Abstract: An adhesive pad for use with a hemostasis device comprising a footplate having a top surface and a receiving device positioned on the footplate, the adhesive pad comprising: (1) a flexible backing layer having a bottom surface, a central portion having an opening, a first side portion, and a second side portion; (2) an adhesive layer applied to the bottom surface of the backing layer; and (3) a release layer removably secured to the adhesive layer. The opening in the central portion of the backing layer is sized to fit the receiving device of the hemostasis device, and the adhesive layer applied to the bottom surface of the first and second side portions of the backing layer is configured to adhere to and extend beyond the top surface of the footplate.

Abstract: A tissue specimen retrieval bag assembly includes a tissue specimen bag having an open proximal end and a closed distal end, the proximal end including a cuff defined therein and extending therearound. A flexible bag brim is disposed within the cuff, the flexible bag brim transitionable between a first, collapsed configuration and a second, expanded configuration. The flexible bag brim includes a D-Shaped cross section configured to facilitate both furling the tissue specimen bag onto itself around the bag brim when the bag brim is disposed in the second, expanded configuration and securing the tissue specimen bag in a desired furled configuration. The flexible bag brim defines a cavity therein configured to facilitate compression thereof and to facilitate handling of the bag brim by a surgical instrument.

Abstract: Apparatus and methods are provided for flaring a stent deployed within a branch vessel including an ostium communicating with a main vessel, a first end of the stent extending at least partially from the branch. A catheter is provided that includes a balloon having a reinforced region adjacent an unreinforced region. When the balloon is positioned at a desired location, e.g., within a stent, prosthetic valve, or other tubular prosthesis, the balloon may be inflated to a first pressure causing the reinforced and unreinforced regions to expand substantially simultaneously. Upon inflation of the balloon beyond the first pressure, the reinforced region of the balloon remains at the first diameter and the unreinforced region continues to expand, e.g., to flare one or more ends of the prosthesis.

Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a handle attached to the proximal end of the shaft; and an end effector attached to the distal end of the shaft; wherein the shaft comprises a flexible portion, a first articulating portion and a second articulating portion, wherein the flexible portion extends distally from the handle, the first articulating portion extends distally from the flexible portion, and the second articulating portion extends distally from the first articulating portion; wherein at least one articulation cable extends from the handle to the first articulating portion, such that when tension is applied to the at least one articulation cable, the first articulating portion deflects; wherein a plurality of articulation cables extend from the handle to the second articulating portion, such that when tension is applied to at least one of the plurality of articulation cables, the second articulating portion d

Abstract: An in-vivo indwelling instrument in which a stretch resistant member or a resin tip at a distal end part of a coil does not easily stray from the coil, a delivering system for the in-vivo indwelling instrument, and a method for producing the in-vivo indwelling instrument is disclosed. An in-vivo indwelling instrument includes: a coil that is formed by winding a wire; a resin tip connected to a distal end part of the coil; and a stretch resistant member that is provided in a lumen of the coil and is connected to the resin tip. The coil includes a gap portion, and a part of the resin tip exists in the gap portion.

Abstract: An atrial appendage closure device is provided that includes an insertion rod having a first end and a second end. An occluding member having an outer surface and an inner surface is connected to the first end of the insertion rod. The occluding member is moveable between a retracted position and a deployed position such that, in the deployed position, the occluding member is configured to provide a seal between a left atrial appendage and a left atrium of a heart. An anchoring member is further connected to the insertion rod and is configured to slide along the insertion rod to secure the device to a wall of a left atrial appendage. Methods for occluding a left atrial appendage that make use of the closure devices are also provided.

Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.

Abstract: A surgical device is provided.

Abstract: Various devices, systems, and methods that can be used in the treatment of obesity and related illnesses are disclosed. In some instances, the cecum of an obese patient is distended to a pathophysiological size for a therapeutically effective period. The distention may be achieved by introduction of an object that is of foreign origin relative to the body of the patient into the cecum of the patient. In some instances, the distention is achieved by a medical device that transitions from an undeployed state, in which the medical device is introduced into the cecum of the patient, to an expanded state in which the medical device distends the cecum by an amount sufficient to trigger a colo-gastric brake in the patient.

