Patents Examined by Gedeon M Kidanu
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Patent number: 11971333Abstract: A system, an instrument, a computer-implemented method, and a clinical workflow for mesodissection of biological specimens on tissue slides by incorporating annotations. An image of an annotated reference slide is acquired and transposed onto a plurality of serial samples on the tissue slides along with the corresponding annotations and metadata. The serial samples are milled based on the annotations, and the milled tissue is automatically collected along with a milling buffer solution inside milling tips, and then dispensed in designated collection vials. The instrument automates the filling of aqueous buffer inside the milling tips and the monitoring of the buffer solution and the sequential filling of the milling tips. The workflow provides an integrated interface that performs tissue annotation, alignment, dissection, tracking, and reporting on a single screen. The degree of precision, ease of use and repeatability will improve PCR and NGS test results, ultimately providing timely patient results.Type: GrantFiled: March 24, 2020Date of Patent: April 30, 2024Assignees: Ventana Medical Systems, Inc., Roche Sequencing Solutions, Inc.Inventors: Nils B. Adey, Dale B. Emery, Leonid Fomin, Rene M. Guerrero, Emmanuel Naouri, Robert J. Parry, Peter Romanowich
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Patent number: 11953489Abstract: The present invention comprises a test for evaluating spontaneous hydraulic fracturing fluid imbibition and oil displacement method and apparatus utilizing a composite core with a pressurized Amott cell test.Type: GrantFiled: July 14, 2021Date of Patent: April 9, 2024Assignee: Imperative Chemical Partners Inc.Inventor: Timothy C Svarczkopf
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Patent number: 11946829Abstract: A tire sensor device for monitoring a condition of a tire includes a plurality of sensors including a temperature sensor and an accelerometer. The tire sensing device further includes memory configured to store data received by the plurality of sensors and one or more processors coupled with the memory. The one or more processors are configured to perform one or more initial processing operations on the data received by the plurality of sensors. The tire sensor device further includes an antenna, coupled with the one or more processors, configured to wirelessly communicate with one or more external devices.Type: GrantFiled: August 12, 2019Date of Patent: April 2, 2024Inventors: Sunjay Dodani, Wing-Hong Andrew Ko
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Patent number: 11940427Abstract: A liquid chromatography-mass spectrometry (LC-MS) apparatus including an ionization source coupled to a mass spectrometer and a liquid chromatographic (LC) system coupled to the ionization source. The LC system comprises multiple fluidic streams alternately connectable to the ionization source, thereby assigning a detection time window to each fluidic stream from the multiple fluidic streams when connected to the ionization source. The LC-MS apparatus further comprises a controller configured to carry out steps of monitoring an ionization current of the ionization source for the multiple fluidic streams and identifying differences in flow conditions between the multiple fluidic streams based on the monitored ionization current.Type: GrantFiled: September 20, 2021Date of Patent: March 26, 2024Assignee: Roche Diagnostics Operations, Inc.Inventors: Benjamin Tiemann, Stefan Quint, Florian Schweinberger
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Patent number: 11937984Abstract: The present disclosure relates to a system and method for actively detecting an ingress of a medical probe. In accordance with certain embodiments, a method includes monitoring, with a sensor within a medical probe, an internal environment of the medical probe, detecting, with the sensor, at least one of a temperature, pressure, humidity, or concentration of a gas within the medical probe, determining, with a processor that is in communication with the sensor, whether a seal that hermetically seals the medical probe has failed as a function of at least one of the temperature, pressure, humidity, or concentration of the gas, and outputting, with the processor, a notification that indicates whether the seal has failed.Type: GrantFiled: August 25, 2020Date of Patent: March 26, 2024Assignee: GE Precision Healthcare LLCInventor: Rajeev C. Mandwal
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Patent number: 11927515Abstract: Variable temperature analytical instruments are provided that can include: a mobile component comprising a cold source; a substantially fixed analysis component; and an interface configured to couple the mobile component with the analysis component. Variable temperature analytical instruments are also provided that can include: a mobile analysis component; a substantially fixed component comprising a cold source; and an interface configured to couple the mobile component with the analysis component. Variable temperature analytical instruments are also provided that can include: a cold source in thermal communication with an analysis component; and at least one pressure barrier defining a plurality of discrete masses maintained at different temperatures between the cold source and the analysis component.Type: GrantFiled: February 2, 2022Date of Patent: March 12, 2024Assignee: Montana Instruments CorporationInventors: Josh Doherty, Jamesen Motley, William Baker, Joseph Evers, Ben Linkenhoker, Luke Mauritsen, Ryan Murdick, Anjan Reijnders
