystallizing it from a suitable organic solvent or mixtures of such solvents to get pure maltol.
Type:
Grant
Filed:
February 26, 2001
Date of Patent:
May 7, 2002
Assignee:
Council of Scientific & Industrial Research
Abstract: The present invention provides a composition which is useful for promoting hair growth and methods for using the same. The hair growth promoter composition comprises a compound of the formula:
wherein X, R1, R2, Z1, and Z2 are those described herein. Preferably, the compound comprises at least two saccharide moieties.
Abstract: A method for making and identifying processed botanical materials as being of a pharmaceutical grade for use in clinical settings and patient treatment. The method utilizes fingerprints of the processed botanical material with respect to bioactivity and/or composition to establish whether the material meets previously established pharmaceutical grade requirements. The method is applicable to processed botanical materials, such as plant extracts, powders and the like which are used in medicinal applications.
Type:
Grant
Filed:
April 15, 1996
Date of Patent:
April 30, 2002
Assignees:
PharmaPrint, Inc., University of Southern California
Abstract: The present invention relates to antigenic preparations comprising polysaccharides and/or glycopeptides preparable from keratinophilic fungi as well as yeasts, processes for the preparation of these antigenic preparations, their use as pharmaceutical substances as well as their use as vaccines, including but not limited to, the prophylaxis and treatment of allergy, as well as for modulating the immune response.
Type:
Grant
Filed:
May 15, 1998
Date of Patent:
April 30, 2002
Assignee:
Boehringer Indgelheim Vetmedica GmbH
Inventors:
Dieter Farnow, Joachim Karle, Igor D. Poliakov, Ludmilla G. Ivanova
Abstract: The populating method for populating a substrate with living cells provides a population with at least one populating phase and at least one perfusion phase. During the populating phase the substrate can be held in contact with the cell suspension by continuous rotation in various spatial arrangements. The populating device of the invention (10) comprises a rollable container (10a) and a removable insert in it with a means (12) for inserting the substrate being populated, such as a plastic or collagen matrix. The insert is designed so that in interaction with the inserted substrate, two liquid-tight chambers are formed within the container on opposite sides of the inserted substrate, so as to allow separate populating of both sides of the substrate. The container have liquid inlets and outlets (16) and may also have gas inlets and outlets. The rollable populating reactor (10) is inserted into a roller cabinet for certain phases of the populating.
Abstract: The present invention relates to a method of transferring at least two saccharide units with a polyglycosyltransferase, a polyglycosyltransferase and a gene encoding such a polyglycosyltransferase.
Type:
Grant
Filed:
June 24, 1999
Date of Patent:
April 30, 2002
Assignee:
Neose Technologies, Inc.
Inventors:
Karl F. Johnson, Stephen Roth, Stephanie L. Buczala
Abstract: Polycarboxylic acids are purified by contacting a crude polycarboxylic acid with a solvent to produce a substantially pure polycarboxylic acid. The solvent is chosen so that the impurities are soluble in the solvent and the polycarboxylic acid is insoluble in the solvent.
Abstract: The invention relates to matrix-forming amylose products for programmed release systems and a process for the preparation thereof. These amylose products have a dextrose equivalent (DE) of 5 to 10, a content of long-chain amylose of 20 to 40 wt. % on dry substance, a content of short-chain amylose of 40 to 80 wt. % on dry substance and a specific surface area of 0.4 to less than 1.0 m2/g.
Type:
Grant
Filed:
September 13, 1999
Date of Patent:
April 23, 2002
Assignee:
Cooperatieve Verkoop-en Productievereniging Van Aardappelmeel
en Derivaten Avebe B.A.
Inventors:
Jacob Bergsma, Gerrit Henk Peter Te Wierik, Jan Aten, Anna Wilhelmina Arends-scholte
Abstract: The process includes a first stage to eliminate polyphenols from the starting vegetable isolates, followed by a double hydrolysis treatment, firstly with non-specific endoproteases and then, with specific endoproteases and exoproteases. The hydrolyzed peptones obtained in this way are applicable to the agroalimentary and medico-pharmaceutical industries, especially in the sectors of human, animal and clinical nutrition.
Type:
Grant
Filed:
November 9, 1998
Date of Patent:
April 16, 2002
Assignees:
Consejo Superior de Investigaciones Cientificas, Universidad de Seville
Inventors:
Francisco Millan Rodriguez, Juan Bautista Palomas, Jose Manuel Olias Jimenez
Abstract: A deer repellent formulation and method for warding off a deer from a shrub or plant. The formulation is an admixture of water, Rosemary oil emulsion, mint oil emulsion, a thickener, white distilled vinegar and dry eggs. The formulation can be applied to a support medium such as clay or a length of rope and then associated with the vegetation to be protected. The formulation can also be formed into a viscous composition and used in containers near the vegetation to be protected.
Abstract: A device for performing a biological modification of a fluid, particularly in order to assist or replace the functioning of an organ which normally performs this modification, including a collection of liver micro-organ cultures. The device of the present invention is preferably directly connected to a subject for performing this modification.
Type:
Grant
Filed:
July 15, 1999
Date of Patent:
April 16, 2002
Assignee:
Yissum Research Development Company of the Hebrew University
of Jerusalem
Abstract: The present invention describes new and distinct strains of higher Basidiomycetes mushrooms, and a process for growing them in submerged culture. Specifically, the new strains of species of the genus Pleurotus offer superior yields of mushroom biomass and concentrations of biologically active compounds, for example, cholesterol-lowering compounds, lectins, proteins, essential amino acids, vitamins or polysaccharides. The process includes use of defined media and a simple one-step procedure of separating the lovastatin-containing nutriceuticals from culture broth.
Type:
Grant
Filed:
October 15, 1999
Date of Patent:
April 16, 2002
Assignee:
MedMyco Ltd.
Inventors:
Solomon P. Wasser, Sergey V. Reshetnikov
Abstract: Use of a staphylococcus bacteria or a product thereof for the manufacture of a pharmaceutical preparation for treatment and/or prevention of fibromylagia and chronic fatigue syndrome. Preferably, the preparation also comprises vitamin B12 and/or folacin. A method for treatment of and/or prevention of chronic fatigue syndrome or fibromylagia, characterized in that a staphylococcal preparation is administered in a therapeutically effective amount, preferably in combination with or parallel with vitamin B12 and/or folacin. The preparation is preferably administered repeatedly, first 8-10 times during a period of 4-12 weeks when the dose is increased from a relatively lower dose the first administration to a relatively higher dose the last administration, then approximately once a week for 5-15 weeks, and finally approximately once a month for a period of 1-10 years.