Abstract: A reposable surgical clip applier including a clip cartridge assembly releasably engagable within a shaft assembly of the surgical clip applier.

Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a monopolar knife assembly attached to the distal end of the shaft, the monopolar knife assembly comprising a knife; a handle attached to the proximal end of the shaft; wherein the shaft comprises a flexible portion and an articulating portion, wherein the flexible portion extends distally from the handle and the articulating portion extends distally from the flexible portion; wherein at least one articulation cable extends from the handle to the articulating portion, such that when tension is applied to the at least one articulation cable, the articulating portion deflects; wherein an actuation element extends through the shaft from the handle to the knife, such that when the actuation element is moved, the knife is moved; and wherein the actuation element transmits electrical power from the handle to the knife.

Abstract: A tissue removing catheter includes an apposition mechanism that selectively imparts an axially compressive load on the catheter body to bend the catheter and urge a tissue-removing element toward a blood vessel wall. The apposition mechanism can include one or more adjustment lines and an adjustment mechanism for selectively tensioning one of the adjustment lines to impart the compressive load on the catheter body. Two adjustment lines can have diametrically opposed positions and be wound onto a spool of the adjustment mechanism in opposite directions so that rotation of the spool simultaneously shortens one adjustment line and lengthens the other. The catheter body can have a more flexible bending segment adjacent the tissue-removing element to promote bending near the tissue-removing element operative to urge the tissue-removing element in apposition with the blood vessel.

Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.

Abstract: A surgical instrument system includes a main body having a handle and a drive assembly. The drive assembly includes a plurality of gears and rotation transfer mechanisms for translating the movements of the handle into a mechanical force. A surgical tool having a tool body, an elongated shaft and an effector assembly is removably engaged to the main body of the system. The tool body houses a transfer gear assembly for engaging the drive assembly. A plurality of control wires extends from the transfer gear assembly to the effector assembly. The effector assembly includes a frame member having a pair of arms positioned along the distal end. The arms functioning to selectively open, close and move omnidirectionally based on an input of the handle.

Abstract: Provided are an end tool of a surgical instrument and a method of manufacturing the same, and more particularly, an end tool of a surgical instrument that may be manually operated to be used in laparoscopic surgery or other various surgery and a method of manufacturing the end tool, wherein a load applied to a pin (rotary shaft) and the pulley is appropriately distributed such that the pulley may be sufficiently rotated and at the same time, an overall durability may be improved.

Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.

Abstract: The present disclosure describes filter devices for deployment to body vessels where clots or emboli may need to be captured, particularly the vena cava. The filter device is of unitary construction, having been cut from a substantially planar sheet of a metal, in some instances a shape memory metal. The device has a construction including a plurality of petals, the petals containing an inner rib which curves in the deployed state. A method of making a filter device is also disclosed.

Abstract: A method includes passing a first flexible strand through a tissue section by a first needle coupled to a driver. The driver includes a longitudinal body defining an opening at a distal end. The first needle is positioned in the opening. A first hole is formed through a bone. The first flexible strand is passed through the first hole using a strand retriever. The strand retriever includes a body having a first longitudinal tube extending therefrom and a first snare slideably deployable from the first longitudinal tube. The first longitudinal tube is positioned from a first side of the bone in the first hole and the first snare is deployed on a second side of the bone. The first snare passes the first flexible strand through the first hole in the bone. The tissue section is secured to the bone using the first flexible strand.

Abstract: A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

Abstract: Delivery systems with tethers for prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, an elongated catheter body, a capsule carried by the elongated catheter body and carrying a prosthetic heart valve device, and a cinching member slidably disposed within the capsule. The delivery system can further include a plurality of tether elements coupled to the prosthetic device and extending through the cinching member and the catheter body. Retraction of the tether elements can urge at least a portion of the prosthetic device into a distal end portion of the cinching member to resheathe at least a portion of the prosthetic device and allow repositioning of the prosthetic device relative to the native valve after a portion of the prosthetic device has contacted tissue of a native valve.