Patents Examined by H. Sarah Park
  • Patent number: 11998583
    Abstract: A Fructus Forsythiae and Radix Astragali compound preparation, and a preparation method therefor and a use thereof is provided. Traditional Chinese medicine formulation components consist of the following raw materials or raw material extracts in parts by mass: 9-11 parts of Flos Lonicerae, 9-11 parts of Fructus Forsythiae, 9-11 parts of Radix Scutellariae, 9-11 parts of Herba Artemisiae Annuae, 9-11 parts of Radix Astragali, 9-11 parts of stir-fried Rhizoma Atractylodis Macrocephalae, 9-11 parts of Herba Pogostemonis, 5-7 parts of Radix Saposhnikoviae, 9-11 parts of Radix Ophiopogonis, and 5-7 parts of Radix Glycyrrhizae. The components can be made into an oral liquid, a granule, a dissolved medicine, or a tablet. Further disclosed is a use of the Fructus Forsythiae and Radix Astragali compound preparation in preparation of medicines for preventing and/or treating a viral influenza disease.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: June 4, 2024
    Inventors: Xiaosong Gu, Chunkang Tang, Leilei Gong, Yu Zhang, Qiong Cheng, Xiaoming Yang, Xiaomin Wang
  • Patent number: 11992513
    Abstract: A traditional Chinese medicine composition for treating hand-foot syndrome after targeted drug treatment is mainly prepared from the following components by weight: 20-50 parts of Radix Sophorae Flavescentis, 20-50 parts of Herba Taraxaci, 20-50 parts of Flos Chrysanthemi Indici, and 20-50 parts of Herba Cum Radice Violae Yedoensitis, 20-50 parts of Rhizoma Smilacis Glabrae, 30-60 parts of Radix Astragali Seu Hedysari, 10-35 parts of Kochia scoparia (L.) Schrad, 10-45 parts of Carthamus tinctorius L., 15-45 parts of Cortex Radicis Dictamni Dasycarpi, 5-15 parts of Herba Ephedrae, 5-25 parts of Angelica sinensis, 5-25 parts of Rhizoma Ligustici Chuangxiong, 10-30 parts of Radix Rehmanniae, 5-15 parts of Ramulus cinnamomi, 10-30 parts of Cynanchum otophyllum Schneid, 5-15 parts of Semen Sinapis Albae, 5-20 parts of Arisaema heterophyllum Blume, 5-20 parts of Typhonium blumei Nicolson & Sivadasan, and 10-40 parts of Radix Glycyrrhizae.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: May 28, 2024
    Inventors: Qi Dai, Kunshan Chen, Xiaoqi Zhou
  • Patent number: 11992579
    Abstract: The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using.
    Type: Grant
    Filed: November 27, 2020
    Date of Patent: May 28, 2024
    Assignee: ACell, Inc.
    Inventors: Chandra M. Valmikinathan, Nikhil Niraj Gheewala, Brent Donald Young, Thomas Wayne Gilbert
  • Patent number: 11969589
    Abstract: A proto-device for implantation into soft tissue comprises an oblong device body, biodegradable microfibres adhesively attached to the body, a rigid matrix of biocompatible material enclosing the body and the microfibres. The biocompatible material is dissolvable and/or degradable in aqueous body fluid at a rate substantially superior to the rate of microfibre degradation. The proto-device is one of proto-microelectrode, proto-optical fibre, proto-polymer tube for drug delivery, proto-electrical lead, proto-encapsulated electronics. Also disclosed are uses of the proto-device and methods for its implantation and manufacture.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: April 30, 2024
    Assignee: NEURONANO AB
    Inventor: Jens Schouenborg
  • Patent number: 11951116
    Abstract: A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: April 9, 2024
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Patent number: 11944716
    Abstract: A composition includes a plurality of particulate coated hydrogel microparticles, each of the microparticles including a hydrogel inner core and a particulate shell defined by a plurality of solid nanoparticles, the particulate shell inhibiting aggregation of the microparticles in an aqueous medium and being permeable to allow release of agents from the hydrogel inner core.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: April 2, 2024
    Inventors: Eben Alsberg, Rui Tang
  • Patent number: 11938456
    Abstract: Process for the preparation of layered particles are provided. Layered particles prepared by such processes are also provided.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: March 26, 2024
    Assignee: Delphi Scientific, LLC
    Inventor: Thomai Panagiotou
  • Patent number: 11896706
    Abstract: The present disclosure relates to a composition for preventing hair loss or promoting hair growth, which contains a mixture of cucumber, eggplant and snail extracts as an active ingredient. The composition according to the present disclosure, which contains a mixture of cucumber, eggplant and snail extracts as an active ingredient, has been confirmed to increase the expression of hepatocyte growth factor (HGF), keratinocyte growth factor (KGF) and insulin-like growth factor 1 (IGF-1) in dermal papilla cells which are known to play a critical role in the induction of new hair follicles and maintenance of hair growth, exhibit hair-growing effect comparable to that of minoxidil in a hair growth test for depilated 6-week-old C57BL/6 mice, and exhibit hair loss-improving effect in a clinical test for human. Accordingly, it can be usefully used as a cosmetic composition or a pharmaceutical composition for external application to skin for preventing hair loss or promoting hair growth.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: February 13, 2024
    Assignee: OGADAL INC.
