Patents Examined by Ivan A Greene
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Patent number: 12357658Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.Type: GrantFiled: June 29, 2023Date of Patent: July 15, 2025Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Muhammad Nawaz, Firdos Alam Khan
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Patent number: 12318462Abstract: Multi-coated nanoparticles including multiple coating layers of chitosan and polyglutamic acid, composition for skin care including the same, and method of manufacturing the same are provided. The nanoparticles have a liposome core layer and coating layers. The core layer includes a bioactive particle and a core hydrogel. Not only is it easy to mass-produce, but also has the effect of steadily releasing bioactive particles for a long period of time due to its high sealing rate and high stability.Type: GrantFiled: May 12, 2021Date of Patent: June 3, 2025Assignee: BINOTEC CO., LTD.Inventors: Yu-Mi Kim, Gi-Hyun Jang
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Patent number: 12274712Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.Type: GrantFiled: June 29, 2023Date of Patent: April 15, 2025Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Muhammad Nawaz, Firdos Alam Khan
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Patent number: 12220427Abstract: The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolic acid) (PLGA-PEG-PLGA) copolymer, or the mixture of same, combined with hyaluronic acid molecules or hyaluronic acid salts, and the method for preparing same. The present invention also concerns injectable pharmaceutical or cosmetic compositions comprising such polymer particles, the method for preparing such compositions, and the use thereof for medical purposes, in particular for the prevention and/or treatment of musculoskeletal diseases, diseases and traumatic conditions of the skin, oral disorders, vaginal mucosa dryness and urinary infections or cystitis, dryness of the eye membrane and eye infections, obesity, and the use of same to combat ageing of the skin and/or for repairing the dermal tissue (mesotherapy).Type: GrantFiled: February 14, 2023Date of Patent: February 11, 2025Assignee: IBSA PHARMA SASInventors: Yannis Guillemin, Jean-Noël Gouze
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Patent number: 12220430Abstract: Silver and titanium oxide nanoparticles produced with Fomes fomentarius or Fomitopsis pinicola aqueous extracts and methods for treating bacterial infections or cancer using them.Type: GrantFiled: April 17, 2023Date of Patent: February 11, 2025Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Suriya Rehman, Rabindran Jermy
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Patent number: 12201691Abstract: Provided is a core-shell structure having an excellent immediate effect in transdermal absorption of an active ingredient. A core-shell structure comprising a core portion containing an active ingredient, and a shell portion containing a surfactant having an HLB value of 4 to 14, the core portion being solid, and the surfactant containing a saturated hydrocarbon group having 7 to 15 carbon atoms or an unsaturated hydrocarbon group having 7 to 17 carbon atoms.Type: GrantFiled: August 11, 2020Date of Patent: January 21, 2025Assignee: SEKISUI CHEMICAL CO., LTD.Inventors: Daichi Kawamura, Takayuki Akamine, Saori Tone, Yuuta Nakamura, Izumi Matsumoto, Kazushi Itou
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Patent number: 12133864Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.Type: GrantFiled: July 9, 2024Date of Patent: November 5, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Muhammad Nawaz, Firdos Alam Khan
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Patent number: 12102717Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.Type: GrantFiled: May 22, 2023Date of Patent: October 1, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
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Patent number: 12102718Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.Type: GrantFiled: March 12, 2024Date of Patent: October 1, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
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Patent number: 12102716Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.Type: GrantFiled: August 31, 2022Date of Patent: October 1, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
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Patent number: 12090169Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.Type: GrantFiled: March 8, 2024Date of Patent: September 17, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Muhammad Nawaz, Firdos Alam Khan
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Patent number: 12083231Abstract: The preparation method of a starch-based double-loaded functional nanoparticle includes: performing restrictive hydrolysis treatment on egg high-density lipoprotein using proteases to obtain the polypeptide; performing self-assembling on a mixed system containing the polypeptide and quercetin under the alkaline condition to form a micelle nanoparticle; performing covalent grafting reaction on a mixed system containing the micelle nanoparticle and anthocyanin under the alkaline condition to form a graft; and electrostatically compounding carboxymethyl dextrin with the graft to obtain the starch-based double-loaded functional nanoparticle. In the preparation method, raw materials derived from natural sources are used, and the self-assembled colloid nanoparticle with good properties can be obtained by adjusting the pH without any organic reagents.Type: GrantFiled: April 8, 2022Date of Patent: September 10, 2024Assignee: HEFEI UNIVERSITY OF TECHNOLOGYInventors: Bao Zhang, Wenjie Liu, Han Tao, Xiaolong Li, Pin Chen, Rumeng Wang
