Abstract: The present invention relates to a medicament delivery device. The medicament delivery device may include an operation member configured to act on a medicament container for expelling a medicament. The device may configured to hold the operation member in a pre-tensioned state. The device may include an activation member configured to interact with the operation member to release it from the pre-tensioned state. The device may further comprise feedback. For example, the feedback may include generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: A syringe barrel including a tubular, barrel body operable to receive a syringe plunger at a proximal end thereof and a syringe needle at a distal end and sidewalls of said syringe body being flexible and elliptical in cross-section and opposing compression of said syringe barrel at opposite ends a major axis of said syringe barrel cross-section serving to operably flex the elliptical cross-section of said syringe body into a more circular cross-sectional configuration and increasing the volume of said syringe barrel body and concomitantly serving to create a relative vacuum within said syringe body as compared with the configuration of said syringe tubular, barrel body prior to application of said compression.

Abstract: Balloon catheters that include a balloon and an elastomeric sheath, each having a surface with a therapeutic agent disposed thereon, along with methods of making and methods of using the disclosed balloon catheters.

Abstract: The present disclosure provides a bipolar forceps. The bipolar forceps includes a housing having a handle assembly including a movable handle and one or more shafts. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. A solenoid is in operative communication with the movable handle and operatively couples to a drive rod operatively coupled to at least one of the first and second jaw members for causing movement thereof. One or both of the first and second jaw members includes one or more teeth configured to engage one or more teeth located on the drive rod such that rotation of the solenoid imparts one of longitudinal and rotational movement of the drive rod such that at least one of the first and second jaw members moves between the open and closed positions.

Abstract: The invention relates to systems and methods for controlling vacuum within phacoemulsification systems. The phacoemulsification system may include a handpiece having a needle coupled to a power Source configured to cause the needle to be ultrasonically vibrated during operation, and an aspiration Source. The system includes a footpedal that defines a first position and a second position, and also includes a computer program product operatively coupled to the handpiece and the foot pedal, having a computer usable medium with a sequence of instructions which causes the processor to control power from the power source and vacuum from the aspiration source applied to the handpiece. The process provides a vacuum at a first level to the handpiece when the footpedal is at the first position; provides power to the handpiece when the footpedal is at the second position; and reduces the vacuum to a second level when the footpedal position transitions.

Abstract: Systems and methods for delivering microneedles to a patient's skin are described. In one aspect, a system for delivering a microneedle array to a patient's skin surface is provided. The system includes a delivery apparatus with a housing, and an infusion device detachably received in the housing.

Abstract: An automated peritoneal dialysis therapy device includes pump tubing for delivering dialysate to a patient and for removing waste from the patient; a retractable peristaltic pump assembly; and a processor for controlling operations of the automated peritoneal dialysis therapy device. The retractable peristaltic pump assembly includes a retractable peristaltic pump having a pump rotor and a pump base, a heating source, located in the pump base, to heat the dialysate, a first temperature sensor to measure a temperature of the heating source, a second temperature sensor to measure a temperature of the dialysate, a flow sensor to measure an amount of dialysate being pumped, a pressure sensor to measure a pressure of the dialysate being pumped, and a motor to rotate the pump rotor. The processor controls rotational speed, displacement, and a direction of the pump rotor.

Abstract: A variable flexibility adhesive system may adhere a surface of a medical infusion device to the skin of a user. The system may be configured to hold a location on the surface stationary with respect to a site on the user's skin. The system may include an adhesive substrate for adhering to the user and an interface where the substrate is held to the surface of the device. The interface may totally and/or partially surround the stationary location. A skirt of the substrate may totally and/or partially surround the interface. Parts of the skirt may be stiffened. Optional features may include tabs for activation of the adhesive and/or a location for peeling the infuser away from the skin. Additionally or alternatively, the interface may have variable flexibility. Additionally or alternatively, the stiffener may include a plastic layer.

Abstract: A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir.

Abstract: Catheters and methods of making catheters are provided which include a connector with a guide wire channel and an inflation channel, a shaft extending from a proximal end to a distal end and having a guide wire lumen and an inflation lumen, the shaft being connected, at its proximal end, to the connector so that said guidewire lumen and inflation lumen are mechanically and fluidly connected with said guide wire channel and inflation channel respectively. The connection is realized in correspondence to a kink portion. Such catheters may include a protective sheath placed around an external wall of the shaft extending from a first sheath end, axially placed at a first distance from the proximal end of the shaft so as to allow direct contact and fixation between the external wall of the shaft and the internal wall of the kink portion, to a second sheath end.

