Patents Examined by Holly M Mull
  • Patent number: 10611991
    Abstract: A pulsatile perfusion bioreactor for culturing one or more engineered blood vessels having a lumen and a wall is provided. The bioreactor includes a chamber for holding the engineered blood vessel and cell culture media; a mechanical property monitoring system for measuring axial tensile stress and strain, circumferential tensile stress and strain, and/or shear stress imparted on the vessel wall; and a pump system for delivering cell culture media through the vessel lumen, wherein the vessel is exposed to a composite pressure waveform and a composite flow waveform as the media is delivered there through. The pump system includes a steady flow and peristaltic pumps. Further, the composite pressure and flow waveforms each include a mean component, a fundamental frequency component, and a second harmonic frequency component. The bioreactor also includes a computer interface for monitoring and adjusting the composite waveforms to maintain a predetermined stress levels.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: April 7, 2020
    Assignee: University of South Carolina
    Inventors: John F. Eberth, Tarek Shazly, Boran Zhou, David A. Prim, Conrad Michael Gore
  • Patent number: 10588991
    Abstract: A disinfectant device including a pouch, the pouch including a first layer of material coupled to a second layer of material and defining a compartment therebetween. At least one dry reactant is retained within the compartment, the at least one dry reactant producing chlorine dioxide gas when exposed to water. A wick is at least partially disposed within the compartment. At least one from the group consisting of the first layer of material and the second layer of material define an array of ports along a periphery of the pouch and an array of fluid conduits, the array of fluid conduits being proximal to the array of ports, offset from the array of ports, in fluid communication with the wick, the compartment, and the array of ports.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: March 17, 2020
    Assignee: Odorstar Technology, LLC
    Inventor: Peter Dornau
  • Patent number: 10557111
    Abstract: The object of the present invention is to provide a cell culture vessel having a plurality of microwells, which allows to identify the position of a microwell by observing it under a microscope without moving a viewing position, which has identifiers to be easily disposed to the microwells. The present invention is directed to a cell culture vessel comprising a bottom and a sidewall, in which the bottom has a cell containing section in which a plurality of microwells for containing cells are disposed, identifiers are disposed in the vicinities of the plurality of microwells so as to make pairs in individual microwells, and the relative position of each of the identifiers to a partner microwell varies in every pair.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: February 11, 2020
    Assignee: DAI NIPPON PRINTING CO., LTD.
    Inventors: Tomonori Akai, Masanori Kagota, Takuma Baba
  • Patent number: 10550361
    Abstract: A biogas plant is provided comprising a fermentation container for receiving fermentation material to be fermented. The fermentation container comprises a lower wall part and an upper wall part where the upper wall part is positioned above the lower wall part. Further, the biogas plant comprises a support and a hinge wherein the hinge hingedly connects the fermentation container to the support and wherein the hinge defines a pivot axis about which the upper wall part and the lower wall part are pivotable.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: February 4, 2020
    Assignee: THÖNI INDUSTRIEBETRIEBE GMBH
    Inventor: Thomas Köll
  • Patent number: 10548999
    Abstract: A preform is easily and speedily sterilized. A number of preforms (1), each having a bottomed tubular shape, are laid on a conveyer (4) in a scraggly overturned manner, these preforms passes inside a chamber (5) together with the conveyer, and hydrogen peroxide water mist is sprayed from both sides of the conveyer in a direction crossing the conveyer in the chamber, thereby adhering the sprayed hydrogen peroxide water to inner and outer surfaces of the preforms (1) on the conveyer (4).
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 4, 2020
    Assignee: Sai Nippon Printing Co., Ltd.
    Inventors: Yoshihiro Miyahara, Hirotaka Tsuchiya, Yoshio Nishida
  • Patent number: 10550382
    Abstract: Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled acoustic standing wave results in an acoustic radiation force having an axial force component that deflects the materials, so that the materials and the host fluid can thus be separated. The angled acoustic standing wave can be oriented at an angle of about 20° to about 70° relative to the direction of mean flow through the flow chamber to deflect, collect, differentiate, or fractionate the materials from the fluid flowing through the device at flow rates of about 400 mL/min up to about 700 mL/min.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: February 4, 2020
    Assignee: FloDesign Sonics, Inc.
