Patents Examined by Gargi Roy
  • Single-chain polypeptides comprising troponin I and troponin C
    Patent number: 7078486
    Abstract: This invention relates to single-chain polypeptides and their genetic sequences comprising human cardiac troponin I and troponin C. The single-chain polypeptide may be expressed recombinantly, and a linker peptide may be interposed between the troponin sequences. A linker peptide of about 6 to about 30 amino acids is preferred. The single-chain polypeptide has utility as a control or calibrator for troponin assays, for the purification of troponin subunits and as an antigen for the preparation of antibodies.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: July 18, 2006
    Assignee: Spectral Diagnostics, Inc.
    Inventors: Qinwei Shi, Qian-Li Song