Abstract: In a refillable injection device for use with a dilation catheter, a large bore syringe is used to refill a small bore syringe without disconnecting the syringe assembly from the catheter. A one-way valve prevents fluid from moving in the opposite direction. Movement of the small bore syringe plunger produces a high pressure, low volume flow and can be repeated if necessary after the small bore syringe is refilled. Subsequent movement of the large bore syringe plunger produces a low pressure, high volume flow.

Abstract: An expandable and deformable intraluminal vascular graft is expanded within a blood vessel by an angioplasty balloon associated with a catheter to dilate and expand the lumen of a blood vessel. The graft may be a thin-walled tubular member having a plurality of slots disposed substantially parallel to the longitudinal axis of the tubular member.

Abstract: The present invention provides a variable diameter catheter which is folded in a longitudinal manner in order to reduce the diameter for convenient and less traumatic insertion into a body orifice. The fold in the catheter is maintained by a slidably removable external sheath which aids in insertion of the catheter and in dispersion of an anti-infective medication. Once the catheter is placed in the body orifice, the external sheath is removed. The present invention is also directed to the external sheath.

Abstract: A removable U.V. light array assembly for use in a photoactivatable agent, patient treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: A fluid T-coupling comprising a through fluid flow path, and an intersecting vent path, wherein the vent path is integrally molded within the filtered bayonet connector to be used with an aspirator to control the level of vacuum communicated to an irrigation/aspiration handpiece during eye surgery.

Abstract: The angiographic catheter includes a long generally flexible portion of a first material, an intermediate portion of the first material and a second material that is more flexible than the first material and a tip portion of the second material. The long body portion has a first exit opening having a stream trajectory directed toward the exit stream trajectory from the tip member exit for stream breakup and mixing. A reaction exit is directed in the opposite direction of the first exit opening.The generally long body portion with a curved end portion with a first end curve of generally circular shape about a center that is connected to the end of the long body with a compound curve connected to the end of the first end curve and having a member positioned generally parallel to the long body portion with the distance between parallel members generally less than to the radii of the generally circular shape.

Abstract: A container for intravenous fluid has a triangular cross-section to permit improved utilization of space during packaging of several containers in boxes or cartons, and a first opening sealed by a membrane seal which can be pierced with the spike of a conventional intravenous set. A second opening of the container is surrounded with a neck portion forming a joint to which an intermediate member is pivotably mounted. The intermediate member includes a hollow cylindrical portion having two circumferential ribs which are adapted to hold the neck of a standard small vial containing solid antibiotics and the like. The intermediate member also includes an internally mounted hollow spike so that the seal of the antibiotic vial is penetrated by the spike when the vial is mounted to the intermediate member. The duct of the spike of the intermediate member is not aligned with the second opening of the container until the intermediate member is rotated or pivoted into an extreme position.

Abstract: An improved catheter assembly is provided wherein a cannula depends from a catheter body having a first passageway therethrough communicating with the cannula through which an introducer needle may be introduced and removed. The assembly is provided with a second passageway communicating with the cannula through which a fluid may be introduced. A moveable means is provided disposed across the first passageway and moveable from a first position to a second position. The moveable means is provided with a duct passing therethrough, the duct being coaxial with the first passageway when the moveable means are in a first position to allow the introduction of removal of the introducer needle. Thereafter, the moveable means are adapted to be moved into a second position in which the access of the duct is displaced to be non-coaxial with the first passageway, and hence out of communication therewith and with the moveable means in the catheter body cooperating to seal the duct from the first and second passageways.

Abstract: An expandable intraluminal vascular graft is expanded within a blood vessel by an angioplasty balloon associated with a catheter to dilate and expand the lumen of a blood vessel. The graft may be a wire mesh tube.

Abstract: The repository probe or drug dispenser consists of a tube which is divided into a probe head and a probe end part. In addition, a series of medicine carriers are disposed in the probe head which contain active ingredients and which have an axial length of at most three times the outside diameter of the tube. In addition, openings are provided in the tube transversely of each medicine carrier for the passage of fluids. Joint zones are provided between the segments of the tube in which the medicine carriers are placed. Because of the limitation on the axial length of the medicine carriers and the joint zones, the flexibility of the probe head between the relatively stiff medicine carriers is increased without distortion or a closing of the openings to the medicine carriers when deflecting the probe.

