Abstract: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula I
wherein the substituents are as defined in claim 1, are described.
These compounds inhibit the tyrosine kinase activity of the receptor for epidermal growth factor (EGF) and c-erbB2 kinase and can be used as anti-tumor agents.
Type:
Grant
Filed:
April 1, 1999
Date of Patent:
June 26, 2001
Assignee:
Novartis AG
Inventors:
Guido Bold, Jörg Frei, Marc Lang, Peter Traxler
Abstract: Infrared radiation-sensitive compounds have been found that are represented by Structure DYE as follows:
wherein R is a secondary or tertiary amine that contains no heterocyclic group, R1 and R2 are independently carbocyclic aromatic groups, and M+ is a monovalent cation. These compounds have a &lgr;max above 700 nm and are can be used in a number of photosensitive or heat-sensitive imaging materials.
Type:
Grant
Filed:
June 8, 2000
Date of Patent:
June 19, 2001
Assignee:
Eastman Kodak Company
Inventors:
Kevin W. Williams, Shiying Zheng, Thap DoMinh