Patents Examined by Howie Matthews
  • Patent number: 10327885
    Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: June 25, 2019
    Assignees: The General Hospital Corporation, The Charles Stark Draper Laboratory
    Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
  • Patent number: 10226560
    Abstract: Disclosed is an electromechanical device generating bilateral pressure impulses, wherein the alternative and specular movement of the homologous cursors (CV, CO), pacing one of the Cartesian axes, exclusively manages mobile cores (NEM) of electromagnets (EM) with planned solicitation, for supplying the necessary mechanical energy for the correct working of operating machines of different kinds, and in particular of a permanent artificial heart.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: March 12, 2019
    Inventor: Ubaldo Lanucara
  • Patent number: 10219945
    Abstract: A fiducial is generated on an internal anatomical structure of the eye of a patient with a surgical laser. A tonic artificial intraocular lens (IOL) is positioned so that a marker of the tonic IOL is in a predetermined positional relationship relative to the fiducial. This positioning aligns the tonic IOL with the astigmatic or other axis of the eye. The toric IOL is then implanted in the eye of the patient with high accuracy.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: March 5, 2019
    Assignee: Optimedica Corporation
    Inventors: David D. Scott, David Dewey, Javier Gonzalez
  • Patent number: 10201358
    Abstract: Aligning the syndesmosis joint by a novel device and method includes establishing a first plane by attaching a bone plate to the posterolateral aspect of the distal fibula. A second transverse plane arranges perpendicular to the first nominal plane. A syndesmosis targeting guide device includes a post having a post axis extending perpendicular to the first plane and in the second plane. The device includes a curvilinear slider guide extending along an arc in the second plane. The slider is positioned to a first position and fixing that first position to establish a fixed entry point in the fibula wherein the fixed entry point lies in the second plane and further thereby establishing a desired trajectory in the second plane wherein the trajectory includes the fixed entry point based on the slider first position.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: February 12, 2019
    Assignee: Acumed LLC
    Inventors: Andrew W. Seykora, James W. Michelinie
  • Patent number: 10166096
    Abstract: Accommodating intraocular (AIOL) assemblies for enabling post implantation in situ manual selective displacement of an AIOL along a human eye's visual axis relative to stationary anchor points. Axial displacement may be over a continuous range or alternatively at discrete axial stopping positions typically from about 100 ?m to about 300 ?m apart. Novels AIOLs designed to be at least partially folded for facilitating insertion into a human eye through a relatively small incision.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: January 1, 2019
    Assignee: ForSight Vision6, Inc.
    Inventor: Joshua Ben Nun
  • Patent number: 10166102
    Abstract: A tissue shaping device adapted to be disposed in a vessel near a patient's heart to reshape the patient's heart. The device comprises a first anchor and a second anchor adapted to be deployed by a catheter to engage a vessel wall while the first anchor is adapted to resist the compression of a first part of the first anchor and resist the expansion of a second part of the first anchor in response to a compressive force on the first part.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: January 1, 2019
    Assignee: Cardiac Dimensions Pty. Ltd.
    Inventors: Gregory D. Nieminen, Carly A. Thaler
  • Patent number: 10159565
    Abstract: An intraocular lens, and a system and method of customizing at least one characteristic for an intraocular lens, in accordance with a regression that indicates the postoperative spherical aberration at the iris plane of a patient aphakic eye, in order to obtain a desired postoperative condition. The lens, system and method of customizing at least one characteristic of an intraocular lens may include measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration and an anterior chamber depth of the eye, and empirically calculating a spherical aberration at an iris or pupil plane of the eye, based on a regression formula comprising at least the corneal spherical aberration and the anterior chamber depth, and cross products thereof.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: December 25, 2018
    Assignee: AMO Groningen B.V.
    Inventors: Marrie H Van Der Mooren, Patricia Ann Piers, Theophilus Bogaert, Sverker Norrby, Carmen Canovas-Vidal
  • Patent number: 10149976
    Abstract: A method for implanting a wireless neural stimulator device, the method including: making a surgical incision or a percutaneous opening on a patient's skin; inserting an assembly of an introducer or needle and a needle stylet through the surgical incision or a percutaneous opening and underneath the patient's skin, the needle stylet mounted in an inner lumen of the introducer or needle; withdrawing the needle stylet from the inner lumen of the introducer or needle when the assembly is in place; inserting the wireless neural stimulator device through an inner lumen of the introducer or needle and into the patient's tissue; and withdrawing the introducer from the surgical incision or percutaneous opening.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: December 11, 2018
    Assignee: Micron Devices LLC
    Inventors: Chad David Andresen, Laura Tyler Perryman
  • Patent number: 10143530
    Abstract: According to embodiments, a membrane with a flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting corneal endothelial cells, to cover the anterior and posterior surface of the iris, or to cover the surface of the posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer material. In particular, the membrane has high transparency and high water retention in a wet state.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 4, 2018
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Yu-Bing Liou, Hsiu-Ying Wang, Hsin-Yi Hsu, Wei-Li Chen, Chin-Tsung Huang, Hsin-Hsin Shen
  • Patent number: 10143548
    Abstract: Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing a piggyback lens which in combination with the cornea and an existing lens in the patient's eye redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The piggyback lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the piggyback lens can be configured to improve or reduce optical errors at the location on the peripheral retina.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: December 4, 2018
    Assignee: AMO Groningen B.V.
