Abstract: Compounds of the formula ##STR1## and pharmaceutically acceptable salt thereof, wherein R.sup.2 is selected from hydroxy and lower alkoxy, R.sup.5 is lower alkyl, and R.sup.11 and R.sup.12 are independently selected from hydrogen, halo, hydroxy, methoxy, and lower alkyl, are selective .alpha..sub.2 adrenergic receptor antagonists useful in the treatment of glaucoma.
Type:
Grant
Filed:
March 26, 1990
Date of Patent:
February 4, 1992
Assignee:
Abbott Laboratories
Inventors:
John F. DeBernardis, Robert E. Zelle, Fatima Z. Basha
Abstract: This disclosure relates to N-substituted benzothiazolines and N-substituted benzoxazolines which are useful as plant growth regulants. This disclosure further relates to plant growth regulant compositions containing such N-substituted benzothiazolines and N-substituted benzoxazolines and to methods of regulating the growth of leguminous plants employing such compounds and compositions.