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Patent number: 12016856Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders. The methods generally comprise administering to a mammal in need thereof a pharmaceutically effective amount of a compound, or a pharmaceutical composition comprising such a compound, that is designed to be substantially active in the gastrointestinal (GI) tract to inhibit NHE-mediated antiport of sodium ions and hydrogen ions therein.Type: GrantFiled: April 1, 2022Date of Patent: June 25, 2024Assignee: Ardelyx, Inc.Inventors: Dominique Charmot, Marc Navre, Christopher Carreras, Noah Bell, Michael Leadbetter, Jeffrey W. Jacobs
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Patent number: 12017917Abstract: Particulate material comprising rough mesoporous hollow nanoparticles. The rough mesoporous hollow nanoparticles may comprise a mesoporous shell, the external surface of which has projections thereon, the projections having smaller sizes than the particle size. The particulate material may be used to deliver active agents, such as insecticides and pesticides. The active agents can enter into the hollow core of the particles and be protected from degradation by sunlight. The rough surface of the particles retains the particles on plant leaves or animal hair. Methods for forming the particles are also described. Carbon particles and methods for forming carbon particles are also described.Type: GrantFiled: April 27, 2022Date of Patent: June 25, 2024Assignee: THE UNIVERSITY OF QUEENSLANDInventors: Chengzhong Yu, Meihua Yu, Hongwei Zhang, Yusilawati Ahmad Nor, Hao Song, Neena Mitter
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Patent number: 11980638Abstract: A method of making Cu—Ag3PO4 nanoparticles is provided. The method includes forming a mixture of at least one silver salt, at least one phosphate salt, and at least one copper (II) salt. The method further includes dissolving the mixture in water. The method further includes sonicating the mixture. The method further includes precipitating the Cu—Ag3PO4 nanoparticles or “nanoparticles”. The copper is present in the nanoparticles in an amount of 2 to 23 weight percent (wt. %) based on the total weight of the Cu—Ag3PO4. The nanoparticles of the present disclosure find application in treating cervical cancer, and colorectal cancer. The nanoparticles may also be used in photodegrading environmental pollutants.Type: GrantFiled: January 19, 2022Date of Patent: May 14, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Muhammad Nawaz, Firdos Alam Khan
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Patent number: 11957789Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.Type: GrantFiled: September 28, 2023Date of Patent: April 16, 2024Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar
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Patent number: 11744922Abstract: The present disclosure relates generally to tissue engineering. Disclosed herein are biomimetic sponges useful for tissue regeneration and methods for making biomimetic sponges.Type: GrantFiled: October 29, 2018Date of Patent: September 5, 2023Assignee: Saint Louis UniversityInventors: Koyal Garg, Gabriel Haas
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Patent number: 11738039Abstract: The present invention concerns polymer particles made from poly(lactic-co-glycolic acid) (PLGA) polymer, poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolicacid) (PLGA-PEG-PLGA) copolymer, or the mixture of same, combined with hyaluronic acid molecules or hyaluronic acid salts, and the method for preparing same. The present invention also concerns injectable pharmaceutical or cosmetic compositions comprising such polymer particles, the method for preparing such compositions, and the use thereof for medical purposes, in particular for the prevention and/or treatment of musculoskeletal diseases, diseases and traumatic conditions of the skin, oral disorders, vaginal mucosa dryness and urinary infections or cystitis, dryness of the eye membrane and eye infections, obesity, and the use of same to combat ageing of the skin and/or for repairing the dermal tissue (mesotherapy).Type: GrantFiled: October 9, 2020Date of Patent: August 29, 2023Assignee: IBSA PHARMA SASInventors: Yannis Guillemin, Dominique Vacher, Jean-Noël Gouze
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Patent number: 11738044Abstract: The present invention relates to zirconium silicate compositions having a lead content that is below 0.6 ppm and methods of manufacturing zirconium silicate at reactor volumes exceeding 200-L with a lead content below 1.1 ppm. The lead content of the zirconium silicate of this invention are within the levels that are considered acceptable for extended use given the dose requirements for zirconium silicate.Type: GrantFiled: May 17, 2019Date of Patent: August 29, 2023Assignee: ZS PHARMA, INC.Inventors: Donald Jeffrey Keyser, Alvaro F. Guillem
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Patent number: 11701329Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”). It also is directed to a method for making uncalcined HSS, calcined HSS from which phenyl groups have been removed, and HSS incorporating particles of Fe3O4, as well as compositions containing HSS.Type: GrantFiled: September 30, 2022Date of Patent: July 18, 2023Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Ayhan Bozkurt, Seyda Tugba Gunday Anil, Firdos Alam Khan, Sultan Akhtar