Patents Examined by Heidi Reese
  • Patent number: 11122997
    Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 21, 2021
    Assignees: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke University
    Inventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
  • Patent number: 11122832
    Abstract: A weight loss system is presented herein. In one embodiment, the weight loss system that accelerates weight loss in a subject eating a caloric restricted diet with a minimum daily protein intake of about 3 oz. and engaging in daily physical activity equivalent to about 5,000 steps per day is presented. The weight loss system can comprise an effective amount of: an antimicrobial component that includes berberine, cinnamon and curcumin; fish oil; a probiotic component that includes Lactobacillus spp., Bifidobacterium spp., and Streptococcus spp.; an antioxidant, phytochemical component that includes apple extract, grape extract, green tea extract, and olive extract; and a vitamin component that includes vitamins A, B, C, D, and E. The weight loss system can stimulate a weight loss of at least 3% more than if not administered to the subject. Further presented herein is a method of facilitating weight loss in a subject and a method of improving the health of a subject participating in a weight loss program.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: September 21, 2021
    Assignee: Nature's Sunshine Products, Inc.
    Inventors: Matthew L. Tripp, Clinton J. Dahlberg, John G. Babish, Joseph Lamb, Joseph J. Ou, Sarah Elison, Wei Gao, Mohan Kaadige, Holly Brabazon
  • Patent number: 11122808
    Abstract: The present invention relates to methods and compositions for illuminating, characterizing and demonstrating the uses for microbial and plant interactions, plant nutrient uptake, environmental chemical degradation, petroleum degradation, quality control for seed treatment and fertilizer blends and diagnostics on agricultural applications.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: September 21, 2021
    Assignee: NEW LIFE BIOSCIENCES, LLC
    Inventors: Marc J. Rodriguez, James S. Stansell, Joseph P. Schneider
  • Patent number: 11123324
    Abstract: The present invention provides a pharmaceutical composition to be used for the treatment or prophylaxis of allergic diseases. More specifically, the present invention provides a pharmaceutical composition to be used for the treatment or prophylaxis of allergic diseases, which contains a substance that induces selective IgA class switching in B cells. As a substance that induces selective IgA class switching in B cells, a PKC activator can be used. In addition, a composition containing a substance that induces selective IgA class switching in B cells can also be useful as a mucosal adjuvant.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 21, 2021
    Assignees: NOSTER INC., NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Reiko Shinkura, Kota Yamamoto
  • Patent number: 11123383
    Abstract: The present invention provides a composition comprising a co-culture of at least two distinct bacterial families, having differing growth and/or proliferative conditions. In some embodiments, the composition comprises a plurality of bacterial genera with high similarity to microbial flora.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: September 21, 2021
    Assignee: MYBIOTICS PHARMA LTD.
    Inventors: David Baram, David Daboush, Rachel Diamant
  • Patent number: 11116822
    Abstract: The present invention relates to a method for treating liver steatosis or non-alcoholic fatty liver by using a 2-monoacylglycerol degrading enzyme. More particularly, the present invention provides a method for treating metabolic syndrome such as liver steatosis, non-alcoholic fatty liver, hyperlipidemia, type 2 diabetes, and/or obesity by using a 2-monoacylglycerol degrading enzyme, in which the 2-monoacylglycerol degrading enzyme completely degrades triglyceride into fatty acids and glycerol in a digestive tract such that fat absorption is delayed and blood absorption of triglyceride is decreased, and in which, in a case where monoacylglycerol is degraded by a monoacylglycerol lipase in a digestive tract, although degraded products of the monoacylglycerol are absorbed into digestive epithelial cells, recombination thereof into triglyceride in the digestive epithelial cells is delayed or energy consumption is promoted during this process.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: September 14, 2021
    Assignee: INDUSTRY-ACADEMIC COOPERATON FOUNDATION, YONSE: UNIVERSITY
    Inventor: Jae Woo Kim
  • Patent number: 11116205
    Abstract: The present invention relates to reduction of erythrocyte sedimentation rate in a blood sample. In particular, formulations, compositions, articles of manufacture, kits and methods for reduced erythrocyte sedimentation rate in a blood sample are provided.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: September 14, 2021
    Assignee: BIOMATRICA, INC.
