Patents Examined by G. Thomas
  • Process for the preparation of cis-vincamine
    Patent number: 3950345
    Abstract: A process is provided for the preparation of cis-vincamine by oxidising trans-vincamine with tertiary butyl hypochlorite to obtain dehydrovincamine chloride, reducing the dehydrovincamine chloride with a metal in an aqeous acidic medium and neutralising the product, and separating cis-vincamine from the resulting mixture of cis- and trans-vincamines. Cis-vincamine is useful for the treatment of circulatory disorders.
    Type: Grant
    Filed: February 21, 1975
    Date of Patent: April 13, 1976
    Assignee: Synthelabo
    Inventors: Henry Najer, Yves Robert Alain Pascal, Jean Pierre Gaston Lefevre