    Inventors: Robert Rosen, Hendrik A. Weeber, Carmen Canovas Vidal, Marrie Van Der Mooren, Dora Sellitri, Patricia Ann Piers
  • Patent number: 10143586
    Abstract: A treatment method is provided that includes an introduction step of introducing a transparent stent into a vitreous body of an eyeball, an expansion step of causing the stent to expansively deform inside the vitreous body to bring a retina into contact with a retinal pigment epithelium, and a placement step of placing the stent in the vitreous body with the stent keeping the retina in contact with the retinal pigment epithelium.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: December 4, 2018
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Naoko Maruyama
  • Patent number: 10136805
    Abstract: An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: November 27, 2018
    Assignee: AMO Groningen B.V.
    Inventors: Carmen Canovas Vidal, Pablo Artal
  • Patent number: 10136895
    Abstract: The invention provides methods for reducing the incidence and/or severity and/or delaying the onset of heart dysfunction/failure and improving overall survival through the use of remote ischemic per-conditioning and post-conditioning.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: November 27, 2018
    Assignee: The Hospital for Sick Children
    Inventor: Andrew Redington
  • Patent number: 10136990
    Abstract: Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing a piggyback lens which in combination with the cornea and an existing lens in the patient's eye redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The piggyback lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the piggyback lens can be configured to improve or reduce peripheral errors at the location on the peripheral retina.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: November 27, 2018
    Assignee: AMO Groningen B.V.
    Inventors: Robert Rosen, Hendrik A. Weeber, Carmen Canovas Vidal, Marrie Van Der Mooren, Dora Sellitri, Patricia Ann Piers
  • Patent number: 10137014
    Abstract: A stent (32) configured to be placed in a body lumen and having a tubular shape formed by a structure that is expandable and contractible skeleton (18, 19) in a radial direction, the skeleton (18, 19) having a heteromorphic structure due to changes of a cross section shape thereof in a thickness direction. A stent (10) that is expandable and contractible in the radial direction while being configured to be placed in a body lumen, the stent (10) having a heteromorphic tubular shape, a cross section shape of which changes in a lengthwise direction, and having a metal skeleton (18, 19) formed by at least one of electroforming and etching.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: November 27, 2018
    Assignee: NIPRO Corporation
    Inventors: Yoshihiko Sano, Yasushi Ooyama, Katsuhiro Hiejima, Kouji Akimoto
  • Patent number: 10123869
    Abstract: The present invention relates generally to the restoration or improvement of the quality of human vision and, more particularly to a self-adapting system and method for achieving automatic sharp vision by the human eye of objects for instance at distances between 25 cm and more than 10 meters away. The invention can be situated in at least four technological domains: 1. ophthalmology, in particular the implantation of intraocular lenses. 2. Non-contact biometric signal recording and processing. 3. Electro-optic control of refractive lens power. 4. Wireless energy transfer.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: November 13, 2018
    Assignee: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Johan Blanckaert, Christ Glorieux, Robert Puers
  • Patent number: 10111746
    Abstract: A prosthetic capsular device configured to be inserted in an eye after removal of a lens, in some embodiments, can comprise a housing structure comprising capable of containing an intraocular device and an equiconvex refractive surface. The housing structure can comprise an anterior portion comprising an anterior opening, a posterior portion comprising a posterior opening, and a continuous lateral portion between the anterior portion and the posterior portion.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: October 30, 2018
    Assignee: Omega Ophthalmics LLC
    Inventors: Gary N. Wortz, Rick William Ifland
  • Patent number: 10105215
    Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The optic is disposed about an optical axis and includes an anterior surface and a posterior surface defining a clear aperture of the optic. The haptic is at least partially disposed inside the optic and includes an inner structure, an outer structure, and a plurality of arms disposed between and connecting the inner structure and the outer structure. The inner structure is circumferentially disposed about the optical axis, while the outer structure is circumferentially disposed about the inner structure and has an outer face. Each arm has proximal portion adjacent the inner structure and a distal portion adjacent the outer structure that is bifurcated in a radial direction from the proximal portion. The intraocular lens also has an outer surface defined by outer surfaces of the plurality of arms and an outer surface of the outer structure.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: October 23, 2018
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventor: Timothy R. Bumbalough
  • Patent number: 10098727
    Abstract: An intraocular adaptive lens prosthesis apparatus is provided. In some implementations the apparatus includes a tunable liquid crystal lens encapsulated in the intraocular prosthesis with control electronics and a power source. In other implementations the apparatus includes a tunable liquid crystal lens encapsulated in the intraocular prosthesis with a control signal receiver while an external control electronics package transmits the control signal. The tunable liquid crystal lens is driven in response to a stimulus signal to provide accommodation. In some embodiments the tunable liquid crystal device corrects other visual shortcomings of the natural eye.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: October 16, 2018
    Assignee: LensVector Inc.
    Inventor: Tigran Galstian
  • Patent number: 10092772
    Abstract: A system and methodology for treating patients with dementia using a methodology which includes a functional assessment of the patient to determine the patient's cognitive and daily living capabilities that is used to prepare a functional assessment of the patient to determine the patient's cognitive and daily living capabilities. The treatment uses a plurality of rooms providing living quarters the patients, with a control system executing a lighting program for a lighting system that is configured to simulate a plurality of different phases of daylight over a period of time. Furthermore, the lighting system includes a structure for adapted for simulating clouds. Also, the system provides at least one room having the lighting system and providing plants and flowing water providing an illusion of the room being outdoors.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 9, 2018
    Assignee: Orcus Systems and Solutions, Inc.
    Inventor: Nesian Jean Makesh