Abstract: A hydrophilic, pressure-sensitive adhesive composition comprising crosslinked poly(N-vinyl lactam), a swelling agent, and a modifying polymer in an amount sufficient to form a cohesive pressure-sensitive adhesive composition is provided. The composition is useful as a medical secural of percutaneous devices. The composition is also useful as a drug delivery device to deliver antimicrobial agents, pharmaceuticals or other active ingredients to or through skin. A method of preparation of the composition is also disclosed.
Type:
Grant
Filed:
June 5, 2003
Date of Patent:
March 8, 2016
Assignee:
3M INNOVATIVE PROPERTIES COMPANY
Inventors:
Robert A. Asmus, Beatrice C. Etzold, Joy A. Packard
Abstract: A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer.
Type:
Grant
Filed:
May 18, 2015
Date of Patent:
February 16, 2016
Assignee:
INTEC PHARMA LTD.
Inventors:
Nadav Navon, Eytan Moor, David Kirmayer, Elena Kluev, Giora Carni
Abstract: The present disclosure relates to treatment and management of Cushing's syndrome, Headache disorders and Neuropathic using a composition comprising asiaticoside and madecasosside optionally along with at least one excipient. The treatment can be extended to Myalgia and other related disease conditions.
Abstract: A novel backing construction for a transdermal drug delivery system is disclosed. In particular, the invention relates to a system and method for labeling a transdermal drug delivery system, wherein the backing layer contains a writable medium capable of inkless printing.
Abstract: An object of the present invention is to obtain a dispersion in which a water-repellent inorganic powder is dispersed in water. The dispersion can be handled easily because the dispersion medium is water. In the case of using the dispersion for cosmetics, the dispersion can be suitably used when an inorganic powder subjected to a water-repellent treatment is mixed in an aqueous cosmetic. A dispersion in which an inorganic powder subjected to a water-repellent organic surface treatment is uniformly dispersed in water, wherein the contents of a water-repellent inorganic powder, a dispersant, and water is 80% by weight or more based on the total amount of the dispersion.
Type:
Grant
Filed:
August 1, 2012
Date of Patent:
February 2, 2016
Assignee:
Sakai Chemical Industry Co., Ltd.
Inventors:
Takuro Ashida, Kunitada Nishida, Jun Iwata
Abstract: The present invention relates to acrylic emulsion polymers having excellent hair styling properties as well as their use in hair care preparations in particular hair styling preparations.
Abstract: Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from N-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions.
Type:
Grant
Filed:
August 5, 2013
Date of Patent:
January 26, 2016
Inventors:
Amal Ayoub, Nassim Safadi, Sobhi Basheer
Abstract: Mineral, cosmetic, pharmaceutical, agricultural, nutraceutical, and other compositions are produced using a mineral composition containing minimal concentrations of cadmium, lead, arsenic, and mercury and containing relatively high concentrations of micro and macro mineral elements, of rare earth elements, of calcium, and of silica. The mineral concentrations are produced by processing naturally occurring clay soil to concentrate mineral elements naturally occurring in the soil.
Abstract: An adhesive hydrogel dressing as well as to methods of applying the dressing to a patient is described. The dressing generally comprises an adhesive hydrogel pad, a backing layer, and an adhesive layer on the backing layer facing the hydrogel pad. The adhesive layer and backing layer form a perimeter around the hydrogel pad and hold the hydrogel pad in place on an application surface. The adhesive hydrogel pad is formed with at least a portion of the perimeter of the hydrogel pad tapered proximate the area that the hydrogel pad and release liner separate during liner removal.
Type:
Grant
Filed:
January 12, 2009
Date of Patent:
January 26, 2016
Assignee:
3M INNOVATIVE PROPERTIES COMPANY
Inventors:
Robert A. Asmus, David R. Holm, Daniel T. Popko, Richard L. Jacobson, Terrance M. Smorch, Donald G. Peterson, Steven B. Heinecke
Abstract: A two-step mascara product that includes a first mascara composition and a second mascara composition. The first mascara composition includes a film-forming polymer dispersed in a first carrier, and the second mascara composition includes a film-former selected from the group consisting of tall oil glycerides, pentaerythrityl rosinate, glyceryl rosinate, hydrogenated versions of these and mixtures thereof. The two-step mascara product also includes a package for storing and dispensing each of the first and second mascara compositions. The package includes a first container configured to store and dispense the first mascara composition and a second container configured to store and dispense the second composition.
