Patents Examined by Gary B. Nizkol
  • Method for regulating the expression of MHC antigens and CD40 by inhibitors of histone deacetylation
    Patent number: 6518012
    Abstract: The present invention discloses compositions and methods for enhancing the expression of major histocompatability complex (MHC) and costimulatory antigens on tumor cells. The method comprises exposing the tumor cells to inhibitors of histone deacetylation.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: February 11, 2003
    Assignee: Health Research, Inc.
    Inventor: Thomas B. Tomasi