Abstract: An applicator for administering a liquid to a selected location of a patient includes a main body having an interior cavity and a flexible outer wall. A frangible ampoule is configured to contain the liquid and configured to be positioned within the interior cavity of the main body. A hypodermic tube having a proximal end attached to the main body and a distal end. An applicator tip attached to the distal end of the hypodermic tube to dispense the liquid.

Abstract: A medicament injection device arranged to receive a replaceable container subassembly includes front and rear housings releasably connectable to each other. A reloadable drive mechanism is accommodated in the rear housing for acting on the plunger of a replaceable container subassembly for expelling medicament. A needle hider front is slidably arranged within the front housing. A needle shield remover is arranged to connect with a needle shield of the replaceable container subassembly and to be removably inserted into a proximal end of the front housing through the needle hider front. The needle shield remover is adapted to interact with the reloadable drive mechanism such that a user can reload the drive mechanism.

Abstract: An assembly for identifying a power injectable vascular access port, including a vascular access port and an identification feature. The port is structured for power injection and includes a housing and a septum together defining a reservoir. A radiographic feature incorporated into the port is perceivable via x-ray following subcutaneous implantation, the radiographic feature identifying the port as suitable for flowing fluid at a fluid flow rate of at least 1 mL/sec therethrough. A structural feature of the port is perceivable via palpation following subcutaneous implantation, the structural feature identifying the port as suitable for accommodating a pressure within the reservoir of at least 35 psi. The identification feature is separated from the port and confirms that the port is both suitable for flowing fluid at a rate of at least 1 mL/sec therethrough and suitable for accommodating a pressure within the reservoir of at least 35 psi.

Abstract: An irrigation system for a surgical instrument includes an irrigation tube arranged to convey an irrigation fluid and an irrigation clip structurally arranged to receive a portion of the irrigation tube. The irrigation clip includes a proximal portion, a distal portion, a body portion, and an arm portion. The arm portion is structurally configured to selectively attach the irrigation clip to the surgical instrument and to bias the irrigation clip toward the surgical instrument with a biasing force. The irrigation clip includes a tube locking portion structurally arranged to cooperate with the surgical instrument to engage the outer surface portion of the irrigation tube to inhibit rotation and axial displacement of the irrigation tube relative to the irrigation clip in response to the biasing force.

Abstract: Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device.

Abstract: Methods and apparatuses for embolizing an artery in a living subject using a catheter are disclosed. The catheter has a lumen and also has a balloon located near the distal end of the catheter. The distal end of the catheter is introduced into the artery, and the balloon is inflated to form a seal that prevents blood in the artery from flowing past the balloon. A mixture that includes embolic particles and contrast agent is injected through the lumen into the portion of the artery that is distally beyond the balloon. The subject's own blood or another fluid that contains platelets is injected through the lumen into the portion of the artery that is distally beyond the balloon. Subsequently, the balloon is deflated and the distal end of the catheter is withdrawn.

Abstract: A microneedle application device for moving a microneedle array toward a target skin location includes a feedback sensor. The feedback sensor is operably connected to the microneedle application device, and is capable of generating an output corresponding to forces between the target skin location and the microneedle application device.

Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.

Abstract: An assembly including a drug delivery device and a monitoring device adapted to detect an action taking place in the drug delivery device. The drug delivery device including a main portion having a drug expelling mechanism for expelling drug from the reservoir through an outlet, a housing in which at least a portion of the expelling mechanism is arranged, and a member able to attach a cover to the drug delivery device. The cover is adapted to cover the outlet when mounted. The monitoring device includes a housing portion, a member for detecting an action taking place in the drug delivery device, and at least one member adapted to engage a member present on the main portion. By this arrangement the monitoring device can be placed in a pre-determined position relative to the main portion, allowing efficient transmission of information between the monitoring device and the main portion.

Abstract: A power-injectable access port suitable for providing subcutaneous access to a patient and suitable for power injection. The access port includes a septum, a housing, and a reservoir defined by the septum and the housing. The septum may include a material that seals passages formed by puncturing the septum with a hollow slender element or another suitable access mechanism, and a radiopaque material forming a selected pattern when an x-ray is taken through the septum for identifying the power-injectable access port as being suitable for power injection. The housing and the septum may be structured for accommodating a pressure developed within the reservoir of at least 35 psi. The power-injectable access port may be designed to accommodate a flow rate of at least 1 milliliter per second of a fluid.