Abstract: Racemic hernandulcin, a sesquiterpene, possesses a sweetness intensity about three orders of magnitude greater than that of sucrose. It is non-mutagenic and non-toxic under conventional assay procedures. In addition to attractive utility in foods, beverages and pharmaceutical compositions, it affords a low-cariogenic, essentially non-nutritive sweetening agent for inclusion in oral hygiene products.
Type:
Grant
Filed:
August 16, 1984
Date of Patent:
February 28, 1989
Assignee:
Board of Trustees, University of Illinois
Inventors:
Alan D. Kinghorn, Cesar M. Compadre, John M. Pezzuto
Abstract: Ester derivatives of N-substituted and N,N-disubstituted aminopropanoloxy flavones in which the aminopropanoloxy side chain is inserted at either the 5-, 6-, 7- or 8-position of the flavone nucleus, and N-substituted and N,N-disubstituted aminopropanoloxy flavones in which the aminopropanoloxy side chain is inserted at the 8-position of the flavone nucleus; useful as anti-dysrhythmic agents.