    Inventors: Bart Lipkens, Walter M. Presz, Jr., Kedar Chitale, Thomas J. Kennedy, III, Ben Ross-Johnsrud
  • Patent number: 10524648
    Abstract: A reprocessing system includes a decontamination basin, a lid, a cleaning assembly, an exterior body, and an actuating panel assembly. The lid is configured to enclose the interior surface of the decontamination basin in a closed configuration. The lid and an interior surface of the decontamination basin are configured to cooperate to house a medical device when in the lid is in the closed configuration. The cleaning assembly is operable to clean a medical device housed in the decontamination basin. The actuating panel assembly is configured to transition between a withdrawn position and an extended position. The actuating panel assembly is configured to be enclosed by the lid and the interior surface of the decontamination basin in the withdrawn position. The actuating panel assembly is configured to extend above a portion of the exterior body while the actuating panel assembly is in the extended position.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: January 7, 2020
    Assignee: ASP GLOBAL MANUFACTURING GMBH
    Inventor: Nick N. Nguyen
  • Patent number: 10517977
    Abstract: A device and method for decontaminating the interior of a biosafety cabinet using a drug considered to be safe for humans is provided. A device for decontaminating the interior of a biosafety cabinet includes an ultrasonic atomizer for atomizing a peracetic acid disinfectant using ultrasound and releasing droplets; a diffusion fan; a circulation fan; a temperature-humidity sensor; and a controller.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: December 31, 2019
    Assignee: NITTA CORPORATION
    Inventor: Akio Sakaki
  • Patent number: 10513468
    Abstract: The disclosure relates to a composting device including a housing defining an interior with an access opening providing access to the interior, a composter bin located within the interior and in communication with the access opening, and a user operated door slidably mounted to the housing and electrically powered to automatically slide along a sliding path between opened and closed position.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: December 24, 2019
    Assignee: Whirlpool Corporation
    Inventor: Abhishek P. Buzruk
  • Patent number: 10501718
    Abstract: Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: December 10, 2019
    Assignee: OLYMPUS CORPORATION
    Inventors: Akira Matsushita, Shintaro Takahashi, Masaru Mizunaka, Shinichi Takimoto, Tadashi Hirata, Yohei Tanikawa
  • Patent number: 10500294
    Abstract: Devices, methods and systems of disinfecting medical instruments, more particularly blood glucose meters. A disinfection cradle including a flat base for positioning the cradle on a surface, the cradle having a receptacle configured to receive the diagnostic apparatus, and a UV source positioned in the receptacle that is configured to administer a disinfection cycle to the diagnostic apparatus by directing UV light outward at the diagnostic apparatus received in the receptacle, the UV light being able to act as a disinfecting agent to the disinfection cradle and diagnostic apparatus.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: December 10, 2019
    Assignee: Trividia Health, Inc.
    Inventors: Patrick J. Paul, Edward David Arguello, Brent E. Modzelewski
  • Patent number: 10487303
    Abstract: The invention discloses an automatic off-line gas-water combined-washing membrane bioreactor, comprising a PLC automation control cabinet, a MBR reactor, a MBR membrane assembly, a rotating hood, an annular guide rail, a lifting device, a washing pipe network, an external interface, a gas washing pipe, a water washing pipe, a gas pump and a water pump, wherein the gas pump, the water pump and the three-way change valve are all connected with the PLC automation control cabinet, the washing pipe network is provided with several nozzles. The present invention adopts a full PLC automation control system, the PLC automation control cabinet controls a pressure washing pump (gas pump and water pump), and gas or water is injected into the washing pipe network by flexibly adjusting the three-way change valve, so that the operation is simple, the cleaning is complete, and the manual operation load is reduced.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: November 26, 2019
    Assignee: Guangzhou Guangshen Environmental Sci-Tech Co., Ltd.
