Patents Examined by Glennon H. Hollran
  • Patent number: 5321160
    Abstract: A process for producing an ethylenamine, which comprises reacting ammonia and/or an ethylenamine with an ethanolamine in the presence of hydrogen to obtain an ethylenamine having an increased number of ethylene chains over the ammonia and/or the ethylenamine used as the starting material, wherein a catalyst comprising Ni, X and M elements wherein X is Re, Ir, Pt or Pd, and when X is Re, Ir or Pb, M is at least one rare earth element selected from the group consisting of scandium, yttrium, praseodymium, neodymium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium and lutetium, and when X is Pd, M is at least one member selected from the group consisting of rare earth elements is used for the reaction.
    Type: Grant
    Filed: July 29, 1992
    Date of Patent: June 14, 1994
    Assignee: Tosoh Corporation
    Inventors: Toshio Hironaka, Noritaka Nagasaki, Yasushi Hara
  • Patent number: 5112596
    Abstract: The permeability of the blood-brain barrier to endogenous or exogenous neuropharmaceutical or diagnostic agents in an individual's blood stream is increased by administering a bradykinin agonist of blood-brain barrier permeability, such as N-acetyl [Phe.sup.8 (CH.sub.2 -NH)Arg.sup.9 ] bradykinin, to the individual. The bradykinin agonist of blood-brain barrier permeability is co-administered with the agent of interest into a blood vessel such as a vein. This co-administration allows the agent of interest to pass the blood-brain barrier into the brain compartment.
    Type: Grant
    Filed: April 23, 1990
    Date of Patent: May 12, 1992
    Assignee: Alkermes, Inc.
    Inventor: Bernard Malfroy-Camine
  • Patent number: 4749716
    Abstract: The present invention relates to one of the two geometrical isomers (a compound defined as I-A isomer in the description below) of a triazole compound represented by the formula (I) or (II), ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl or 2-propynyl group, R.sub.2 is a C.sub.1 -C.sub.6 alkyl, cyclopropyl or 1-methylcyclopropyl group, R.sub.3, which may be the same or different, is a halogen atom, a C.sub.1 -C.sub.4 alkyl, halogen-substituted C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.4 alkoxy, phenoxy, phenyl, cyano or nitro group, n is an integer of 0 to 3, and the term, halogen, means chlorine, bromine and fluorine atoms, its salts, production thereof and a fungicide, herbicide and/or plant growth regulator for agriculture and horticulture containing said compound as an active ingredient.
    Type: Grant
    Filed: September 4, 1985
    Date of Patent: June 7, 1988
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yuji Funaki, Hirofumi Oshita, Shigeo Yamamoto, Shizuya Tanaka, Toshiro Kato
  • Patent number: 4204065
    Abstract: Soft quaternary surface active agents having the formula: ##STR1## wherein >N represents a tertiary open chain or cyclic aliphatic amine; wherein >N represents an unsaturated amine; wherein R represents a member selected from the group consisting of a hydrogen atom, a C.sub.1 -C.sub.20 open chain or cyclo alkyl group, a C.sub.1 -C.sub.20 alkoxyalkyl group, a C.sub.1 -C.sub.20 acyloxyalkyl group, a C.sub.1 -C.sub.20 haloalkyl group, a C.sub.1 -C.sub.20 carboxyalkyl group, an aryl group, and a substituted aryl group, whose substituents are selected from the group consisting of a halogen atom, an O--C.sub.1 -C.sub.4 alkyl group, an O--C.sub.1 -C.sub.8 acyl group, a nitro group, a carboxyl group, and a carboethoxy group; wherein R.sub.1 represents a C.sub.9 -C.sub.22 straight or branched alkyl group, a --(CH.sub.2).sub.n -- ##STR2## group, wherein R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each selected from the group consisting of a hydrogen atom, a methyl group or an ethyl group, a C.sub.0 -C.sub.
    Type: Grant
    Filed: December 13, 1978
    Date of Patent: May 20, 1980
    Assignee: Interx Research Corporation
    Inventor: Nicolae S. Bodor