Patents Examined by Frederick E. Wadell
  • Antioxidant composition in vivo comprising enol form .delta.-lactone of diketogulonic acid
    Patent number: 5162366
    Abstract: Enol form .delta.-lactone of diketogulonic acid (2,3,6-trihydroxy-4-oxo-2-hexen-5-olide; R-345), which is the enediol type oxidation product of ascorbic acid, and/or its sodium salt, potassium salt or calcium salt has activities of markedly reducing the toxicity of Adriamycin, reducing radiation injury, reducing liver damage induced by an organic halogen compound, and further accelerating recovery from a high blood sugar level in Alloxan-induced diabetes, using vitanim E in combination.
    Type: Grant
    Filed: January 24, 1991
    Date of Patent: November 10, 1992
    Assignee: Nissan Chemical Industries, Ltd.
    Inventor: Eiji Kimoto