Abstract: The present invention relates to viral peptides referred to as "DP107- and DP178-like" peptides. Specifically, the invention relates to isolated influenza A DP107- and DP178-like peptides which are identified by sequence search motif algorithms. The peptides of the invention exhibit antiviral activity believed to result from inhibition of viral induced fusogenic events.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
May 9, 2000
Assignees:
Trimeris, Inc., Duke University
Inventors:
Shawn O'Lin Barney, Dennis Michael Lambert, Stephen Robert Petteway