Abstract: Disclosed herein are systems and techniques for evaluating prescribed optical devices during use. A method can include matching a user profile with a prescribed optical device, matching the prescribed optical device with a plurality of members of a distribution system of the prescribed optical device, requesting information about the prescribed optical device through a user interface, receiving information in response to requesting the information, and sending feedback based on the received information to one of the members of the distribution system. One or more network devices can generate a user interface including information associated with the prescribed optical device and the user profile. The user interface can be adapted based on a primary or secondary user of the network device. The user interface can also be adapted as the user progresses in age, treatment schedule, and/or other factors that support evaluation of the prescribed optical device.

Abstract: Methods and devices include predicting future glucose and engagement levels for a user by receiving the user's glucose levels collected by a continuous glucose monitoring (CGM) device over a time period, receiving engagement data associated with the user, wherein the engagement data are associated with the user's medication intake, diet, physical activity, laboratory results, and education activity, determining a first glycemia risk index (GRI) value, determining, using a machine learning model and responsive to the user's glucose levels and the engagement data collected over the time period, one or more predictions for future glucose levels for the user including a prediction that a future GRI value is greater than or less than the first GRI value, and determining, using the machine learning model and responsive to the user's engagement data collected over the time period, one or more predictions for future engagement levels.

Abstract: The present disclosure relates generally to providing a cellular time-series imaging, modeling, and analysis platform, and more specifically to acquiring time-series image data and using various machine learning models to model and analyze subcellular particle movements and changes in cellular positional and morphological characteristics using unsupervised embedding generation. The platform can be applied to evaluate various cellular and subcellular processes by generating summary embeddings of time-series image data that enable analysis of dynamic cellular and subcellular processes over time (e.g., the movement of particles within a cell, neurites on developing neurons, etc.) for enhanced identification of differences between cell states (e.g., between sick and healthy cells) and generation of disease models which can be used to analyze the impact of various therapeutic interventions, among other improvements described throughout.

Abstract: Techniques are provided that involve employing artificial intelligence (AI) to facilitate reducing adverse outcomes associated with healthcare delivery. In one embodiment, a computer implemented method comprises monitoring live feedback received over a course of care of a patient, wherein the live feedback comprises physiological information regarding a physiological state of the patient. The method further comprises employing AI to identify, based on the live feedback information, an event or condition associated with the course of care of the patient that warrants clinical attention or a clinical response. The method further comprises generating a response, based on the identification of the event or condition, that facilitates reducing an adverse outcome of the course of care, wherein the response varies based on a type of the event or condition, and providing the response to a device associated with an entity involved with treating the patient in association with the course of care.

Abstract: Mechanisms are provided to implement a patient summary generation engine with deduplication of instances of medical concepts. The patient summary generation engine parses a patient electronic medical record (EMR) to extract a plurality of instances of a medical concept, at least two of which utilize different representations of the medical concept. The patient summary generation engine performs a similarity analysis between each of the instances of a medical concept to thereby calculate, for a plurality of combinations of instances of the medical concept, a similarity metric value. The patient summary generation engine clusters the instances of the medical concept based on the calculated similarity metric values for each combination of instances in the plurality of combinations of instances of the medical concept to thereby generate one or more clusters, and select a representative instance of the medical concept from each cluster in the one or more clusters.

Abstract: A secure, reliable telehealth delivery platform that also provides flexibility and scalability. The platform includes a plurality of geographically dispersed communication servers that facilitate communication sessions between remotely located patients and healthcare providers over a public communications network. The platform includes a connectivity server that manages access among users and locations. The platform also includes a monitoring server that monitors the health and usage of devices coupled to the network and proactively identifies issues requiring intervention before service interruptions occur.

Abstract: A method and system may provide an automated pharmacy processing system which automatically processes an electronic prescription by converting the electronic prescription into a pharmacy prescription record. In this way, an electronic prescription can be filled by a pharmacist without manual data entry. The system receives an electronic prescription and compares data from the electronic prescription with entries in one or more pharmacy database(s). When there is a match between the electronic prescription data and an entry in the one or more pharmacy database(s), the system populates the pharmacy prescription record with data from the matching pharmacy database entry. If all of the data fields from the pharmacy prescription record have been populated the pharmacist can fill the electronic prescription.

Abstract: A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.

Abstract: A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.

Abstract: A system and method for individual administration of a brain programming session including providing a device to provide visual, haptic, and audio stimuli to an individual at relevant times during the brain programming session. The system and method further include providing a list of directives configured to be executed by the individual during the brain programming session. The list of directives may reduce the individual's emotional responses to past events and conditions or to program mindsets and emotions for future performances and events. While executing the list of directives, the individual will experience visual, haptic, and audio stimuli provided by the device. Completion or partial completion of a list of directives results in brain activity being more balanced across brain regions when experiencing past events or conditions that yield an emotional response or when experiencing future performances and events for which the individual has programmed mindsets and emotions.

