Abstract: The present invention relates to compositions for making up and/or caring for the skin and/or the lips, comprising at least one fatty phase comprising:—at least one hydrocarbon-based resin with a number-average molecular weight of less than or equal to 10 000 g/mol,—at least one hydrocarbon-based block polymer,—from 11% to 80% by weight of non volatile non phenylated silicone oil(s) having at least a dimethicone part, relative to the total weight of the composition, and—from 1% to 80% by total weight of non volatile hydrocarbonated apolar oil(s), relative to the total weight of the composition.
Abstract: The invention pertains to implantable medical devices for controlled delivery of therapeutic agents. Some devices according to the invention have a titanium reservoir, and a porous titanium oxide based membrane to control the rate of release of the therapeutic agent. The reservoir contains a formulation of the active agent, including a stabilizer for the active agent, wherein the stabilizer is provided in an extended release configuration.
Abstract: A process for the preparation of an erodible tamper-resistant dosage form that comprises a therapeutic agent-substrate complex embedded in a thermo-formable matrix, such that the complex includes at least one therapeutic agent bound to at least one substrate to form the therapeutic agent-substrate complex. The at least one substrate is being selected from a polyelectrolyte, an organic counter-ion, a pharmacologically inert organic component of a prodrug, an inclusion compound and an inorganic adsorbent; and the thermo-formable matrix includes one or more thermoplastic polymers and optionally at least one pharmaceutical additive. The dosage form provides resistance to intentional or unintentional tampering such as chewing, crushing and grinding, and volatilization.
Type:
Grant
Filed:
March 2, 2016
Date of Patent:
July 3, 2018
Assignee:
ExxPharma Therapeutics LLC
Inventors:
Isaac Ghebre-Sellassie, Hibreniguss Terefe