Abstract: An ocular replacement system provides a ball-shaped implant body having an outer spherical and porous surface that is receptive to ingrowth of ocular tissue and including an anterior portion positioned forwardly when the implant is fitted in the eye cavity to create a convex tissue surface area when covered by conjunctiva. A prosthesis includes an outer face and an opposite inner concave surface shaped to conform generally to the convex tissue surface area. When fitted in the front orbital space of the eye cavity, a magnetic attractive force between at least one magnet on the inner surface of the prosthesis and one or more magnetically attractive elements on the anterior portion of the implant couples the prosthesis to the implant so that the prosthesis follows movement of the implant to simulate natural eye movement within the eye cavity.

Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis includes a self expandable wire support structure surrounded by a flexible tubular membrane. A delivery catheter and methods are also disclosed.

Abstract: A prosthetic bone material comprising a bonded and sintered product of granules of calcium phosphate compound having a particle size of at least 100 &mgr;m, each of the granules being bonded with particulates of calcium phosphate compound having a particle size of about 1 to 40 &mgr;m, in which the granules are bonded to each other while retaining their original shape, and their bonding strength is a level sufficient to maintain their own shape when the bonded and sintered product is disintegrated, produced by mixing the granules and the particulates, followed by firing the mixture at a temperature of about 800 to 1,200° C.

Abstract: An easy-to-produce and mechanically strong tube of an implantable submucosal tissue has been developed which is manufactured in any desired length, wall thickness, or diameter. The construct produced by the method of the invention may be used as grafts for arteries, veins, ureters, urethras, shunts, or in any application where a compliant, tissue-compatible tube is needed. The manufacture of the submucosal tissue prosthesis generally involves wrapping a first sheet of submucosal tissue (60) and a second sheet of submucosal tissue (70) around a mandrel (50), wherein the first end (74) and the second opposite end (76) of the second sheet of submucosal tissue (70) are sutured together with sutures (78). The submucosal tissue is compressed and dried on the mandrel (50) before removing the construct by pulling on a first end (54) and a second end (56) of a water permeable tape to unwind the tape and thus release the construct for eventual use.

Abstract: Femoral component for a knee prosthesis adapted to cooperate with an insert attached to a tibial plateau anchored at the upper end of a tibia. The femoral component is adapted to be anchored at a lower end of a femur, the femoral component including a first lateral condyle, a second lateral condyle, and an intercondylar space disposed between the first and second condyles for receiving a third removably fixed condyle. The third condyle is removable from the intercondyle space while the femoral component remains moveably engaged with the tibial plateau. The third condyle is adapted to provide posterior stabilization of the prosthesis during flexion between the tibia and the femur when the posterior cruciate ligament is no longer able to substantially perform its function.

Abstract: A radially-expandable stent for insertion into a lumen is described. The stent is composed of a radially-expandable support stent and a polymer tubular member co-axially disposed over the support stent. Tubular end sleeves are disposed around the first and second ends of the polymer-surrounded support stent to secure the tubular member and to provide other improvements.

Abstract: A spinal disc prosthesis to replace a damaged spinal disc in a spinal column of a human includes an upper rigid plate having an outer perimeter and a lower rigid plate having an outer perimeter. A body of elastomeric material located between and bonded to the upper and lower rigid plates includes a main portion and a peripheral portion extending around the main portion. The upper and lower plates each have a curved convex plate surface extending around the respective outer perimeters and facing the peripheral portion of the body of elastomeric material. The peripheral portion of the body of elastomeric material has a first part which is bonded to the curved convex plate surfaces of the upper and lower plates and extends toward the main portion. The first part of the peripheral portion increases in thickness as the first part extends from the curved convex plate surfaces toward the main portion.

Abstract: A combined stent/graft structure for repair of a body tube in a living body. The structure includes a textile graft adapted to enhance fluid integrity of the body tube and a stent expandable between a first position permitting easy insertion of the stent into the body tube and a second position wherein the stent presses securely against the inside surface of the body tube. The stent includes a first elongate wire-shaped stent member with both a stent member global axis and a stent member local axis, and is integrally secured to the graft by at least one graft yarn of which the graft is formed. Substantial portions of the first stent member global axis form a non-orthogonal angle with the graft main portion axis when projected into a plane containing the graft main portion axis. A woven textile is also part of the invention as is a method of manufacturing such a woven textile, which can be used to produce stent/graft structures according to the invention.