    Inventors: Joel Desharnais, Victoria Arendt, Margrith Mattmann
  • Patent number: 11118159
    Abstract: It has been discovered that the desert endophytic bacterium SA187 SA187 can provide resistance or tolerance to abiotic stress conditions to seeds or plants. Compositions containing SA187 can be used to enhance plant development and yield under environmental stress conditions.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: September 14, 2021
    Assignee: King Abdullah University of Science and Technology
    Inventors: Heribert Hirt, Axel de Zelicourt, Maged Saad
  • Patent number: 11118160
    Abstract: The present invention provides for a probiotic composition for enhancing a subject's, such as an insect's, resistance to a pesticide comprising: (a) a microorganism capable of expressing one or more enzymes for metabolizing the pesticide, and (b) at least one feed ingredient for a subject. The present invention also provides for a method for enhancing a subject's, such as an insect's, resistance to a pesticide comprising administering to a subject the probiotic composition.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: September 14, 2021
    Assignee: The Regents of the University of California
    Inventors: Kenneth H. Wan, James B. Brown, Susan E. Celniker
  • Patent number: 11099109
    Abstract: A fixative for the preservation of organic tissue and cell aggregates, comprising a hydrophilic denaturant for structural change of the molecules of the organic tissue, a lipophobic solvent, in which said denaturant is dissolved, and an amphiphilic infiltration agent which is dissolved in the solvent for dissolving fats on the surface of the biological tissue in order to accelerate a penetration of the denaturant into the biological tissue.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: August 24, 2021
    Assignee: Biosepar Gesellschaft Fur Medizin—UND Labortechnik MBH
    Inventor: Andreas Szabados
  • Patent number: 11096991
    Abstract: The present invention provides a nanoreactor (nano size reaction field) using a polyion complex polymersome and a method for producing the nanoreactor. The present invention provides a polyion complex polymersome encapsulating e.g., an enzyme, in which the enzyme is an enzyme acting on a substance passing through a membrane of the polyion complex polymersome, as a substrate.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: August 24, 2021
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Kazunori Kataoka, Yasutaka Anraku, Daiki Sueyoshi
  • Patent number: 11090342
    Abstract: A probiotic formulation is provided including one or more bacteria, bacterial strains or bacterial species of the genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, or phylum cyanobacteria.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: August 17, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: Jonathan Scheiman, George M. Church
  • Patent number: 11091783
    Abstract: A method of producing chemicals includes providing fermentative cells; co-feeding any of galacturonate and galacturonate polymers with carbohydrates to the fermentative cells; and producing a chemical from the fermentative cells. The fermentative cells may include any of Clostridium acetobutylicum and Clostridium saccharoperbutylacetonicum. The carbohydrates may include any of glucose, mannose, galactose, fructose, arabinose, xylose, sucrose, lactose, maltose, cellobiose, and starch. The method may include providing a substantially equal proportion of the any of galacturonate and galacturonate polymers and the carbohydrates for co-feeding to the fermentative cells. The method may include altering a proportion of the any of galacturonate and galacturonate polymers to the carbohydrates. The method may include modulating a production of the chemical by altering the proportion of the any of galacturonate and galacturonate polymers to the carbohydrates. The chemical may include any of acetate and butyrate.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: August 17, 2021
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Theresah N. K. Zu, Christian J. Sund, Sanchao Liu, Elliot S. Gerlach
  • Patent number: 11085928
    Abstract: A microorganism identification method includes steps of: obtaining a mass spectrum through mass spectrometry of a sample including microorganisms; reading, from the mass spectrum, a mass-to-charge ratio m/z of a peak associated with a marker protein; and identifying which bacterial species of the genus Campylobacter are included in the microorganisms in the sample based on the mass-to-charge ratio m/z. The microorganism identification method is further characterized in that at least one of the following 18 marker proteins is used as the marker protein, S10, L23, S19, L22, L16, L29, S17, L14, L24, S14, L18, L15, L36, S13, S11 (Me), L32, and L7/L12.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: August 10, 2021
    Assignees: SHIMADZU CORPORATION, MEIJO UNIVERSITY
    Inventors: Hiroto Tamura, Naomi Yamamoto, Teruyo Kato, Keisuke Shima, Shinji Funatsu
  • Patent number: 11085918
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: August 10, 2021
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmüller, Jieping Zhu
  • Patent number: 11077120
    Abstract: The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: August 3, 2021
    Assignee: Emory University
    Inventors: Thota Ganesh, Jianxiong Jiang, Raymond Dingledine
  • Patent number: 11077151
    Abstract: The present invention relates to the use of ascr #7 for preventing or treating IL-6 and/or IL-1?-mediated diseases.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 3, 2021
    Assignees: California Institute of Technology, Boyce Thompson Institute for Plant Research
    Inventors: Andrea Choe, Paul W. Sternberg, Frank C. Schroeder
  • Patent number: 11077154
    Abstract: The present invention relates to a Lactobacillus curvatus strain. In particular, the present invention relates to a composition comprising a Lactobacillus curvatus strain in combination with a further Lactobacillus and the use of the same in the treatment of inflammatory conditions in the oral cavity.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: August 3, 2021
    Assignee: Deerland Probiotics & Enzymes A/S
    Inventor: Erik Brandsborg
  • Patent number: 11076600
    Abstract: The invention relates to pesticidal mixtures of Bacillus amyloliquefaciens and cis-jasmone in synergistically effective amounts; methods of application of the pesticidal mixtures for controlling pests; and plant propagation material comprising the pesticidal mixtures.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: August 3, 2021
    Assignee: BASF SE
    Inventors: Florent Mazuir, Shaun Berry, Eda Reinot, John Hofer, Hendrik Ypema
  • Patent number: 11066692
    Abstract: Provided herein are methods for the real-time monitoring of an intracellular event or response. In particular, the methods provided herein monitor the conversion of a pro-substrate to a substrate for a protein sensor as a result of an intracellular event or response.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: July 20, 2021
    Assignee: Promega Corporation
    Inventors: James J. Cali, Sarah Duellman, Jolanta Vidugiriene, Wenhui Zhou