Abstract: An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member.

Abstract: A medicament delivery device includes a body having a proximal end and a distal end, in turn comprising a distal housing part, and a medicament container holder, adapted to receive a medicament container; a dose setting drum for setting a dose when rotated in a first direction and for delivering a dose when rotated in a second direction, and a drive drum sleeve selectively operably connectable to a piston plunger for delivering a dose.

Abstract: A luer access device (LAD) and a method of attaching the same are provided to create a sterile fluid-flow path. The LAD includes a female luer connector that has an internal female split septum disposed at a proximal end thereof and is coupled to an internal surface of the LAD. A male luer connector is coupled to an external surface of the female split septum. Additionally, a male split septum is disposed within a male luer tip and seals an opening of a distal end of the male luer connector. At least one aperture is disposed through a sidewall of the distal end of the male luer connector. An internal cannula is exposed out of the female luer connector to open the female split septum upon engagement with the male luer connector.

Abstract: A method for assembling a drug delivery device that includes mounting a cartridge with a bung, the mechanism, the plunger and the spring within a housing such that a spring biases a plunger in a dispensing direction and that a drum and/or the release member is attached to the plunger attaching a tool with torque measurement capability to the drum or a release member of a dose mechanism in a state where at least one housing part is detached from further housing part; setting a dose by rotating the dose setting member in a first direction, activating a trigger and monitoring the torque applied to the drum or the release member; releasing the trigger upon detection of a predetermined change in the torque measured by the tool; and releasing the tool and closing the housing.

Abstract: A pen includes a carpule having a longitudinal axis, a first end with a dispensing opening closable by a closure part, a second end via which at least one stopper can be inserted in the direction of the longitudinal axis, and an interior that is tightly closed by the closure part and the at least one stopper. A pen housing has a central axis, receives the carpule, and has a piston rod that interacts with the at least one stopper and a drive for moving the at least one stopper within the interior of the carpule, wherein the second end of the carpule can be inserted into the housing.

Abstract: A syringe with adjustable penetration depth, comprising a tubular syringe barrel, a plunger positioned within the syringe barrel, a hub bearing a needle and attached to the syringe barrel, a movable collar having an open proximal end received over the hub, a distal end wall having an opening through which the needle protrudes, and a sidewall extending proximally from the distal end wall, the sidewall having an interior surface engaging the hub or syringe barrel, and a retaining feature on the collar engaging the hub or barrel and retaining the collar at a plurality of axial positions. The collar travels with respect to the hub along a path defined by the retaining feature on the interior surface of the sidewall engaging the hub or barrel, exposing a greater length of the needle as the collar travels toward the plunger.

Abstract: Embodiments of the disclosure may include a medical device comprising a flexible elongate member including a longitudinal axis and a tool connected to the elongate member near a pivot, wherein the tool may be configured for at least one of suction and infusion, and wherein the tool may be configured to pivot towards both sides of the longitudinal axis relative to the elongate member at the pivot.

Abstract: System and methods are provided for harvesting one or more organs, e.g., a lung from a donor body. In one embodiment, a distal end of a tubular member is introduced into the donor body's vasculature via a percutaneous access site, and the tubular member is manipulated until the distal end of the tubular member is disposed within the thoracic duct. Fluid is removed from the thoracic duct through the tubular member to a location exterior to the patient's body, and one or more organs are removed from the donor body. Optionally, one or more parameters within the thoracic duct or other parameters of the donor body may be monitored and fluid removal may be adjusted to reduce fluid accumulation within the one or more organs.

Abstract: A transdermal drug delivery device comprises needles for piercing the skin of a patient to form pores in a predefined pattern; and carriers in the same pattern that may be loaded with a drug for delivery. The carriers are applied to the pores to deliver the drug through the pores to a location beneath the surface of the skin. The carriers may remain outside the pores, be introduced into the pores after the needles have been removed, or be inserted alongside the needles while they are still in place.

Abstract: A syringe having a bonded needle, comprising a syringe body, a needle protector comprising a flexible cap, an outer sleeve, which can move along a longitudinal axis between an extended position, in which it covers the needle, and a retracted position, in which it does not cover the needle, and a collar, which is mounted with a radial clearance around an end part of the syringe body and which comprises at least one pin engaged in a guide opening of the sleeve. A portion of the flexible cap fills the radial clearance between the end part of the syringe body and the collar when the cap is mounted on the syringe, such that the collar cannot rotate around the end part of the syringe body as long as the cap is mounted on the syringe.

Abstract: A first tubular body having a first longitudinal axis extending centrally through the tubular body includes at least one delivery port extending through a wall of the first tubular body. A second tubular body having a second longitudinal axis extends through the second tubular body, the first and second longitudinal axes being displaced from each other such that an asymmetrical longitudinally extending gap is formed between an outer surface of the second tubular body and an interior surface of the first tubular body. A temperature sensor forming a thermocouple extending longitudinally within the gap between the first tubular body and the second tubular body. An inner core is positioned within the second tubular body. The inner core includes least one ultrasound element.