Abstract: A braided self-expandable stent-graft-membrane made of elongated members forming a generally tubular body. A membrane layer and graft layer are disposed on a endoprosthesis such as a stent. The membrane layer is substantially impermeable to fluids. The outermost layer is biocompatible with the body tissue. The innermost layer is biocompatible with the fluid in the passage. An embodiment includes a graft layer disposed on the inside of a stent and a membrane layer disposed on the outside of the stent. The innermost layer is biocompatible with the fluid in the passage. The stent-graft-membrane is used at a treatment site in a body vessel or organ where it is desirous to exclude a first fluid located outside the endoprosthesis from reaching a second fluid located in the lumen. The membrane may be made of silicone or polycarbonate urethane. The graft may be braided, woven, spun or spray-cast PET, PCU, or PU fibers. The layers may include ePTFE or PTFE.

Abstract: A stent assembly includes a balloon and an expandable stent positioned at an exterior of the balloon. The stent includes a first expansion strut. A plurality of the first expansion struts form a first expansion column. A plurality of second expansion struts form a second expansion column. A plurality of the first connecting struts form a first connecting strut column. Each of a first expansion strut of the first expansion column is coupled to a second expansion strut of the second expansion column. The first connecting strut includes a proximal section coupled to a distal section and at least a portion of the first connecting strut includes a first linear section and a first slant angle.

Abstract: A luminal endoprosthesis for ramification of anatomical conduits in mammals, especially humans, and to a method for manufacturing this endoprosthesis.The latter includes at least one radially compressible and extendable tubular structure and includes at least one base element 12 with a continuous multifilament structure delimiting a longitudinal cavity 14 open at its two ends 16, 18.This at least one base element 12 includes two flexible segments 20, 22 extending one in a continuation of the other, substantially along the same axis in the absence of stress, and at least one lumen 24 opening into the cavity 14.

Abstract: A process for preparing porous bioceramic materials includes the following steps: (a) using the cancellous bone of animals, (b) removing organic substances in the cancellous bone by thermal processing to obtain de-organic cancellous bone, (c) soaking the de-organic cancellous bone in a solution of phosphate salts, and (d) obtaining porous bioceramic materials by sintering up to 900.degree. C. or higher after dehydration. The porous bioceramic materials of the present invention are suitable for use as filling materials for bone defect.

Abstract: A device and method for loading a self expanding stent into a deployment tool is disclosed. The device includes an outer tube and a constricting sheath having a stent delivery end and a stent receiving opening opposite thereto. The stent receiving opening is shaped and sized to receive a self expanding stent aligned along the axis and in its expanded state. A funnel, positioned within the constricting sheath, is shaped for collapsing the self expanding stent before loading the stent into the space of the outer tube. An inserter is used to engage and urge the expanded stent into the constricting sheath as the inserter moves towards and into the funnel of the constricting sheath.

Abstract: An endovascular graft having at least two barrier sections coupled to form a substantially tubular member. The barrier sections are coupled or connected to each other so as to allow relative axial displacement of the sections. The axial displacement of the barrier sections of the graft allows for a reduced profile and increased flexibility during delivery of the device to a desired site for deployment. The device may be delivered percutaneously or intraoperatively.

Abstract: A femur endoprosthesis for an artificial hip joint is provided with a stem (1) which can be implanted without cement in the upper region of a femur below the greater trochanter. The proximal end (8) of the stem is connectable with an adapter (2) for accommodating an artificial spherical part of a joint (20). The exterior of the stem is at least partially covered with an open-meshed three-dimensional spatial lattice structure (9). A distal end of the stem is bent caudally with a caudally oriented step (31) in the transition area and constructed as a stem end (30), which is also at least partially covered with an open-meshed three-dimensional spatial lattice structure (9).

Abstract: A welding method for improving the durability and strength of fusion weld joints in metal structures; the method is especially beneficial for metal structures fabricated from nickel-titanium alloy (nitinol) and for medical devices.

Abstract: The present invention provides an epoxy compound that has a hydrocarbon backbone, that is water-soluble, and which does not contain an ether or ester linkage in its backbone. Examples of suitable epoxide agents include mono- or diepoxides that have the following basic formulas: ##STR1## where n=1 to 10.

Abstract: Prosthetic implants designed to be implanted in the cornea for modifying the cornea curvature and altering the corneal refractive power for correcting myopia, hyperopia, astigmatism, and presbyopia, and, in addition, such implants formed of a micro-porous hydrogel material.

Abstract: Tubular stents are formed from a sheet of material having longitudinally extending margins and an expandable pattern between the margins. The sheet can be formed to a tube with the margins overlapped and secured. The margins may be provided with means to facilitate registration of the margins.

Abstract: A tissue graft composition comprising stomach submucosal tissue delaminated from both the luminal portion of the tunica mucosa and the smooth muscle layers of the muscularis externa of a stomach of a warm blooded vertebrate is described. The graft composition can be or implanted into a host to replace or support damaged or diseased tissues.