Patents Examined by Gail Poulos
  • Cell culture medium with antioxidant
    Patent number: 4927762
    Abstract: Cells grown in chemically defined (serum free) media are protected against endogenous oxidizing agents by a nontoxic antioxidant with free thiol groups, at cell densities less than about 10.sup.5 cells/ml, especially DL-penicillamine, N-acetylcysteine, mercaptoproprionic acid, 2-mercaptoethanesulfonic acid, and thiolactate. These agensts are useful in the maintenance and growth of hybridomas in such media.
    Type: Grant
    Filed: November 30, 1988
    Date of Patent: May 22, 1990
    Assignee: Cell Enterprises, Inc.
    Inventor: Frederick J. Darfler