Abstract: An apparatus for the continuous production, processing and packaging of a final chewing gum product. The product is extruded as a continuous tape or ribbon of material, the material is flattened into a approximate final cross-sectional size and shape, and then inserted into a final sizing apparatus. The sizing apparatus maintains the gum product in its final cross-sectional size and shape. Thereafter, the continuous strip of final chewing gum product is scored, cut into individual pieces, and individually wrapped by a standard packaging machine. The individually wrapped pieces of gum can then be assembled into sets and packaged into packs of gum.

Abstract: A method of integrating detailed features into a spray formed rapid tool includes the steps of making a model of a desired tool and constructing a ceramic pattern as the inverse of the model. The method also includes the steps of locating at least one detailed feature insert on the ceramic pattern and thermally spraying metal material against the detailed feature insert and ceramic pattern to form the desired tool and embedding the detailed feature insert into the desired tool.

Abstract: Slideholders which are useful for manually processing tissue samples on microscope slides are described. These slideholders hold multiple slides and are designed in conjunction with specialized trays for rapidly processing the mounted tissue samples such as for immunocytochemical staining. The slideholder plus tray assemblies incorporate several useful advantages including a requirement for minimal reaction fluid volumes, ease of handling several slides concurrently, prevention of evaporation of reaction fluids, protection of the tissue from extraneous environmental contamination, and the ability to perform in situ PCR. Various aspects of the design aid in removing trapped air from the reaction fluids and in adding fluids to the tissue sample. One embodiment comprises a coverslip with a soft top which aids in prevention of tissue degradation by preventing pressure buildup during PCR.

Abstract: A filter tube for a reaction or other fluid vessel is disclosed which maintains the vessel under an inert gas atmosphere and maintains the integrity of the inert gas seal while performing filtered or unfiltered filling or filtered draining operations.

Abstract: A holder for fluorometric analysis of PCR reaction tubes comprises a longitudinal block, the block being sized to fit within a fluorometer; a cavity disposed along a longitudinal axis of the block; at least one test well within the cavity, the test well having an internal wall sized to closely receive and maintain intimate contact with a substantial portion of a single PCR reaction tube therein; the internal wall having at least one optical port therein; and a cover movably connected to the block.

Abstract: A porous material (10) is contaminated with soil (14). Optionally, the porous material is partially shielded by an impermeable layer. The contaminated porous material is packaged and shipped to a user site. The contaminated porous material is removed from the package and placed in an automated processor containing medical equipment (22). The medical equipment and porous material are subjected to a cleaning, disinfecting, or sterilizing cycle in the processor. The cleaning process is evaluated by examining the porous material with an infrared or other electronic reader (24) to determine the presence of remaining soil which has not be removed during the cleaning, disinfecting, or sterilizing cycle.

Abstract: The presence of hydrocarbons in soil is detected by immersing a soil sample in a water-miscible solvent capable of dissolving the hydrocarbons to extract hydrocarbons from the soil into the solvent. An aqueous developer is mixed into the solvent to produce a test mixture. The turbidity of the test mixture is observed to determine the presence of hydrocarbons in the soil. The aqueous developer may contain at least 0.5% salt, e.g., at least 1%, preferably 5% salt, and an emulsifier. Turbidity may be measured quantitatively by measuring light scattered at 90.degree. to a test light beam or by visual comparison to a reference scale.

Abstract: A method of constructing a fully dense metal part or a metal mold half for matin with another mold half to form a mold for casting multiple parts. Steps include placing a pattern having critical pattern surfaces in a flask having an open end. The critical pattern surfaces face upward. Other steps involve covering the critical pattern surfaces with a concentrated heat reversible gel solution added to the flask, and cooling the gel solution to form an elastic solid gel mold. Further steps include removing the flask and the pattern from the elastic gel mold, and casting a ceramic mold around the solid gel mold. In other steps the gel mold is liquified for removal from the ceramic mold and the ceramic mold is inverted so that its critical ceramic surfaces face upward.

Abstract: A roll support for use in transporting a support beam along a track having two opposed surfaces. Such roll support is particularly useful for transporting a support beam in a continuous block caster for casting metal. The invention can include mechanisms for adjusting the support beam on the roll support, devices for driving the support beam along the track and apparatus for meshing the roll support with the devices for driving.

Abstract: The invention relates to a spin beam (1) for spinning a plurality of synthetic filament yarns and a spinning machine comprising a spin beam (1) of this type. The spin beam (1) consists of an elongate rectangular solid, which is filled with a heating medium, and the underside of which mounts two parallel rows of connections (20), each connection accommodating a spin pot (17) with a spinneret (18). From a melt supply line (23), melt is distributed to a multiple spin pump (12) for each row of connections (20), and supplied therefrom via melt distribution lines (14) to the spin pots (17) of each row. The filaments emerging from spinnerets (18) are cooled and solidified below the spinnerets (18) by directing thereto a transverse flow of cooling air. The cooling air exits from a permeable wall (33) of an air distribution chamber, the permeable wall facing one row of spinnerets, and the chambers defining a common rectangular solid.