Abstract: The present disclosure describes an exemplary system and method for the digitization of tissue slides based on associations among serial sections. The system includes at least a computing device, wherein the computing device includes a memory and processor communicatively connected to one another, and a scanner, configured to scan a slide and send a digitized image of the slide to the computing device. A method for the digitization of tissue slides based on associations among serial sections may include receiving a candidate tissue map associated with a candidate tissue section, receiving a reference tissue map associated with a reference tissue section, aligning the candidate tissue map to the reference tissue map, comparing the aligned candidate tissue map to the reference tissue map, and generating a regenerated candidate tissue map as a function of the reference tissue map.

Abstract: The techniques described herein may provide for an evidence-based, clinical practice guideline-driven, patient communication system. A user (e.g., a patient, a client, etc.) may interact with, or use, a patient communication system for improved healthcare according to one or more aspects. The patient communication system may credibly categorize user inputs into injury patterns (e.g., correlated to healthcare industry established clinical practice guidelines). For instance, an evidence-based, clinical practice guideline-driven, patient communication system may utilize a library of extensive and credible healthcare information (e.g., reviewed by a credible body established by the healthcare industry). Such information may include physical therapy videos, recovery strategies, workplace group or client-group healthcare information, etc. The patient communication system may generate (e.g.

Abstract: Production of “regenerative medicine products” is facilitated using a quality by design (QbD) approach. A production device produces a medical product and analyzes a starting material and a central management device determines processing conditions in the production device. By transmitting and receiving data pertaining to the starting material between the production device and central management device data, the medical product is produced while production conditions therefor are continuously optimized. Thus, it is easy to produce a medical product while reducing or eliminating effects from changes in cells and tissues over time, from oscillation during transport, and from changes in surrounding environment such as changes in temperature, and to produce the desired medical product even when there are individual differences in the starting material.

Abstract: There is provided a computer implemented method for predicting a headache for a subject, comprising: feeding a plurality of physiological, behavioral, and environmental parameters obtained from a plurality of sensors monitoring the subject, into a machine learning model, and obtaining the prediction of the headache for the subject as an outcome of the machine learning model, wherein the machine learning model is trained on a training dataset of a plurality of records of a plurality of sample individuals, wherein a record includes a plurality of sample physiological, behavioral, and environmental parameters of a sample individual and a ground truth label indicative of a state of a headache of the sample individual.

Abstract: A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.

Abstract: A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.

Abstract: Novel tools and techniques are provided for implementing home health monitoring of patients via extension of healthcare system network into customer premises. In various embodiments, a computing system might receive, wirelessly from a data collector assigned to a patient, collected patient data obtained by a patient device(s) associated with the patient. The computing system and/or a management console might establish a network transport link between the computing system and a healthcare data system that is accessible by a healthcare provider(s), and might send the patient data over the network transport link to the healthcare data system. The management console might store the patient data in a portion of the healthcare data system that is allocated to information regarding the patient, wherein the network transport link is configured as a one-way link that prevents access to any data stored in the healthcare data system via the one-way link.

Abstract: A method of providing genetically personalized food recommendations includes storing, in a food micronutrient database accessible through an electronic device, a mapping of individual micronutrients to genetic information, medical information, and therapeutic objectives, a food menu for at least one restaurant, and nutrient data of each menu item on the food menu. The method also includes receiving and storing genetic information, medical information, therapeutic objectives, and dietary preferences of a user. The method also includes receiving input from the user indicating a restaurant where the user plans to eat food, identifying micronutrient(s) that match the genetic information, the medical information, and the therapeutic objectives of the user based on the mapping, identifying menu items that provide the micronutrient(s) and align with the dietary preferences of the user; and outputting to the user a personalized list of food choices at the restaurant that are healthiest for the user.

Abstract: Systems and methods for providing world-wide access to prescribed medications are provided. A prescription database receives electronic prescriptions from healthcare provider systems which are stored in one or more blockchains. Each electronic prescription is associated a unique patient identifier in the blockchain(s). Unique patient identifiers are received from pharmacy systems and the electronic prescriptions are retrieved from the patient prescription database for display. Following receipt of dispensation information from the pharmacy systems, new blocks are generated for updating the blockchain(s) at the prescription database.

Abstract: An electronic healthcare system for delivering medical services is described. The electronic healthcare systems can includes modules for accessing patient electronic medical records and ordering medical services. In response to a medical service order, a cost estimation and notification module can receive information associated with the medical service order. The cost estimation and notification module can determine the patient cost responsibility and quickly notify the patient of the costs. The patient can use the determined cost information to decide whether to move forward with the ordered medical tests.