Patents Examined by Harry Guttman
  • Gravity responsive NADH oxidase of the plasma membrane
    Patent number: 6361961
    Abstract: A method and apparatus for sensing gravity using an NADH oxidase of the plasma membrane which has been found to respond to unit gravity and low centrifugal g forces. The oxidation rate of NADH supplied to the NADH oxidase is measured and translated to represent the relative gravitational force exerted on the protein. The NADH oxidase of the plasma membrane may be obtained from plant or animal sources or may be produced recombinantly.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: March 26, 2002
    Assignee: The United States of America as represented by the National Aeronautics and Space Administration
    Inventor: D. James Morre′
  • Coenzymes useful for the synthesis of L-carnitine
    Patent number: 6337197
    Abstract: The invention described herein relates to coenzymes useful for the synthesis of L-carnitine, particularly a compound of coenzyme A, and more particularly gamma-butyrobetainyl-coenzyme A and crotonobetainyl-coenzyme A, to procedures for their preparation and to their use for the production of L(−)-carnitine from crotonobetain and D(−)-carnitine.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: January 8, 2002
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Thomas Elssner, Hans-Peter Kleber