    Inventors: Xinyi Chen, Shanglong Wen, Jianyun Shi, Yanfang Zhang, Haochun Zhang
  • Patent number: 10481075
    Abstract: A microorganism evaluation system comprising a viewing section for image acquisition, the viewing section comprising a viewing port configured to accommodate a fluid flow, at least one independently controlled imaging light source operably installed in the viewing section and configured to selectively illuminate the viewing port, and at least one independently controlled light stimulation device operably installed in the viewing section and configured to selectively emit light for invoking a motile response in a microorganism within the fluid flow in the viewing port, whereby the system synchronizes illumination of the at least one imaging light source and the at least one light stimulation device of the viewing section.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: November 19, 2019
    Assignee: SoBru Solutions, Inc.
    Inventor: John Miles Brubacher
  • Patent number: 10465156
    Abstract: A cap for cell culture container enclosing a culture volume and having an opening, comprising a valve arrangement, suitable for filling of the cell culture container with a fluid and/or for pumping fluid out from the cell culture container, and a compensation opening suitable for aerating the cell culture container and/or for pressure compensation during filling and pumping out, said valve arrangement being designed to be switchable between an outlet position and a blocking position, to be connectable to a fluid supply interface, and to be switchable without contact.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: November 5, 2019
    Assignee: Hamilton Bonaduz AG
    Inventors: Thomas Jaeger, Carsten Etzold, Rene Demarmels
  • Patent number: 10457962
    Abstract: Improved methods for anaerobic digestion of organic matter to produce biogas. Among the improvements given are including ferric iron in a hydrolysis reactor to increase the rate and efficiency of anaerobic hydrolysis to provide substrates for methanogenesis. A solids separation step is added after hydrolysis and before methanogenesis to improve the efficiency of the methanogenesis step. Other improvements involve using separate tanks for the hydrolysis and methanogenesis stages and using two (or more) methanogenesis tanks in sequence, and switching the order of the two (or more) methanogenesis tanks periodically.
    Type: Grant
    Filed: October 30, 2016
    Date of Patent: October 29, 2019
    Assignee: Virerco AD, LLC
    Inventors: Surya Raja Pidaparti, Jeffrey Ray Zierdt, Joseph Philip Burke
  • Patent number: 10443028
    Abstract: Techniques for providing in vivo environments to in vitro cells by periodically applying mechanical stimuli to in vitro cells are provided for effective studies on cell culture.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: October 15, 2019
    Assignee: CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Seung Hwan Chang, Ji Hun Bae
  • Patent number: 10434203
    Abstract: Methods of reducing the incidence of healthcare-associated infections in various healthcare settings are provided. Methods for preventing or reducing the number of infections in a human or animal population are also provided. The methods as provided herein reduce the presence of various infectious agents that are commonly acquired or transmitted and are present on both animate and inanimate surfaces, including those infectious agents commonly found in healthcare settings. By reducing the presence of such infectious agents, the incidence of various types of infection or disease is thereby reduced.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: October 8, 2019
    Assignee: WELL Shield LLC
    Inventors: Stewart Benson Averett, Devron R. Averett
  • Patent number: 10407658
    Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: September 10, 2019
    Assignee: Berkeley Lights, Inc.
    Inventors: Russell A. Newstrom, Andrew W. McFarland, Darcy K. Kelly-Greene, J. Tanner Nevill, Gang F. Wang
  • Patent number: 10399110
    Abstract: A rust inhibition system in which a rust inhibitor liquid is applied to a wand, which is then inserted into a cavity. The wand serves as a reservoir to provide the inhibitor liquid in areas susceptible to corrosion. A sleeve can be included to cause the inhibitor liquid to secrete from the wand.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 3, 2019
    Inventor: Rodney Good
  • Patent number: 10398798
    Abstract: Technologies are generally described for devices and methods effective to disperse fragrance from a material. A first portion of a housing of an air freshener device may be detached from a second portion of the housing. A ring-shaped scented material may be installed into an enclosure formed between the first portion of the housing and the second portion of the housing. The first portion of the housing may be fastened to the second portion of the housing. A fan may be powered to cause the fan to rotate around an axis. A fragrance of the scented material may be dispersed with air blown from the fan. The first portion and the second portion of the housing may be centered around the axis when the first portion of the housing is fastened to the second portion of the housing.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: September 3, 2019
    Assignee: Alfred Esses
    Inventor: Alfred Esses