    Inventors: Dong wan Lee, Seoung Ok Kim, Haseop Lee
  • Patent number: 11890371
    Abstract: The present invention relates to biocompatible protein-based particles and their methods of preparation and use. More specifically the present invention relates protein-based particles including protein matrix, spread matrix and/or biocoacervate materials derived from one or more biocompatible purified proteins combined with one or more biocompatible solvents that are used to replace or repair tissue and/or bone in treatments for spinal disc(s), joint(s) (e.g. knee, hip, finger, ankle, elbow, shoulder . . . ) and organ(s) (e.g. bladder, lips, vagina, penis, urethra . . . ). In various embodiments of the present invention the protein-based particles may also include one or more pharmacologically active agents and/or one or more additives.
    Type: Grant
    Filed: December 26, 2008
    Date of Patent: February 6, 2024
    Inventor: David B. Masters
  • Patent number: 11883458
    Abstract: A composition for alleviating or treating asthma is proposed. A composition for alleviating or treating asthma contains, as an active ingredient, a concentrate obtained by distilling an extract obtained by extracting a herb medicine complex containing dried Rehmanniae radix, Cyperus rotundus L., Paeonia lactiflora Pall., Zingiber officinale Roscoe, Angelica gigas root, Carthamus tinctorius L., and Glycyrrhiza uralensis Fisch., using an extraction solvent, and can be provided in the form of an oriental pharmacopuncture solution or an injection.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: January 30, 2024
    Inventor: Sung Ki Kim
  • Patent number: 11857591
    Abstract: A composition for protecting liver, protecting intestines and enhancing immunity for freshwater fish is disclosed, including the following raw materials in parts by weight: 15˜27 parts of Andrographis herba, 18˜22 parts of Isatidis folium, 10˜15 parts of Polygonum hydropiper, 8˜12 parts of Rheum palmatum L., and 8˜12 parts of Galla chinensis. And the preparation and the application of the composition are disclosed. The composition of the disclosure has the effect of resisting bacteria, scavenge free radicals, clearing heat, detoxifying, preventing and treating enteritis and the like, which can effectively improve the immunity of the freshwater fish and ensure the health of the organism.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: January 2, 2024
    Inventors: Jinjuan Wan, Hui Xue, Sheng Yuan, Aijun Xia, Yanhua Zhao, Meifang Shen
  • Patent number: 11850257
    Abstract: The present invention provides cnidimoside A for use in the treatment of urinary conditions such as overactive bladder and related syndromes. The invention also relates to methods of treatment of overactive bladder using cnidimoside A. The compound can be administered purified or as a plant extract.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: December 26, 2023
    Assignee: SAGANATURA EHF.
    Inventor: Steinthor Sigurdsson
  • Patent number: 11826459
    Abstract: An effervescent tablet that exhibits rapid disintegration is disclosed. The effervescent tablet includes an effervescent agent that includes an acid and a base, a crystalline sugar binder selected from the group consisting of crystalline dextrose, crystalline sucrose, crystalline fructose, and combinations thereof, the crystalline sugar binder being essentially free of excipients, a sweetener that includes at least one of Stevia and Monk fruit, a flavor agent that includes a gum Arabic carrier, and optionally a lubricant derived from rice hulls (e.g., a multi-component integral lubricant).
