Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within a metal oxide shell, processes for their preparations, comparisons comprising them and uses thereof.
Abstract: The present invention provides a method for preparing a film comprising a high amount of a sildenafil free base uniformly dispersed therein and having a suitable thickness and size, as well as flexibility providing good handling stability and being not prone to breaking. The present invention also provides a sildenafil free base-containing film prepared from the method.
Type:
Grant
Filed:
February 13, 2012
Date of Patent:
March 6, 2018
Assignee:
CTC Bio, Inc.
Inventors:
Hong-Ryeol Jeon, Bong-Sang Lee, Su-Jun Park, Bong-Geun Cha, Jun-Ki Kim
Abstract: A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a subject at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period.
Abstract: The present invention relates to novel active ingredient combinations which consist of fluopyram and other known active ingredients and are very well suited for the control of animal pests, such as insects and/or unwanted acarids and/or nematodes, in foliar and soil application and/or in the treatment of seeds, and are also suitable for increasing yields.
Type:
Grant
Filed:
November 30, 2011
Date of Patent:
January 23, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Heike Hungenberg, Heiko Rieck, Robert Masters
Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
December 14, 2015
Date of Patent:
January 9, 2018
Assignee:
Galderma Laboratories, L.P.
Inventors:
Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
April 6, 2015
Date of Patent:
January 9, 2018
Assignee:
Galderma Laboratories, L.P.
Inventors:
Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-sang Liu, Matthew James Leoni
Abstract: A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a subject at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period.
Abstract: The present invention relates to a cardioplegic preparation. According to a preferred embodiment of the invention, the preparation is made of two solutions, the first containing magnesium sulfate, potassium and xylitol, and the other containing procaine.
Type:
Grant
Filed:
August 10, 2009
Date of Patent:
September 19, 2017
Assignee:
Universitat Bern
Inventors:
Erich Gygax, Thierry Carrel, Hendrik Tevaearai
Abstract: Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from Opuntia Ficus Indica cladodes in combination with other active substances are useful for the prevention or treatment of GERD (Gastro-Esophageal Reflux Disease), gastric esophagitis and related diseases (e.g. dyspepsia, esophagitis, esofageal tumour, gastro-intestinal symptoms, chronic pharyngitis, Barrett's esophagus, esophageal adenocarcinoma, GERD-related pulmonary symptoms).
Abstract: Homeopathic compositions. Implementations of topical homeopathic compositions may include an actives portion including a plurality of active ingredients and a base including a plurality of inactive ingredients where the plurality of active ingredients include tinctures and/or homeopathic preparations of Actaea spicata, Aesculus hippocastanum, Arnica montana, Atropa belladonna, Bellis perennis, Bryonia alba, Calendula officinalis, Causticum, Cimicifuga racemosa, Hypericum perforatum, Kali Carbonicum, Ledum palustre, Lithium Carbonicum, Rhododendron chrysanthum, Rhus toxicodendron, Ruta graveolens, Salicylicum Acidum, and Stellaria media and one or more tinctures and/or homeopathic preparations selected from the group consisting of Althaea officinalis, Caulophyllum thalictroides, Guaiacum, Rhamnus californica, or any combination thereof.
Abstract: A rapidly dispersing dosage form is described. The dosage form releases its active ingredients within a period of less than about ninety seconds. These dosage forms exhibit a three-dimensional shape that is retained for adequate storage but is readily dispersed in the presence of excess moisture. Also disclosed are methods of administration of a medicament and a process for the preparation of rapidly dispersing dosage forms.
Type:
Grant
Filed:
July 19, 2002
Date of Patent:
October 11, 2016
Assignee:
Massachusetts Institute of Technology
Inventors:
Jaedeok Yoo, Sandeep Kumar, Donald C. Monkhouse
Abstract: The present invention relates to compositions for pest control, more particularly insecticides, to a process for preparing them, and to the use of such formulations for sustained control of animal pests (arthropods) on various surfaces. The present invention further relates to active ingredient-wax particles in which at least one active insecticidal ingredient is dispersed in wax.
Type:
Grant
Filed:
December 19, 2011
Date of Patent:
September 27, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Volker Gutsmann, Thomas Bocker, Guenther Nentwig, Rainer Sonneck, Beate Hack, Daniel Gordon Duff
Abstract: The present invention is directed to composition for straightening or relaxing hair containing: (a) at least one hydroxide-containing active ingredient; (b) at least one polyhydric alcohol having 4 or more carbon atoms and two hydroxyl groups; (c) optionally, at least one nonionic surfactant having an HLB of from about 8 to about 20; (d) optionally, at least one amphoteric and/or zwitterionic surfactant; and (e) remainder, to 100%, of a cosmetically suitable medium.
Type:
Grant
Filed:
December 15, 2009
Date of Patent:
August 23, 2016
Assignee:
L'OREAL
Inventors:
Angela Ellington, Eric Osei-Acquah, James Cooper, Darius Danielski
Abstract: Disclosed is a topical skin care composition, and method for its use, that includes 55 to 65% by weight of water, 15 to 20% by weight of a combination of 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate (homosalate), 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione (avobenzone), 2-ethylhexyl 2-hydroxybenzoate (octisalate), and 2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate (octocrylene), 3 to 4% by weight of distearlydimonium chloride, and 1 to 3% by weight of a combination of euterpe oleracea fruit extract, punica granatum sterols, caprooyl tetrapeptide-3, tocopherol or tocopherol acetate, and niacinamide, wherein the composition has a sun protection factor of at least 15 or about 15 to 20.
Abstract: The present invention is directed to a method of using dehydroepiandrosterone to treat a human female with diminished ovarian reserve. The method includes administering about 25 milligrams three times a day of dehydroepiandrosterone per day to the female for at least four weeks to reduce human embryo aneuploidy. The present invention further is directed to a method of treating a human female with diminished ovarian reserve to improve the female's diminished ovarian reserve.
Abstract: A method for the treatment of a traumatic brain lesion comprises administering to the patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG).
Type:
Grant
Filed:
November 1, 2012
Date of Patent:
May 17, 2016
Assignee:
MAPREG
Inventors:
Etienne-Emile Baulieu, Esther Fellous, Paul Robel
Abstract: The present invention relates to methods and compositions for the treatment of neuropsychiatric conditions (e.g., bipolar disorder) by administration of prostaglandin or prostaglandin derivatives (e.g., latanoprost) to a subject (e.g., a human).
Abstract: Method of improving ovarian reserve in a human female with diminished ovarian reserve as measured by the female's anti-Müllerian hormone level. The method may include evaluating a first anti-Müllerian hormone level of the female, administering an androgen, such as dehydroepiandrosterone or testosterone, to the female for at least about one month, and then evaluating a second anti-Müllerian hormone level of the female. Change in the anti-Müllerian hormone level is indicative of change in the ovarian reserve, e.g., when the second anti-Müllerian hormone level is greater than the first anti-Müllerian hormone level, the ovarian reserve has improved. The androgen administration may continue until the second anti-Müllerian hormone level is greater than the first anti-Müllerian hormone level by a desired percentage or amount.
Type:
Grant
Filed:
June 27, 2013
Date of Patent:
December 8, 2015
Inventors:
Norbert Gleicher, David H. Barad, Dwyn V. Harben
Abstract: A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a subject at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period.