Abstract: An injection mold machine (10) is disclosed including a mold (40) having closely spaced mold cavities (56, 58). A heated sprue bushing (62) is disposed between the mold cavities so that the runners (142, 144) are relatively short. The sprue bushing has an elongated portion (78) that is narrow and fits between the mold cavities (56, 58). Two rather slender cartridge heaters (126) are disposed in holes (112, 114) formed in the elongated portion on opposite sides of the sprue opening (102) through which the molten material is injected.

Abstract: A method for collecting a sample of fluid specimen from a patient for diagnostic testing, providing a specimen collecting device comprising a hollow tubular member, an elongated foam member that is circumscribed by a hollow tubular member along a portion of its longitudinal axis. The hollow tubular member has a cross sectional area less than the uncompressed cross sectional area of the foam member so that the foam member is compressed along the circumscribed portion. Around the hollow tubular member is slidably mounted a flexible sleeve member having a first end that fits snugly around the hollow tubular member and a second end with an enlarged diameter that can surround the uncompressed foam member.

Abstract: The present invention relates to a specific cuvette, an assay method and a diagnostic test kit where samples of whole blood can be used for quantitative diagnostic testing without need for centrifugation, even though the blood components to be analyzed are in the plasma fraction. Using the method of the present invention the blood sample is converted into a plasma fraction and a cell fraction by shaking in a cuvette in the presence of a special agglutinating reagent A plasma fraction is obtained which is suitable to be used in diagnostic tests using immunometric or colormetric methods or test strips without physically removing the blood cells from the sample.

Abstract: A closure for sealing the open end of a specimen collection container from the environment is provided. The closure includes a generally spherical-shaped ball having a passageway extending therethrough, with the ball including an axle permitting rotative movement of the ball thereabout between an open position and a closed position. The closure further includes a socket mounted on the open end of the collection container, with the socket including a ball receiving internal surface having an axle-support for receiving the axle of the ball for accommodating rotative movement of the ball therein. The passageway of the ball is aligned with the open end of said collection tube when the ball is in an open position and is out of alignment with the open end of the collection container when the ball is in a closed position.

Abstract: A convertible stand and container is provided for specimen tubes and includes first and second sides each having proximate and distal portions. In a stand configuration the side proximate portions are releasably latched together and the side distal portions are folded double over the outsides of the proximate portions. A plurality of receiver proximate sections are formed between the side proximate portions. In a container configuration the side distal portions are releasably attached together and form receiver distal sections therebetween which align with the receiver proximate sections to provide receivers for containing the specimen tubes.

Abstract: A closure vessel assembly for use in laboratory work within a range of temperature from -196.degree. C. to 100.degree. C. above zero includes a vessel made of a plastic material and having a wall defining the vessel mouth, and a closure for closing the vessel. The closure has an annular sealing lip which depends from the top wall of the closure and extends into the vessel mouth when the closure is locked on the vessel. The sealing surface of the sealing lip engages the sealing surface of the vessel wall, in the locked position of the closure with the vessel, to provide a seal therebetween. The respective radii of the sealing surfaces of the sealing lip and the wall are selected so as to provide for minimum surface pressure yet sufficient sealing between the sealing surfaces, despite any deformation of the materials of the sealing surfaces during the required closing time of the vessel.

Abstract: Apparatus for removing a ceramic core from a casting in a relatively rapid manner wherein the casting and a fluid spray nozzle are disposed in a manner to expose a region of the core to a core dissolving fluid discharge of the nozzle and a core dissolving fluid is discharged from the nozzle toward the core region to contact the core region and dissolve core material therefrom and progressively from further regions of the core within the casting as they become exposed as core material is progressively removed. The discharge of fluid from the nozzle can be interrupted periodically to allow dissolved core material and fluid to drain from inside the casting or, alternately, the casting and nozzle can be relatively moved so that the casting can drain and/or forced air can be directed at the casting to this same end at a location spaced apart form the nozzle.

Abstract: In an improved method for measuring the erythrocyte sedimentation rate (ESR) a pre-evacuated test tube (T) is used to collect a blood specimen. The tube (T) is made of a material such as glass or plastics and contains an anticoagulant agent. In order to facilitate mixing of the blood sample a surfactant such as an organosilicone fluid is provided in the tube (T) as an additive.

Abstract: An integral fitting and filter assembly includes a tubular body (119) having a integral proximal fitting piece (121) and an integral distal fitting piece (122). A central passage (125) extends through the proximal fitting piece and the distal fitting piece of the body. A tubular filter assembly sleeve including a filter sub-assembly (142) and tubular extension sleeve (140) is slidably received within the central passage of the body. The filter sub-assembly includes two end caps (144, 145) and a center piece (146). The center piece is packed with a selective chemical-absorbent packing material (26), that is retained within the center piece by first and second porous plugs (148) secured within opposite ends of the center piece of the end caps.

Abstract: A sample of liquid with suspended particles is contained in a tube and subjected to a standing wave ultrasound field transverse to the tube, the standing wave exhibiting a progressive change in pressure amplitude transverse to the tube, so that particles in suspension are displaced transversely of the tube to one or more predetermined regions; exposure of the sample to the standing wave is then terminated and the particles are allowed to settle, and inspected to determine whether they remain aggregated or whether they dissociate. The ultrasound field is produced by a transducer of tubular form encircling the tube. The invention may be used for agglutination of particles or cells via cross-bridging molecules in immuno-agglutination assays.