Abstract: An isolated preparation of a new species of bacteria, Thermococcus AV4, is disclosed. Also described is a substantially pure preparation of a protease and a substantially pure preparation of a lipase encoded by Thermococcus AV4.
Abstract: Processes for preparing polypeptides such as ricin A such that soluble polypeptide may be obtained. The pH may be adjusted during the process or the temperature decreased during the terminal portion of the cultivation, and yeast extract may be added to the growth medium during the cultivation. In the case of ricin A the pH is generally adjusted by lowering the pH from a first value such as 6.7 to a second value such as a value between about 5.5 and 6.7.
Type:
Grant
Filed:
March 28, 1994
Date of Patent:
August 20, 1996
Assignee:
Imperial Chemical Industries PLC
Inventors:
Bhuphendra V. Kara, Robert C. Hockney, John E. Fitton
Abstract: A human rotavirus gene encoding the major outer capsid glycoprotein (VP7) of the human rotavirus serotype 4 or a portion or sub-unit thereof. Expression vectors containing such a gene and expressing all or part of VP7 protein of human rotavirus serotype 4. Polyeptides corresponding to all or part of the VP7 protein of human rotavirus serotype 4 and vaccines containing such polypeptides.
Type:
Grant
Filed:
June 16, 1992
Date of Patent:
July 26, 1994
Assignee:
The University of Melbourne
Inventors:
Michael L. Dyall-Smith, Chris Hum, Ian H. Holmes, Michael A. Johnson, Peter R. Reeves