Patents Examined by Grace C. Hsu
  • Anti-stress composition
    Patent number: 6265450
    Abstract: An anti-stress composition having for its active ingredient astaxanthin and/or its ester. This composition can be in the form of a pharmaceutical, functional food, food or beverage and so forth.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: July 24, 2001
    Assignees: Suntory Limited, Itano Refrigerated Food Co., Ltd.
    Inventors: Sumio Asami, Zhi-bo Yang, Eiji Yamashita, Hayao Otoze
  • Arachidonic acid metabolite, 16-HETE
    Patent number: 6140364
    Abstract: The present invention provides methods and products for inhibiting neutrophil adhesion and neutrophil aggregation. The invention includes a method for treating a subject to inhibit neutrophil adhesion and neutrophil aggregation by administering 16-hydroxyeicosatetraenoic acid (16-HETE) to the subject. 16-HETE is an arachidonic acid metabolite. The invention also includes a pharmaceutical preparation of 16-HETE. Methods and products are also provided for treating thromboembolic stroke. The method involves the administration of 16-HETE in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke. Preferably, the 16-HETE is 16(R)-HETE and the thrombolytic agent is tPA. The product is a pharmaceutical preparation of 16-HETE and a thrombolytic agent and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 26, 1999
    Date of Patent: October 31, 2000
    Assignees: The University of Vermont and State Agricultural College, New York Medical College, Board of Regents The University of Texas System
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy