Patents Examined by Ivan A Greene
  • Patent number: 12357658
    Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: July 15, 2025
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Muhammad Nawaz, Firdos Alam Khan
  • Patent number: 12318462
    Abstract: Multi-coated nanoparticles including multiple coating layers of chitosan and polyglutamic acid, composition for skin care including the same, and method of manufacturing the same are provided. The nanoparticles have a liposome core layer and coating layers. The core layer includes a bioactive particle and a core hydrogel. Not only is it easy to mass-produce, but also has the effect of steadily releasing bioactive particles for a long period of time due to its high sealing rate and high stability.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: June 3, 2025
    Assignee: BINOTEC CO., LTD.
    Inventors: Yu-Mi Kim, Gi-Hyun Jang
  • Patent number: 12274712
    Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: April 15, 2025
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Muhammad Nawaz, Firdos Alam Khan
  • Patent number: 12220427
    Abstract: The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolic acid) (PLGA-PEG-PLGA) copolymer, or the mixture of same, combined with hyaluronic acid molecules or hyaluronic acid salts, and the method for preparing same. The present invention also concerns injectable pharmaceutical or cosmetic compositions comprising such polymer particles, the method for preparing such compositions, and the use thereof for medical purposes, in particular for the prevention and/or treatment of musculoskeletal diseases, diseases and traumatic conditions of the skin, oral disorders, vaginal mucosa dryness and urinary infections or cystitis, dryness of the eye membrane and eye infections, obesity, and the use of same to combat ageing of the skin and/or for repairing the dermal tissue (mesotherapy).
    Type: Grant
    Filed: February 14, 2023
    Date of Patent: February 11, 2025
    Assignee: IBSA PHARMA SAS
    Inventors: Yannis Guillemin, Jean-Noël Gouze
  • Patent number: 12220430
    Abstract: Silver and titanium oxide nanoparticles produced with Fomes fomentarius or Fomitopsis pinicola aqueous extracts and methods for treating bacterial infections or cancer using them.
    Type: Grant
    Filed: April 17, 2023
    Date of Patent: February 11, 2025
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Suriya Rehman, Rabindran Jermy
  • Patent number: 12201691
    Abstract: Provided is a core-shell structure having an excellent immediate effect in transdermal absorption of an active ingredient. A core-shell structure comprising a core portion containing an active ingredient, and a shell portion containing a surfactant having an HLB value of 4 to 14, the core portion being solid, and the surfactant containing a saturated hydrocarbon group having 7 to 15 carbon atoms or an unsaturated hydrocarbon group having 7 to 17 carbon atoms.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: January 21, 2025
    Assignee: SEKISUI CHEMICAL CO., LTD.
    Inventors: Daichi Kawamura, Takayuki Akamine, Saori Tone, Yuuta Nakamura, Izumi Matsumoto, Kazushi Itou
  • Patent number: 12133864
    Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.
    Type: Grant
    Filed: July 9, 2024
    Date of Patent: November 5, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Muhammad Nawaz, Firdos Alam Khan
  • Patent number: 12102717
    Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.
    Type: Grant
    Filed: May 22, 2023
    Date of Patent: October 1, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
  • Patent number: 12102718
    Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.
    Type: Grant
    Filed: March 12, 2024
    Date of Patent: October 1, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
  • Patent number: 12102716
    Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: October 1, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
  • Patent number: 12090169
    Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.
