Abstract: Polynucleotide and oligonucleotide probes are described for the diagnostic investigation of mycoses which are caused by Candida albicans. These gene probes are complementary to parts of the genome of C. albicans and are suitable for identifying C. albicans nucleic acids in any sample material, even that which has been amplified. They do not hybridise with nucleic acids from other fungi, bacteria, animals or plants. Processes are described for the diagnosis of C. albicans in clinical samples as well.
Type:
Grant
Filed:
October 28, 1993
Date of Patent:
February 6, 1996
Assignee:
Bayer Akteingesellschaft
Inventors:
Wolfgang Springer, Manfred Plempel, Antonius Lobberding