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Patent number: 11913923Abstract: A method for evaluating physical properties of a melt-blown plastic resin, and, more specifically, to a novel method for evaluating physical properties are provided. When a particular plastic resin is processed by a melt-blown process, a stretching diameter value after the process of the plastic resin can be accurately derived from a physical property value measured using a specimen of the resin.Type: GrantFiled: March 28, 2023Date of Patent: February 27, 2024Assignee: LG Chem, Ltd.Inventors: Hyunsup Lee, Seok Hwan Kim, Heekwang Park, Ki Soo Lee, Sangjin Jeon, Myunghan Lee
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Patent number: 11898999Abstract: Described is a mixer for a liquid chromatography system. The mixer includes a flow distributor, a mixing disk and a flow collector. The mixer includes an inlet face, an outlet face and a plurality of channels each having an inlet end at the inlet face and an outlet end at the outlet face. The channels have a flow direction anisotropy between the inlet and outlet faces. A compositional solvent stream received at the flow distributor is distributed across the inlet face of the mixing disk and the flow collector collects the distributed solvent composition stream after passing through the mixing disk. The mixing disk may include a dispersive medium having a random porous structure. A retention time distribution of the mixer may depend on the structure of the channels between the inlet and outlet faces of the mixing disk.Type: GrantFiled: June 25, 2021Date of Patent: February 13, 2024Assignee: Waters Technologies CorporationInventor: Fabrice Gritti
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Patent number: 11898997Abstract: A liquid chromatography (LC) system comprises an LC switching valve comprising a sample input port, aspiration pump port, needle seat port, waste port leading to a waste, LC pump port and an LC column port. A sample aspiration needle is fluidically connected to the sample input port via a sample receiving conduit, an aspiration pump is fluidically connected to the aspiration pump port. The LC system includes a needle seat fluidically connected to the needle seat port via a needle seat conduit, an LC column fluidically connected to the LC column port, and an LC pump fluidically connected to the LC pump port, for injecting the sample into the LC column when the sample aspiration needle is seated into the needle seat and when the LC pump port is fluidically connected to the needle seat port and the sample input port is fluidically connected to the LC column port.Type: GrantFiled: August 3, 2021Date of Patent: February 13, 2024Assignee: Roche Diagnostics Operations, Inc.Inventor: Indranil Mitra
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Patent number: 11898998Abstract: A method for injecting a sample into a flow of a liquid chromatography system includes providing a flow of a mobile phase, and injecting a volume of a sample into the flow of the mobile phase such that the concentration of the sample within the mobile phase varies with a triangular profile over the course of the injecting.Type: GrantFiled: February 26, 2021Date of Patent: February 13, 2024Assignee: Waters Technologies CorporationInventors: Michael R. Jackson, Joshua A. Burnett
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Patent number: 11898979Abstract: A gas sensor with improved sensitivity. The gas sensor comprises an active sensor unit, a reference sensor unit and a temperature control circuit. The active sensor unit has an active detector. The reference sensor unit has a reference detector. The temperature control circuit is provided and configured to keep a detector at a predetermined temperature.Type: GrantFiled: September 24, 2020Date of Patent: February 13, 2024Assignee: TDK CorporationInventor: Matthias König
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Patent number: 11892423Abstract: A sensor including a detection film formed from a resin composition, a first electrode provided on a first surface of the detection film, and a second electrode provided on a second surface of the detection film, wherein the first surface of the detection film includes a rough surface having fine irregularities with a root mean square roughness (Rq) of 0.3 ?m to 3.0 ?m in a portion that is in contact with the first electrode.Type: GrantFiled: March 25, 2019Date of Patent: February 6, 2024Assignee: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Megumi Hayasaka, Yoshifumi Komatsu, Yoshihiro Harada
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Patent number: 11885727Abstract: The home device capable of gas detection is provided and includes a main body and a gas detection module. The main body has at least one inlet, at least one outlet and a gas flowing channel disposed between the at least one inlet and the at least one outlet. The gas detection module is disposed in the gas flowing channel of the main body and includes a piezoelectric actuator and at least one sensor. Gas is inhaled into the gas flowing channel through the inlet by the piezoelectric actuator, is discharged out through the outlet, and is transported to the at least one sensor to be detected so as to obtain gas information.Type: GrantFiled: December 24, 2020Date of Patent: January 30, 2024Assignee: MICROJET TECHNOLOGY CO., LTD.Inventors: Hao-Jan Mou, Yung-Lung Han, Chi-Feng Huang, Chun-Yi Kuo, Yi-Ting Lu, Chang-Yen Tsai, Wei-Ming Lee