    Type: Grant
    Filed: March 8, 2024
    Date of Patent: September 17, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Muhammad Nawaz, Firdos Alam Khan
  • Patent number: 12083231
    Abstract: The preparation method of a starch-based double-loaded functional nanoparticle includes: performing restrictive hydrolysis treatment on egg high-density lipoprotein using proteases to obtain the polypeptide; performing self-assembling on a mixed system containing the polypeptide and quercetin under the alkaline condition to form a micelle nanoparticle; performing covalent grafting reaction on a mixed system containing the micelle nanoparticle and anthocyanin under the alkaline condition to form a graft; and electrostatically compounding carboxymethyl dextrin with the graft to obtain the starch-based double-loaded functional nanoparticle. In the preparation method, raw materials derived from natural sources are used, and the self-assembled colloid nanoparticle with good properties can be obtained by adjusting the pH without any organic reagents.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: September 10, 2024
    Assignee: HEFEI UNIVERSITY OF TECHNOLOGY
    Inventors: Bao Zhang, Wenjie Liu, Han Tao, Xiaolong Li, Pin Chen, Rumeng Wang
  • Patent number: 12016856
    Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders. The methods generally comprise administering to a mammal in need thereof a pharmaceutically effective amount of a compound, or a pharmaceutical composition comprising such a compound, that is designed to be substantially active in the gastrointestinal (GI) tract to inhibit NHE-mediated antiport of sodium ions and hydrogen ions therein.
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: June 25, 2024
    Assignee: Ardelyx, Inc.
    Inventors: Dominique Charmot, Marc Navre, Christopher Carreras, Noah Bell, Michael Leadbetter, Jeffrey W. Jacobs
  • Patent number: 12017917
    Abstract: Particulate material comprising rough mesoporous hollow nanoparticles. The rough mesoporous hollow nanoparticles may comprise a mesoporous shell, the external surface of which has projections thereon, the projections having smaller sizes than the particle size. The particulate material may be used to deliver active agents, such as insecticides and pesticides. The active agents can enter into the hollow core of the particles and be protected from degradation by sunlight. The rough surface of the particles retains the particles on plant leaves or animal hair. Methods for forming the particles are also described. Carbon particles and methods for forming carbon particles are also described.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: June 25, 2024
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Chengzhong Yu, Meihua Yu, Hongwei Zhang, Yusilawati Ahmad Nor, Hao Song, Neena Mitter
  • Patent number: 11980638
    Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: May 14, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Muhammad Nawaz, Firdos Alam Khan
  • Patent number: 11957789
    Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.
    Type: Grant
    Filed: September 28, 2023
    Date of Patent: April 16, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
  • Patent number: 11744922
    Abstract: The present disclosure relates generally to tissue engineering. Disclosed herein are biomimetic sponges useful for tissue regeneration and methods for making biomimetic sponges.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: September 5, 2023
    Assignee: Saint Louis University
    Inventors: Koyal Garg, Gabriel Haas
  • Patent number: 11738039
    Abstract: The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolicacid) (PLGA-PEG-PLGA) copolymer, or the mixture of same, combined with hyaluronic acid molecules or hyaluronic acid salts, and the method for preparing same. The present invention also concerns injectable pharmaceutical or cosmetic compositions comprising such polymer particles, the method for preparing such compositions, and the use thereof for medical purposes, in particular for the prevention and/or treatment of musculoskeletal diseases, diseases and traumatic conditions of the skin, oral disorders, vaginal mucosa dryness and urinary infections or cystitis, dryness of the eye membrane and eye infections, obesity, and the use of same to combat ageing of the skin and/or for repairing the dermal tissue (mesotherapy).
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 29, 2023
    Assignee: IBSA PHARMA SAS
    Inventors: Yannis Guillemin, Dominique Vacher, Jean-Noël Gouze
  • Patent number: 11738044
    Abstract: The present invention relates to zirconium silicate compositions having a lead content that is below 0.6 ppm and methods of manufacturing zirconium silicate at reactor volumes exceeding 200-L with a lead content below 1.1 ppm. The lead content of the zirconium silicate of this invention are within the levels that are considered acceptable for extended use given the dose requirements for zirconium silicate.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: August 29, 2023
    Assignee: ZS PHARMA, INC.
    Inventors: Donald Jeffrey Keyser, Alvaro F. Guillem
  • Patent number: 11701329
    Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: July 18, 2023
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar