Abstract: The invention encompasses the treatment of urinary incontinence, gastroesophageal reflux disease and the amelioration of skin wrinkles using biocompatible hydrophilic cationic microparticles and a cell adhesion promoter.
Type:
Grant
Filed:
March 5, 1999
Date of Patent:
January 1, 2002
Assignee:
Biosphere Medical, Inc.
Inventors:
Jean Marie Vogel, Richard Thomas, Egisto Boschetti
Abstract: A powdered pulmonary surfactant preparation containing a hydrophobic protein serving as a pulmonary surfactant is obtained by spray drying an organic solution or suspension containing a hydrophobic protein serving as a pulmonary surfactant and possibly other components. Obtained power preparations exhibit very good stability under storage, are easy to reconstitute and are also suitable for administration by inhalation.