Abstract: A improved blood flow conduit provided with external inflatable balloons and having rigid end portions for facilitating insertion into blood vessels and means for detecting pulsatile flow in the conduit and excessive pressure in the balloons.

Abstract: A surgical clamp for clamping a blood vessel and preferably made of a single piece of plastic material is provided with a hinge element flexibly connecting one end each of an upper and lower clamping arm at a spaced distance. The other end of one of the clamping arms has a locking pawl flexibly connected thereto. A mating locking mechanism flexibly connected to the other of the clamping arms engages a latch pin on the locking pawl when the clamping arms are brought together. The four hinge points, including the point of juncture between latch pin and the locking mechanism, are arrayed in a parallelogram configuration which provides for parallel movement and automatic self adjustment of the distance between the clamping arms as the clamping arms are brought together to clamp the blood vessel. Combined flexible wall andlocking mechanism elements prevent the blood vessel from being dislodged after the clamping operation, and provide ease of application of the clamp to the blood vessel.

Abstract: The nipple (1) affixed to a bottle of a nursing infant (2) by means of ring (3) comprises a semi-rigid internal membrane (5) which limits the chamber reservoir (11). Said reservoir extends by means of a lactiferous duct which ends in an opening (9) normally closed by zone (8) of the thin elastic membrane (7) which covers internal membrane (5). During suction, zone (8) of the membrane (7) swells as it becomes filled with liquid from the lactiferous duct, expelling of the liquid into the mouth being then obtained by pinching of teat (8) between the lips, and the ejection of the liquid through opening (10) which then is uncovered.

Abstract: A non-reflective instrument comprising a metallic substrate and a coating selected from the group consisting of Al.sub.2 O.sub.3, Al.sub.2 O.sub.3 /TiO mixtures, Al.sub.2 O.sub.3 /Cr.sub.3 O.sub.2 mixtures and WC/Co mixtures.

Abstract: A device is provided for applying flexible fasteners to tissue to close a wound or incision. The device has a front housing mounted for rotation relative to a rear housing. A needle projects laterally from the front housing. The needle is curved, hollow, and slotted for receiving a portion of a fastener. The device has a flexible pusher member and means for moving the flexible pusher member into the hollow needle to eject a fastener from the needle and into the tissue.

Abstract: In situ preservation of animal organs for transplantation is effected by establishing upper and lower blockages in a vascular conduit connected with such organs and then introducing a flushing solution into the conduit through a cannula at a flow rate sufficient to provide a renal flush of about 60 to 70 cc/100 g/min and until the core temperature of the organs being removed has been lowered to at least about 22.degree. C. A particular cannula assembly and flushing kit also is provided.

Abstract: A urine drainage bag having an outlet tube housing a microcidal tube is disclosed. The microcidal tube is manufactured from polymeric materials capable of absorbing and releasing antimicrobial substances in a controllable sustained time release mechanism, activated upon contact with droplets of urine, thereby preventing the retrograde migration of infectious organisms into the drainage bag.

Abstract: This invention relates to steerable catheters. More particularly, this invention relates to steerable catheters comprising a flexible catheter comprising a spring coil body defining a lumen, the spring coil body having a flexible covering thereon; a deflection wire, the distal end of the deflection wire being attached to the distal end of the spring coil body; and control means attached to the proximal end of the catheter, the proximal end of the deflection wire extending through the control means and the control means having a torque means which fixedly engages said deflection wire.

Abstract: A composition of matter comprising a drug, a neutral hydrogel and an ionic hydrogel. The composition can be administered from a delivery system to a biological receptor over time.

Abstract: In this needleless injection instrument, the piston pump (17) for the medium to be injected is connected to a drive motor (18). On the motor housing (1) of the drive motor, an operating element (2) is fitted displaceably and a stroke counter (7) for counting the applications is arranged. To the free shaft end (11) of the stroke counter, a control cam (6) is fixed which engages with a control pin (4) supported on a control roll (3) which is located in the operating element (2) for the drive motor (18).