Abstract: Method, system, and computer program product for personalized medical content recommendation are provided. The method may comprise having a patient medical profile; having a concept or relationship relating to the patient medical profile; obtaining medical content relevant to the concept or relationship; determining a score of the concept or relationship to the patient medical profile; enhancing the score with a context score based on the values of attributes of the concept or relationship in the patient medical profile; enhancing the score with an additional knowledge score based on knowledge of the concept or relationship additional to the medical content; recommending medical content with respect to a patient medical profile based on the enhanced scores. The method may also include providing an explanation of a medical content recommendation based on a matching concept or relationship.