Abstract: A medical device useful for collecting samples of a bodily fluid, typically a vascular fluid such as blood. The subject device can also be used for infusing liquids into a patient. The fluid flow path desirably includes a forwardly projecting, rearwardly biased needle, a needle holder and a length of plastic tubing, the forwardly extending end of which is configured to function as a fluid seal to reduce the likelihood of fluid leakage during or after use. Following use, the needle is retractable from the patient by sliding a needle retraction cavity transversely into longitudinal alignment with the needle, thereby disrupting the fluid flow path and propelling the needle rearwardly so that it no longer projects from the device.

Abstract: A catheter assembly includes a catheter; a catheter hub fixed to a proximal end portion of the catheter; a hollow needle having a needle tip and disengageably located in the catheter; a needle hub fixed to a proximal end portion of the needle; a guide wire slidably located in the needle, the guide wire being longer than the catheter and having a distal end that is protrudable from the needle tip; a guide wire hub configured to support the guide wire and move the guide wire with respect to the needle in association with movement of the guide wire hub; and a movement mechanism configured to retract the guide wire hub with respect to the needle hub such that the distal end of the guide wire is housed in the needle in association with forward movement of the catheter hub with respect to the needle hub.

Abstract: Systems and methods are provided for intermittent microinfusion. A system may include a pump and an IV set that includes a y-port valve disposed below a pump interface portion of the IV tubing. The y-port valve may include an internal valve member that allows fluid to flow from the pump to a patient when no syringe is attached to the y-port. The internal valve member may be moved by the attachment of a syringe containing the medication to be infused to the y-port such that the fluid pathway from the pump to the patient is blocked and fluid from the syringe can be injected into the IV tubing between the y-port valve and the pump. The pump may retrograde pump the medication into the tubing via the y-port valve and then forward pump the medication to the patient when the syringe is removed from the y-port.

Abstract: Methods and apparatus provide treatment with a first therapeutic agent and a second therapeutic agent for an extended time. The first therapeutic agent may comprise a VEGF inhibitor and the second therapeutic agent may comprise an antiinflammatory, such as a non-steroidal anti-inflammatory, for example a cyclooxygenase inhibitor. One or more of the first therapeutic agent or the second therapeutic agent can be injected into the eye, for example injected into a therapeutic device implanted into the eye to release the injected therapeutic agent for an extended time.

Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.

Abstract: A pharmaceutical injecting device comprises a main body case, a piston, a drive mechanism, a display component, and a controller. The body case has a cartridge holder in which a pharmaceutical syringe is installed. The piston is provided movably with respect to the pharmaceutical syringe that is installed in the cartridge holder. The drive mechanism drives the piston. The controller is electrically connected to the drive mechanism. The display component is connected to the controller. The controller has a display controller. The display controller causes the display component to display a plurality of injection sites and to display at two or more injection sites selectable displays indicating that those injection sites are suitable for injection.

Abstract: Catheterization employing a cable extending from the catheter to a fixed point of attachment is performed by providing a sensor to detect rotation of the catheter about its longitudinal axis, the rotation causing the cable to form a twist. The cable extends through a cable arranger that operates to remove the twist. A controller receives signals from the sensor and generates control signals to actuate the cable arranger responsively to the signals from the sensor.

Abstract: This invention relates to an injection needle with a multi-surface penetration end which stretches soft tissue with minimal cutting upon insertion. This stretching reduces patient discomfort, the force required for urging needle into the soft tissue, and soft tissue coring. The structure of the multi-surface needle decreases the penetration footprint of the needle into the soft tissue around the needle penetration site, reducing tissue inflammation and increasing healing time. The needle also contains dual injection openings on opposing sides, behind the penetration end to discharge injected fluid over a wider area with lower pressure.

Abstract: The present invention relates to a breast pump (10) for extracting milk (30) from a human breast, comprising: a first breast receiving funnel (16) for receiving a first breast (28) of a user; a vacuum pump (20) for generating an underpressure within the first breast receiving funnel (16); and a control unit (22) for controlling the vacuum pump (20); wherein the control unit (22) is configured to operate the vacuum pump (20) in at least two different modes, an attachment mode (48) and a milk extraction mode (50); wherein in the attachment mode (48) the control unit (22) is configured to control the vacuum pump (20) to generate a constant underpressure within the first breast receiving funnel (16) allowing the user to attach the first breast receiving funnel (16) to the first breast (28); and wherein in the milk extraction mode (50) the control unit (22) is configured to control the vacuum pump (20) to generate a time-variable underpressure profile within the first breast receiving funnel (16) for extracting