Abstract: A system and method for controllably applying the fluids to a body surface or cavity is disclosed. These fluids can include tissue adhesives, hemostats, sealants, anti-adhesives, or any other fluid capable of being applied to a body surface or cavity. In one embodiment, the system and method is used to apply components of a tissue adhesive with the aid of pressurized gas. This system comprises a tube having a proximal end and a distal end, at least one component lumen and a gas lumen which open at the distal end of the tube, a component source connected to the component lumen, a source of pressurized gas connected to the gas lumen, a sensor capable of delivering a sensor signal, a switch connected to the source of pressurized gas, and a control system programmed to switch off the pressurized gas supply when the sensor signal corresponds to a predetermined limit value.