Abstract: Toothpaste containing abrasive particles of milled alpha-alumina trihydrate, alkali metal monofluorophosphate and alkali metal fluoride, the total fluoride corresponding to about 500 to 1000 ppm F, which toothpaste is compatible with an unlined aluminum container and is effective to reduce enamel solubility.

Abstract: A method for the treatment of chronic obstructive airway disease or cardiac disease by administration 3-ethylxantine or a pharmaceutically acceptable salt thereof; a pharmaceutical preparation containing 3-ethylxanthine.

Abstract: Novel treatments are disclosed for increasing circulating coronary blood flow. These treatments are useful for individuals who are expected to otherwise exhibit symptoms of reduced coronary circulation. Such individuals include those having coronary artery disease, angina, particularly unstable angina and Prinzmetal's angina, and coronary vasospasm. In accordance with the disclosed methods, coronary vasodilation is accomplished through the administration of effective amounts of ibuprofen and/or flurbiprofen. At the indicated dosages, thromboxane synthesis is effectively inhibited without inhibiting prostacyclin synthesis. Flurbiprofen administration additionally results in thromboxane antagonism.

Abstract: The invention provides a method of treatment of the human or animal body comprising the application of an aqueous solution containing a compound of formula I ##STR1## [wherein R.sup.1 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms and R.sup.2 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms or a group of formula II ##STR2## in which R.sup.1 is as defined above] to human or animal tissue subjected to surgical treatment whereby the incidence of adhesion formation is eliminated or substantially reduced or whereby existing adhesions are at least substantially detached or unblocked. There is also provided a solution for use in the above method.

Abstract: An oral composition for caries prophylaxis which comprises a highly soluble stannous compound such as stannous fluoride preferably in an amount of 0.03 to 5% by weight of the composition as stannous tin, a difficultly soluble stannous compound such as stannous pyrophosphate preferably in an amount of 0.05 to 10% by weight of the composition as stannous tin, a phytic acid compound such as sodium phytate preferably in an amount of 0.1 to 20% by weight of the composition, and the pH of the composition being preferably acidic. A portion of the difficultly soluble stannous compound may be in a precipitate form. The oral composition which may be used as dentifrices, prophylactic pastes, dental flosses and the like permits n.sup.2+ ions to exert its effect because the storage stability is high enough to maintain the increased concentration of active dissolved stannous ions in the composition for a prolonged period of time and can render the tooth enamel more resistant to acid attack when applied to teeth.

Abstract: A method for treating peripheral orthostatic hypotension which comprises administering DL- or L-threo-3,4-dihydroxyphenylserine or a pharmaceutically acceptable acid addition salt thereof to a subject suffering from the disease. The composition may be administered either orally or parenterally.

Abstract: Blood pressure is increased in a patient having a condition which effects rapid firing of neurons in the sympathetic nervous system and low blood pressure by administering tyrosine to the patient. The tyrosine composition can be administered alone or concomitantly with a drug which increases noradrenergic neurotransmission in the sympathetic nervous system.

Abstract: Improvement in hypertension in man is achieved through the use of sodium bisulfite.

Abstract: An aqueous solution of nitroglycerin comprising at least one substance selected from among sorbitol, mannitol and xylitol in addition to nitroglycerin, and having a high degree of stability for storage.

Abstract: The application discloses a pharmaceutical composition for treating hypertension containing (A) L-.alpha.-methyl-3,4-dihydroxyphenylalanine and (B) salicylamide, phenylglyoxal or L-ascorbic acid.

Abstract: Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating pulmonary fibrosis.

Abstract: A glucose solution for drip phleboclysis characterized by the inclusion therein of L-carnitine is disclosed. The presence of L-carnitine improves the muscle tissue absorption and utilization of glucose, thus preventing excessive insulin secretion. This permits the utilization of 10% glucose solutions, and also in excess of 10%, without any risk for the patient even in the case of long-term treatment.

Abstract: A preparation and method for the treatment of burn victims. The preparation comprises an aqueous mixture of a perborate stabilized aqueous solution of chlorine oxides and glycerine. The preparation is applied to the burn area as a wet compress and the area exposed to ambient air between such applications.

Abstract: Benzodiazepine derivatives which have tranquillizing activity, especially 1,4-benzodiazepine derivatives, can lower the serum prolactin concentration. They can reduce, dosage-dependently, the increase in the serum prolactin concentration induced by the administration of neuroleptics, which can lead to undesirable side-effects, when about 0.01 to 100 parts by weight of benzodiazepine derivatives are administered per part by weight of neuroleptic, it being immaterial whether the benzodiazepine derivative is administered before or after the neuroleptic or simultaneously therewith. The simultaneous administration of the active substances can be carried out as an ad hoc combination or in the form of a pharmaceutical combination.

Abstract: A cationic surfactant of the formula ##STR1## wherein R' represents a hydrocarbon radical containing up to 30 carbon atoms and derived from lanolin, natural waxes or resin acids, n is a number between 0.5 and 10, and R.sub.1 and R.sub.2 each independently represent lower alkyl or lower hydroxyalkyl, or together form a heterocycle such as morpholinyl or piperidinyl, is used to prepare cosmetic compositions for application to the skin or hair. Preferably, R' in the surfactant is derived from the alcohols of lanolin and hydrogenated lanolin.

Abstract: Clonidine and lofexidine and the pharmaceutically acceptable salts thereof, which are, inter alia, known antihypertensives, also possess very potent antidiarrheal activity which is non-narcotic and more potent than that of conventional antidiarrheal drugs, such as diphenoxylate.

Abstract: Water-in-oil type emulsions are disclosed wherein the water phase comprises a water-soluble alcohol and the oil phase comprises a volatile component and a soluble personal-care component.The emulsions further comprise certain polydiorganosiloxane-polyoxyalkylene copolymers and, optionally, a silicon-free organic surfactant having an HLB value of from 2 to 10.A preferred composition is a personal-care emulsion composition wherein the volatile, oil-phase component is a methylsiloxane fluid.

Abstract: An anhydrous pseudoplastic and thixotropic oleaginous vehicle is prepared by mixing at least one solid emulsifying agent having an HLB number of 12 or less with an oleaginous material and then cooling the mixture over a temperature range of at least about 15.degree. C., said range encompassing the pour point of said agent.

Abstract: Benzylidene aminoguanidene derivatives, known as effective anti-coccidial agents, are useful as potent anti-giardiasis and anti-trichomoniasis agents.

Abstract: Compositions containing controlled amounts of d-fenfluramine are administered to block the intermittent carbohydrate cravings without necessarily suppressing other food intakes.