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: November 28, 2023
    Inventors: Carrie Kraling, Sarah Olson, Shayna Jilek
  • Patent number: 11819531
    Abstract: The present invention provides random copolymers containing zwitterions and one or more functional agents, and methods of preparing such random copolymers.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: November 21, 2023
    Assignee: Kodiak Sciences Inc.
    Inventors: Stephen A. Charles, D. Victor Perlroth, Lane A. Clizbe, Didier G. Benoit, Wayne To
  • Patent number: 11801280
    Abstract: The present invention relates to a drug for treating leukopenia, its preparation method and use thereof. The drug of the invention is prepared from 200-30 parts by weight of Folium Epimedii, 100-160 parts by weight of Fructus Psoraleae, 60-120 parts by weight of Radix Aconiti Lateralis Preparata (Processed), 200-300 parts by weight of Fructus Lycii, 200-300 parts by weight of Radix Astragali, 200-300 parts by weight of Caulis Spatholobi, 200-300 parts by weight of Radix Rubiae, 100-160 parts by weight of Radix Angelicae Sinensis, 200-300 parts by weight of Rhizoma Phragmitis, 100-160 parts by weight of Radix Ophiopogonis and 100-160 parts by weight of Radix et Rhizoma Glycyrrhizae. The drug of the invention comprises chemical substances with weight ratios as follows: Leucine:guanosine:psoralenoside:isopsoralenoside:calycosin-7-glucoside:liquiritin:icariin A:1,3-dihydroxyl-2-hydroxymethylanthraquinone:epimedin A:epimedin B:epimedin C:icariin:1,3,6-trihydroxy-2-methylanthraquinone:glycyrrhizic acid=(0.13-0.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: October 31, 2023
    Inventor: Min Zhang
  • Patent number: 11793850
    Abstract: Disclosed a plant-derived exosome as well as a preparation method and an application thereof in preparation of drugs or scaffolds for animal tissue regeneration therapy. The preparation method includes: soaking and infiltrating any part of a natural plant with a 2-(N-morpholine) ethanesulfonic acid buffer solution; removing a supernatant; collecting a wet treated sample; refrigerating, centrifuging and extracting the sample to obtain apoplastic fluid, wherein the soaking and infiltrating method is as follows: vacuum supply is performed within 6-24 h after soaking for 2-5 times, vacuum supply time is independently 5-15 s each time, and interval time between two adjacent times of vacuum supply is independently 10 s-1 min; and centrifuging the apoplastic fluid at an ultra-high speed to obtain the plant-derived exosome, wherein ultra-high speed centrifugation conditions are as follows: centrifugal force is not lower than 100000 g, centrifugation time is 1-7 h, and a temperature is 0-4° C.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: October 24, 2023
    Assignees: Zhejiang University, Jiangsu Nanfang Medical Co., Ltd.
    Inventors: Jianqing Gao, Liming Li, Jiachen Chen, Ping Li
  • Patent number: 11793905
    Abstract: The invention relates to a surgical or wound dressing comprising a sheet of gellan gum and an antifibrotic agent. Methods of producing dressings comprising gellan gums and biologically active agents area also produced.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: October 24, 2023
    Inventors: Liam Grover, Ann Logan, Felicity De Cogan, Gurpreet Chouhan
  • Patent number: 11786470
    Abstract: This invention provides novel solid pharmaceutical compositions and processes for the bulk production of said compositions. This invention also provides methods of using the pharmaceutical compositions in the treatment of cancer.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: October 17, 2023
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventor: Bhavishya Mittal
  • Patent number: 11786633
    Abstract: A bioink composition and a 3D bioprinted scar tissue model with the bioink composition closely replicates the physiological and architectural characteristics of naturally occurring scar tissue. The 3D bioprinted scar tissue can be used to test scar resolution treatments among others. Also provided is a method of fabricating the 3D bioprinted scar tissue along with an apparatus for bioprinting the 3D bioprinted scar tissue.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: October 17, 2023
    Inventors: Sourabh Ghosh, Shikha Chawla
  • Patent number: 11771665
    Abstract: Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O2. Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O2 entering the contact lens holder.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: October 3, 2023
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Phillip J. Dixon