Abstract: An implantable metered dose drug delivery system is disclosed which comprises implantable components including an injection site, reservoir, metering valve and delivery catheter, all of which are interconnected through suitable tubing. The metering valve has a domed body constructed of a resilient elastomeric material with a fluid-flow passageway extending therethrough and opening into a chamber within the domed body. A valve is positioned within an outlet leading from the chamber, which valve is opened by exerting an external pressure on the domed body to first collapse and occlude the fluid-flow passageway and then open the valve to permit medication within the chamber to flow through the outlet. Upon release of the external pressure, the fluid-flow passageway opens and reduced pressure in the chamber draws additional fluid through the passageway to fill the chamber.

Abstract: Disclosure is made of a means and method for removing immunologically reactive compounds from the blood of living mammals. The method of the invention comprises reacting the compound with an immunological homolog of the compound, bound to the surface of a lipid vesicle and thereafter separating the resulting complex from the blood plasma of the mammal.

Abstract: An improved surgical glove, powdered to serve as a lubricant, is provided by using a polyol powder as the lubricant. The use of a polyol powder as the powdering agent for use on surgical gloves avoids the problem of starch peritonitis that has been reported upon in medical literature.In one preferred application, polyol powder is dusted onto the side of the glove that will be the glove exterior, or patient-contact surface of the glove when used. Alternatively, polyol powder is dusted onto both surfaces of the glove.

Abstract: Contraceptive device for intra uterine application in the oviducts having two enlargements 1, 2 connected by an oblong connection element 3 to a halter shape which enlargements remain fixed in the muscle tissues since the surface areas of the projections of these enlargements on a plane transverse to the longitudinal axis of the device are almost equal.

Abstract: A device for forming an orthopedic cast is disclosed which is composed of a core having a fibrous, porous tape rolled thereabout. The tape is impregnated with a first liquid component of a two-component hardenable system. The core is composed of a pressure rupturable container having the second component of the two-component system therein in liquid form. The entirety is encased in a flexible package which serves as a mixing chamber for intermixing the first and second components upon application of pressure to the package sufficient to rupture the core. After intermixing, the package is opened, the tape unrolled and placed about the broken limb in the conventional manner. The cast hardens within a short time at ambient temperature to provide a light-weight, breathable and waterproof orthopedic cast.

Abstract: A therapeutic device adapted to releasibly confine a quantity of therapeutic material therefrom to a recipient or environment of use and comprises a supporting member, means disposed in the supporting member to receive a therapeutic material, means for detecting when a predetermined amount of therapeutic material has been deposited within the receiving means and means for securing the device adjacent to the recipient or environment of use. The means for receiving the therapeutic material may comprise according to the invention a chamber, channels, or capsules. The means for detecting when a predetermined amount of therapeutic material has been deposited comprises indicia of measurement such as lines and numerals and spaced ridges or raised portions, the spaces between each of which represent a quantity of measurement. Attaching members are provided for securing the device and the therapeutic material adjacent the recipient and/or environment of use.

Abstract: A therapeutic set or kit containing a silicon rubber mixture for surgical embolization composed of(a) a linear, low viscosity polysiloxane selected from the group consisting of dialkyl, alkylaryl, alkenylalkyl, and diaryl polysiloxanes having reactive functional groups selected from the group consisting of hydroxy, acyloxy, alkoxy and amino;(b) a cyclic dialkyl polysiloxane having the formula [R.sub.2 SiO].sub.4, wherein R is alkyl; anda pharmaceutically acceptable iodo-containing organosilicium X-ray contrast material or non-metallic organic X-ray contrast material. The mixture can be used in cerebrovascular surgery and general surgery for surgical embolization with the aid of a catheter.

Abstract: A dressing which comprises an ointment impregnated open-work support, having a protector on at least one face thereof characterized in that the protector is a film soluble in water, materials therefor and the manufacture thereof are described.

Abstract: An open ended ostomy pouch having a folding bar attached to the bottom of the pouch. The folding bar extends on both sides beyond the width of the pouch at the bottom opening and includes interlocking closure components on opposite ends.