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Patent number: 11881093Abstract: A vehicle system includes: smoke sensors located at different locations within a passenger cabin of a vehicle and configured to measure amounts of cigarette smoke at the locations, respectively, within the passenger cabin of the vehicle; and a smoking module configured to, based on the measured amounts of cigarette smoke, determine that: a smoking event occurred at a first location within the passenger cabin; and the smoking event did not occur at a second location that is different than the first location within the passenger cabin of the vehicle.Type: GrantFiled: July 7, 2021Date of Patent: January 23, 2024Assignee: DENSO International America, Inc.Inventors: Sibu Varughese, Martín Nespolo, Thomas Krzyzak, Gareth Webb, Wilson Yim, Matthew Johnson
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Patent number: 11879813Abstract: A leak detection device includes a body having at least one fluid input that receives a fluid leak, at least one drain fluidly coupled with a container, and at least one sensor conduit input fluidly coupled with at least one sensor. The fluid input is located above the drain but below the sensor conduit input. The body includes an internal conduit that is fluidly coupled with and extends between the fluid input, the drain, and the sensor conduit input. The internal conduit includes a lower branch that extends below the fluid input to the drain. The internal conduit includes an upper branch that separately extends in the body above the sensor conduit input to the drain. The lower branch includes a reduced flow portion below the fluid input and the sensor conduit input but above the drain.Type: GrantFiled: September 10, 2021Date of Patent: January 23, 2024Assignee: TRANSPORTATION IP HOLDINGS, LLCInventors: Shawn Gallagher, Pisey Leute, Manuel Licon Flores, Jesse Brigden, Sudheer Khanapure
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Patent number: 11874205Abstract: A gas chromatograph comprises a sample gas generation unit, separation column, and detector. Multiple gas sources serve as carrier gases to transport sample gas to the separation column. A switching component connects the gas sources to the sample gas generation unit based on user-input information. This information is stored in a gas type memory, which aids a gas type identification component in determining the carrier gas type by monitoring the switching component's status and referring to the stored data.Type: GrantFiled: December 30, 2020Date of Patent: January 16, 2024Assignee: SHIMADZU CORPORATIONInventors: Ayaka Kisaka, Yasuhiro Kimoto, Yu Nagao
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Patent number: 11852617Abstract: A thermal desorption tube collection system uses a thermoelectric cooler to collect and concentrate gas samples. In some modes, the operation of the cooler is reversed to flow the concentrated sample directly into a separator such as a gas chromatography system. Components resolved in time by a thermal desorption separator accumulate in a sample cell and are analyzed by electromagnetic radiation-based spectroscopic techniques. Also presented are methods for analyzing biogas samples.Type: GrantFiled: April 27, 2022Date of Patent: December 26, 2023Inventors: Martin L. Spartz, Adam R. Klempner, Kelly Renee McPartland
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Patent number: 11852606Abstract: The gas sensor includes a sensor element, an element sealing member, a lead wire, a connector, an outer tube, and a grommet. The sensor element has, in the vicinity of a rear end thereof, a surface on which an electrode pad is formed. The element sealing member is configured to hold part of the sensor element. The connector is configured to hold the portion of the sensor element in which the electrode pad is formed, and to electrically connect the electrode pad and the lead wire. The outer tube is configured to be fixed to the element sealing member, and to surround the connector. The grommet is configured to be attached to a rear end of the outer tube, and to allow the lead wire to extend therethrough. A protruding portion is formed on a rear end face of the connector and is in contact with the grommet.Type: GrantFiled: March 26, 2021Date of Patent: December 26, 2023Assignee: NGK INSULATORS, LTD.Inventor: Hiroki Adachi
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Patent number: 11846601Abstract: A method of testing a gas includes providing a sensor including a sensing electrode that includes a catalyst comprising palladium, and a counter electrode that includes a metal catalyst. An electrolyte is disposed between the sensing electrode and the counter electrode, and an external electrical circuit connects the sensing electrode and the counter electrode. The gas is contacted with the sensing electrode in the absence of a voltage bias applied to the sensing and counter electrodes. A capacitive response is detected that is produced by the exposure of the sensing electrode to the gas in the absence of a voltage bias applied to the sensing and counter electrodes.Type: GrantFiled: May 10, 2018Date of Patent: December 19, 2023Assignee: CARRIER CORPORATIONInventors: Zhiwei Yang, Lei Chen
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Patent number: 11846747Abstract: Devices, systems, and methods for sampling of gases to determine information regarding leaks are disclosed. Balanced sampling can be achieved by application of an inlet having a gas permeable membrane covering the opening. Extending the opening for a length can provide additional coverage for gas sampling. Connection of gas sampling instruments with analysis systems can determine leak information for use in remedying leaks, for example, from industrial equipment such as pipelines.Type: GrantFiled: August 23, 2019Date of Patent: December 19, 2023Assignee: ABB Schweiz AGInventor: J. Brian Leen