Type:
Grant
Filed:
April 26, 2012
Date of Patent:
January 19, 2016
Assignee:
The Procter & Gamble Company
Inventors:
Jennifer Clare Hodgetts, Angela Michele Fabula, Thomas Elliott Rabe
Abstract: A method for controlling the attachment and growth of cells on a surface of an article, the method comprising contacting the article with living tissue, living organisms, or with water in an aqueous system comprising living organisms wherein the article comprises a substratum having a surface and a film on the surface, the film comprising a network of a net positively charged composition and a net negatively charged composition, wherein the net positively charged composition comprises a net positively charged polyelectrolyte or the net negatively charged composition comprises a net negatively charged polyelectrolyte, and the net positively charged polyelectrolyte or the net negatively charged polyelectrolyte contain (i) a polymer repeat unit having at least two fluorine atoms, or (ii) a polymer repeat unit having a zwitterion group.
Type:
Grant
Filed:
June 16, 2015
Date of Patent:
January 5, 2016
Assignee:
Florida State University Research Foundation, Inc.
Inventors:
Joseph B. Schlenoff, David S. Salloum, Thomas C. Keller, III, Scott G. Olenych
Abstract: A semi-permanent concealer composition for use on a target skin area that includes from about 10% to about 80% of a non-aqueous carrier from about 15% to about 35% of a tackifier comprising a tall oil glyceride, and from about 0.1% to about 20%, by weight, of colorant particles. The semi-permanent concealer composition is long lasting and has excellent wear characteristics.
Type:
Grant
Filed:
April 26, 2012
Date of Patent:
December 22, 2015
Assignee:
The Procter & Gamble Company
Inventors:
Thomas Elliott Rabe, James Herman Dempsey
Abstract: The present invention provides a wound healing composition comprising a biocompatible hydrogel membrane wherein the hydrogel membrane has one or more of the following properties: high water content, high transparency, high permeability, high biocompatibility, high tensile strength and an optimal thickness. The invention further provides methods of treating a wound in a subject in need thereof, comprising contacting the wound with a biocompatible cellulose hydrogel membrane of the invention.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
December 15, 2015
Assignee:
The Johns Hopkins University
Inventors:
Morgana M. Trexler, Jenna L. Graham, Jennifer L. Breidenich, Jeffrey P. Maranchi, Julia B. Patrone, Marcia W. Patchan, Jennifer H. Elisseeff, Xiomara Calderon-Colon, Daniel Mulreany, Qiongyu Guo
Abstract: The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects.
Type:
Grant
Filed:
June 26, 2015
Date of Patent:
December 1, 2015
Assignee:
The Regents of the University of California
Abstract: Provided herein are pharmaceutical formulations, comprising 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)-trans-cyclohexanol, including pharmaceutically acceptable salts, solvates, isomers, isotopologues, tautomers and racemic mixtures thereof, and a pharmaceutically acceptable excipient; and their use for treating or preventing disease.
Type:
Grant
Filed:
November 8, 2013
Date of Patent:
December 1, 2015
Assignee:
Signal Pharmaceuticals, LLC
Inventors:
Sreenivas S. Bhat, Xiaozhong Liang, Anthony Tutino, Anthony Joseph Frank
Abstract: The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects.
Type:
Grant
Filed:
June 26, 2015
Date of Patent:
November 24, 2015
Assignee:
The Regents of the University of California
Abstract: A process for preparing silicate shell microcapsules comprises adding a water reactive silicon compound to an oil in water emulsion, thereby condensing and polymerizing the water reactive silicon compound to form silicate shell microcapsules having a core comprising the oil phase of the said emulsion. The water reactive silicon compound comprises a tetraalkoxysilane and an alkoxysilane having an amino or quaternary ammonium substituted alkyl group.
Type:
Grant
Filed:
March 6, 2015
Date of Patent:
November 24, 2015
Assignee:
DOW CORNING CORPORATION
Inventors:
Thomas Bekemeier, Lorry Deklippel, Tatiana Dimitrova, Russel Elms, Fabrizio Galeone, Bertrand Lenoble, Leon Marteaux, Josef Roidl, Martin Severance, Stephane Ugazio, Brett Zimmerman
Abstract: The invention relates to a transdermal therapeutic system (TTS) which contains a rotigotine-containing adhesive layer and is characterized by the fact that the adhesive layer contains a hot-meltable contact adhesive. The invention also relates to the use of rotigotine for producing the adhesive layer of a TTS in a hot melt method, and a method for producing such a TTS.
Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.
Abstract: The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.